A0QAT5 (A0QAT5_MYCA1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase RuleBase RU004370
EC=6.3.3.1 RuleBase RU004370

Gene names

Name:	purM EMBL ABK66422.1
Ordered Locus Names:	MAV_0748

Organism

Mycobacterium avium (strain 104) [Complete proteome] [HAMAP]

Taxonomic identifier

243243 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium avium complex (MAC)

Protein attributes

Sequence length	364 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole. RuleBase RU004370 SAAS SAAS004733
Pathway	Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2. RuleBase RU004371 SAAS SAAS004733
Subcellular location	Cytoplasm By similarity SAAS SAAS004733.
Sequence similarities	Belongs to the AIR synthase family. RuleBase RU004370

Ontologies

Keywords
Biological process	Purine biosynthesis SAAS SAAS004733
Cellular component	Cytoplasm SAAS SAAS004733
Ligand	ATP-binding SAAS SAAS004733 Nucleotide-binding
Molecular function	Ligase RuleBase RU004370 SAAS SAAS004733 EMBL ABK66422.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	'de novo' IMP biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoribosylformylglycinamidine cyclo-ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0QAT5 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 25D77A00B7E9353F	FASTA	364	38,258
	10 20 30 40 50 60 MTDPGKSPGR HSGSQGITYA SAGVDIEAGD RAVELFKPLA TKATRPEVRG GLGGFAGLFA 70 80 90 100 110 120 LRGEYREPLL AASTDGVGTK LAVAQAMDKH DTVGLDLVAM VVDDLVVCGA EPLFLQDYIA 130 140 150 160 170 180 VGRTVPERLS AIVSGIAEGC VRAGCALLGG ETAEHPGLME PDHYDISATG VGVVEADDVL 190 200 210 220 230 240 GPDRVKPGDV IIAMGSSGLH SNGYSLARTV LLEIDRMNLE GYVEEFGRTL GEELLEPTRI 250 260 270 280 290 300 YAKDCLALAA ETHVRTFCHV TGGGLAGNLA RVIPHGLVAE LDRGTWTPAP VFAMIAQRGR 310 320 330 340 350 360 VTREEMEKTF NMGVGMIAVV APEDTDRALA ILTARHLDCW VLGTVGKGGK AGPRAKLVGQ HPRF

References

[1]	Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000479 Genomic DNA. Translation: ABK66422.1.
RefSeq	YP_880023.1. NC_008595.1.
3D structure databases
ProteinModelPortal	A0QAT5.
ModBase	Search...
Protein-protein interaction databases
STRING	A0QAT5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000009964; EBMYCP00000009850; EBMYCG00000009962.
GeneID	4528611.
GenomeReviews	Gene locus MAV_0748 in contig CP000479_GR.
KEGG	mav:MAV_0748.
PATRIC	17983231. VBIMycAvi38287_0727.
TIGR	MAV_0748.
Phylogenomic databases
eggNOG	COG0150.
GeneTree	EBGT00050000016383.
HOGENOM	HBG531222.
OMA	PENIPRV.
ProtClustDB	PRK05385.
Family and domain databases
InterPro	IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR004733. PurM_cligase. IPR016188. PurM_N-like. [Graphical view]
KO	K01933.
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
SUPFAM	SSF56042. AIR_synth_C. 1 hit. SSF55326. PurM_N-like. 1 hit.
TIGRFAMs	TIGR00878. PurM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A0QAT5_MYCA1

Accession

Primary (citable) accession number: A0QAT5

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	December 14, 2011
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)