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Protein

Glutamate decarboxylase

Gene

FTN_1701

Organism
Francisella tularensis subsp. novicida (strain U112)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciFNOV401614:GC4M-1700-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:FTN_1701Imported
OrganismiFrancisella tularensis subsp. novicida (strain U112)Imported
Taxonomic identifieri401614 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella
ProteomesiUP000000762 Componenti: Chromosome

Structurei

3D structure databases

ProteinModelPortaliA0Q8J3.
SMRiA0Q8J3. Positions 9-435.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiERQTGID.
OrthoDBiEOG6TFCPW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

A0Q8J3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALHGKKDTI NNLDFFEQSL PKFKLPLNSQ DPLEVYQEIK DELMLDGNSK
60 70 80 90 100
QNLATFCQTE VDDFIHKLMD DCIDKNMIDK DEYPQTAEIE SRCVNILANL
110 120 130 140 150
WNSSAENAIG CSTTGSSEAA MLGGMAMKWR WRDKMKAQGK DYTKPNLVTG
160 170 180 190 200
PVQVCWHKFA RYWDIELREI PMSNESLIMT PEAVLERCDE NTIGVVPTLG
210 220 230 240 250
VTFTGQYEPV EQVCKALDDF ERQTGIDIPV HVDAASGGFL APFVEPELKW
260 270 280 290 300
DFRLPRVKSI NSSGHKFGLS PLGVGWVIWA DKKYLPDDLI FNVNYLGGNM
310 320 330 340 350
PTFALNFSRP GGQIVAQYYN FVRLGFEGYK KVHQLCYDVA EYIAKELRKM
360 370 380 390 400
EIFEIIHAGE GGIPAVSWSL KATKEYSLFD ISEKVRAKGW QIAAYTMPTN
410 420 430 440
REDLVVMRVL VRRGFSYDLA QLMIRDLVAV INSLEGKLKI LKRSSFAH
Length:448
Mass (Da):50,828
Last modified:January 9, 2007 - v1
Checksum:iB5798B19FE0FA0D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000439 Genomic DNA. Translation: ABK90558.1.
RefSeqiWP_003041366.1. NC_008601.1.
YP_899312.1. NC_008601.1.

Genome annotation databases

EnsemblBacteriaiABK90558; ABK90558; FTN_1701.
KEGGiftn:FTN_1701.
PATRICi17936601. VBIFraNov128299_1742.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000439 Genomic DNA. Translation: ABK90558.1.
RefSeqiWP_003041366.1. NC_008601.1.
YP_899312.1. NC_008601.1.

3D structure databases

ProteinModelPortaliA0Q8J3.
SMRiA0Q8J3. Positions 9-435.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABK90558; ABK90558; FTN_1701.
KEGGiftn:FTN_1701.
PATRICi17936601. VBIFraNov128299_1742.

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiERQTGID.
OrthoDBiEOG6TFCPW.

Enzyme and pathway databases

BioCyciFNOV401614:GC4M-1700-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: U112Imported.

Entry informationi

Entry nameiA0Q8J3_FRATN
AccessioniPrimary (citable) accession number: A0Q8J3
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: June 24, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.