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A0QBN4

- G6PI_MYCA1

UniProt

A0QBN4 - G6PI_MYCA1

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Protein
Glucose-6-phosphate isomerase
Gene
pgi, MAV_1068
Organism
Mycobacterium avium (strain 104)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei358 – 3581Proton donor By similarity
Active sitei389 – 3891 By similarity
Active sitei515 – 5151 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciMAVI243243:GH3Y-1068-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:MAV_1068
OrganismiMycobacterium avium (strain 104)
Taxonomic identifieri243243 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium avium complex (MAC)
ProteomesiUP000001574: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 554554Glucose-6-phosphate isomeraseUniRule annotation
PRO_1000013987Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243243.MAV_1068.

Structurei

3D structure databases

ProteinModelPortaliA0QBN4.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261371.
KOiK01810.
OMAiLITEEVM.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0QBN4-1 [UniParc]FASTAAdd to Basket

« Hide

MTSVHTLPDI TATPAWDALR KHHDRIGDTH LRQFFEEDPD RGRELTVTVG    50
DLYIDYSKHR VTRETLRLLV DLARTAKLEE RRDQMFAGVH INTSEDRAVL 100
HTALRLPRDA ELIVDGRNVV ADVHEVLDAM GEFTDRLRSG EWTGATGKRI 150
STVVNIGIGG SDLGPVMVYQ ALRHYADAGI SARFVSNVDP ADLIATLADL 200
DPATTLFIVA SKTFSTLETL TNATAARRWI TDALGDAAVA HHFVAVSTNK 250
RLVDDFGINT DNMFGFWDWV GGRYSVDSAI GLSVMAVIGR EAFADFLSGF 300
HIVDRHFQTA PLESNAPVLL GLIGLWYSNF MGAQSRAVLP YSNDLARFAA 350
YLQQLTMESN GKSTRADGSP VTTDTGEIFW GEPGTNGQHA FYQLLHQGTR 400
LVPADFIGFS QPIDDLPTAE GSGSMHDLLM SNFFAQTQVL AFGKTAEEIA 450
AEGTPADIVP HKVMPGNRPS TSILANRLTP SVLGQLIALY EHQVFTEGVI 500
WGIDSFDQWG VELGKTQAKA LLPVITADNS PAPQSDSSTD ALVRRYRSER 550
GRTS 554
Length:554
Mass (Da):60,652
Last modified:January 9, 2007 - v1
Checksum:i780F82619506EF92
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000479 Genomic DNA. Translation: ABK66481.1.
RefSeqiWP_011723919.1. NC_008595.1.
YP_880322.1. NC_008595.1.

Genome annotation databases

EnsemblBacteriaiABK66481; ABK66481; MAV_1068.
GeneIDi4529585.
KEGGimav:MAV_1068.
PATRICi17983871. VBIMycAvi38287_1041.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000479 Genomic DNA. Translation: ABK66481.1 .
RefSeqi WP_011723919.1. NC_008595.1.
YP_880322.1. NC_008595.1.

3D structure databases

ProteinModelPortali A0QBN4.
ModBasei Search...

Protein-protein interaction databases

STRINGi 243243.MAV_1068.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABK66481 ; ABK66481 ; MAV_1068 .
GeneIDi 4529585.
KEGGi mav:MAV_1068.
PATRICi 17983871. VBIMycAvi38287_1041.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261371.
KOi K01810.
OMAi LITEEVM.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
UPA00138 .
BioCyci MAVI243243:GH3Y-1068-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M.
    Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 104.

Entry informationi

Entry nameiG6PI_MYCA1
AccessioniPrimary (citable) accession number: A0QBN4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 9, 2007
Last modified: September 3, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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