A0Q9F3 (PATR_MYCA1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative phenylalanine aminotransferase
EC=2.6.1.-

Gene names

Name:	pat
Ordered Locus Names:	MAV_0250

Organism

Mycobacterium avium (strain 104) [Complete proteome] [HAMAP]

Taxonomic identifier

243243 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium avium complex (MAC)

Protein attributes

Sequence length	355 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May catalyze the transamination reaction in phenylalanine biosynthesis By similarity. HAMAP MF_01513
Cofactor	Pyridoxal phosphate By similarity. HAMAP MF_01513
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

Ontologies

Keywords
Ligand	Pyridoxal phosphate
Molecular function	Aminotransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	histidine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	1-aminocyclopropane-1-carboxylate synthase activity Inferred from electronic annotation. Source: InterPro histidinol-phosphate transaminase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 355	355	Putative phenylalanine aminotransferase HAMAP MF_01513		PRO_1000024494
Amino acid modifications
	Modified residue	217	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A0Q9F3 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 7444BA6C61940A2C	FASTA	355	38,019
	10 20 30 40 50 60 MTARLRPELA GLPVYVPGKN VPGSIKLASN ETVYGPLPSV HAAIERAVAI VNRYPDNACV 70 80 90 100 110 120 DLKAALAMHL GSDVAPEQIA VGSGSVTLCQ QLVQITSAAG DEVMMGWRSF ECYLPIVQVA 130 140 150 160 170 180 GAIAVKVPLR EHTYDLDAML AAITDRTRLI FVCNPNNPTS TVVDPDALVR FVDAVPADIL 190 200 210 220 230 240 IAIDEAYVEY IRDGLLPNSL ELALSRSNVV VLRTFSKAYG LAGLRVGYAI GHPELITALD 250 260 270 280 290 300 KVVMPFAVTN VAQAAAIASL EASGELMART DALVAERTRV STTLRDAGFE LPPSQANFLW 310 320 330 340 350 LPLGSRTEDF VQEAANARLV VRPFASEGVR VTIGAPAEND ALLQFACDWI ARTER

References

[1]	Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 104.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000479 Genomic DNA. Translation: ABK66277.1.
RefSeq	YP_879541.1. NC_008595.1.
3D structure databases
ProteinModelPortal	A0Q9F3.
ModBase	Search...
Protein-protein interaction databases
STRING	A0Q9F3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000013746; EBMYCP00000013632; EBMYCG00000013744.
GeneID	4525854.
GenomeReviews	Gene locus MAV_0250 in contig CP000479_GR.
KEGG	mav:MAV_0250.
PATRIC	17982248. VBIMycAvi38287_0244.
TIGR	MAV_0250.
Phylogenomic databases
eggNOG	COG0079.
GeneTree	EBGT00070000031717.
HOGENOM	HBG646350.
OMA	NNTKIVW.
ProtClustDB	PRK03321.
Enzyme and pathway databases
BioCyc	MAVI243243:MAV_0250-MONOMER.
Family and domain databases
HAMAP	MF_01513. Phe_aminotrans_2. [Tree]
InterPro	IPR001176. ACC_synthase. IPR001917. Aminotrans_II_pyridoxalP_BS. IPR004839. Aminotransferase_I/II. IPR024892. AroT. IPR005861. HisP_aminotrans. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00817.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
PRINTS	PR00753. ACCSYNTHASE.
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01141. HisC. 1 hit.
PROSITE	PS00599. AA_TRANSFER_CLASS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PATR_MYCA1

Accession

Primary (citable) accession number: A0Q9F3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	January 9, 2007
Last modified:	January 25, 2012
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program