A0QCA6 (PHS_MYCA1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative pterin-4-alpha-carbinolamine dehydratase
Short name=PHS
EC=4.2.1.96

Alternative name(s):
4-alpha-hydroxy-tetrahydropterin dehydratase
Pterin carbinolamine dehydratase
Short name=PCD

Gene names

Ordered Locus Names:

MAV_1299

Organism

Mycobacterium avium (strain 104) [Complete proteome] [HAMAP]

Taxonomic identifier

243243 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium avium complex (MAC)

Protein attributes

Sequence length	94 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O. HAMAP MF_00434
Sequence similarities	Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

Ontologies

Keywords
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tetrahydrobiopterin biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	4-alpha-hydroxytetrahydrobiopterin dehydratase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 94	94	Putative pterin-4-alpha-carbinolamine dehydratase HAMAP MF_00434		PRO_1000050420

Sequences

	Sequence		Length	Mass (Da)
	A0QCA6 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: C1648FA8A51CAFD8	FASTA	94	10,396
	10 20 30 40 50 60 MAVLTDEQID AALPDLDGWE RADGALRRSI KFPSFLDGID AVRRVAEHAE SKDHHPDIDI 70 80 90 RWRTVTFALV THSEGGITQN DVDMARDING IVGS

References

[1]	Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 104.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000479 Genomic DNA. Translation: ABK67400.1.
RefSeq	YP_880544.1. NC_008595.1.
3D structure databases
ProteinModelPortal	A0QCA6.
ModBase	Search...
Protein-protein interaction databases
STRING	A0QCA6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000013373; EBMYCP00000013259; EBMYCG00000013371.
GeneID	4529853.
GenomeReviews	Gene locus MAV_1299 in contig CP000479_GR.
KEGG	mav:MAV_1299.
PATRIC	17984341. VBIMycAvi38287_1272.
TIGR	MAV_1299.
Phylogenomic databases
eggNOG	COG2154.
GeneTree	EBGT00050000016936.
HOGENOM	HBG705804.
OMA	EHAESKD.
ProtClustDB	PRK00823.
Enzyme and pathway databases
BioCyc	MAVI243243:MAV_1299-MONOMER.
Family and domain databases
HAMAP	MF_00434. Pterin_4_alpha. [Tree]
InterPro	IPR001533. Trans/pterin_deHydtase. [Graphical view]
Gene3D	G3DSA:3.30.1360.20. Trans_pterinDh. 1 hit.
KO	K01724.
PANTHER	PTHR12599. Trans_pterinDh. 1 hit.
Pfam	PF01329. Pterin_4a. 1 hit. [Graphical view]
SUPFAM	SSF55248. Trans_pterinDh. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PHS_MYCA1

Accession

Primary (citable) accession number: A0QCA6

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	January 9, 2007
Last modified:	December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program