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A0QBN4

- G6PI_MYCA1

UniProt

A0QBN4 - G6PI_MYCA1

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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Mycobacterium avium (strain 104)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei358 – 3581Proton donorUniRule annotation
Active sitei389 – 3891UniRule annotation
Active sitei515 – 5151UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciMAVI243243:GH3Y-1068-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:MAV_1068
OrganismiMycobacterium avium (strain 104)
Taxonomic identifieri243243 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium avium complex (MAC)
ProteomesiUP000001574: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 554554Glucose-6-phosphate isomerasePRO_1000013987Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243243.MAV_1068.

Structurei

3D structure databases

ProteinModelPortaliA0QBN4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261371.
KOiK01810.
OMAiLITEEVM.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0QBN4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTSVHTLPDI TATPAWDALR KHHDRIGDTH LRQFFEEDPD RGRELTVTVG
60 70 80 90 100
DLYIDYSKHR VTRETLRLLV DLARTAKLEE RRDQMFAGVH INTSEDRAVL
110 120 130 140 150
HTALRLPRDA ELIVDGRNVV ADVHEVLDAM GEFTDRLRSG EWTGATGKRI
160 170 180 190 200
STVVNIGIGG SDLGPVMVYQ ALRHYADAGI SARFVSNVDP ADLIATLADL
210 220 230 240 250
DPATTLFIVA SKTFSTLETL TNATAARRWI TDALGDAAVA HHFVAVSTNK
260 270 280 290 300
RLVDDFGINT DNMFGFWDWV GGRYSVDSAI GLSVMAVIGR EAFADFLSGF
310 320 330 340 350
HIVDRHFQTA PLESNAPVLL GLIGLWYSNF MGAQSRAVLP YSNDLARFAA
360 370 380 390 400
YLQQLTMESN GKSTRADGSP VTTDTGEIFW GEPGTNGQHA FYQLLHQGTR
410 420 430 440 450
LVPADFIGFS QPIDDLPTAE GSGSMHDLLM SNFFAQTQVL AFGKTAEEIA
460 470 480 490 500
AEGTPADIVP HKVMPGNRPS TSILANRLTP SVLGQLIALY EHQVFTEGVI
510 520 530 540 550
WGIDSFDQWG VELGKTQAKA LLPVITADNS PAPQSDSSTD ALVRRYRSER

GRTS
Length:554
Mass (Da):60,652
Last modified:January 9, 2007 - v1
Checksum:i780F82619506EF92
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000479 Genomic DNA. Translation: ABK66481.1.
RefSeqiWP_011723919.1. NC_008595.1.
YP_880322.1. NC_008595.1.

Genome annotation databases

EnsemblBacteriaiABK66481; ABK66481; MAV_1068.
GeneIDi4529585.
KEGGimav:MAV_1068.
PATRICi17983871. VBIMycAvi38287_1041.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000479 Genomic DNA. Translation: ABK66481.1 .
RefSeqi WP_011723919.1. NC_008595.1.
YP_880322.1. NC_008595.1.

3D structure databases

ProteinModelPortali A0QBN4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243243.MAV_1068.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABK66481 ; ABK66481 ; MAV_1068 .
GeneIDi 4529585.
KEGGi mav:MAV_1068.
PATRICi 17983871. VBIMycAvi38287_1041.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261371.
KOi K01810.
OMAi LITEEVM.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
UPA00138 .
BioCyci MAVI243243:GH3Y-1068-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M.
    Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 104.

Entry informationi

Entry nameiG6PI_MYCA1
AccessioniPrimary (citable) accession number: A0QBN4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 9, 2007
Last modified: October 29, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3