SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A0Q5R2

- A0Q5R2_FRATN

UniProt

A0Q5R2 - A0Q5R2_FRATN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Galactokinase
Gene
galK, FTN_0685
Organism
Francisella tularensis subsp. novicida (strain U112)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) By similarity.UniRule annotationSAAS annotations

Catalytic activityi

ATP + alpha-D-galactose = ADP + alpha-D-galactose 1-phosphate.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei29 – 291Transition state stabilizer By similarityUniRule annotation
Binding sitei69 – 691ATP By similarityUniRule annotation
Metal bindingi130 – 1301Magnesium By similarityUniRule annotation
Metal bindingi162 – 1621Magnesium By similarityUniRule annotation
Active sitei174 – 1741Proton acceptor By similarityUniRule annotation
Binding sitei224 – 2241Substrate By similarityUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi124 – 1307ATP By similarityUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. galactokinase activity Source: UniProtKB-HAMAP
  3. magnesium ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. galactose metabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationsImported, Transferase

Keywords - Biological processi

Carbohydrate metabolism, Galactose metabolismUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, MagnesiumUniRule annotationSAAS annotations, Metal-bindingUniRule annotationSAAS annotations, Nucleotide-binding

Enzyme and pathway databases

BioCyciFNOV401614:GC4M-684-MONOMER.
UniPathwayiUPA00214.

Names & Taxonomyi

Protein namesi
Recommended name:
GalactokinaseUniRule annotation (EC:2.7.1.6UniRule annotation)
Alternative name(s):
Galactose kinase
Gene namesi
Name:galKUniRule annotationImported
Ordered Locus Names:FTN_0685Imported
OrganismiFrancisella tularensis subsp. novicida (strain U112)Imported
Taxonomic identifieri401614 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella
ProteomesiUP000000762: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Interactioni

Protein-protein interaction databases

STRINGi401614.FTN_0685.

Structurei

3D structure databases

ProteinModelPortaliA0Q5R2.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni35 – 384Substrate binding By similarityUniRule annotation

Sequence similaritiesi

Belongs to the GHMP kinase family. GalK subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0153.
HOGENOMiHOG000241101.
KOiK00849.
OMAiVMPCAIN.
OrthoDBiEOG6DG2SH.

Family and domain databases

Gene3Di3.30.230.10. 1 hit.
3.30.70.890. 1 hit.
HAMAPiMF_00246. Galactokinase.
InterProiIPR000705. Galactokinase.
IPR022963. Galactokinase_bac.
IPR019741. Galactokinase_CS.
IPR019539. GalKase_gal-bd.
IPR013750. GHMP_kinase_C_dom.
IPR006204. GHMP_kinase_N_dom.
IPR006203. GHMP_knse_ATP-bd_CS.
IPR006206. Mevalonate/galactokinase.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
[Graphical view]
PfamiPF10509. GalKase_gal_bdg. 1 hit.
PF08544. GHMP_kinases_C. 1 hit.
PF00288. GHMP_kinases_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000530. Galactokinase. 1 hit.
PRINTSiPR00473. GALCTOKINASE.
PR00959. MEVGALKINASE.
SUPFAMiSSF54211. SSF54211. 1 hit.
SSF55060. SSF55060. 1 hit.
TIGRFAMsiTIGR00131. gal_kin. 1 hit.
PROSITEiPS00106. GALACTOKINASE. 1 hit.
PS00627. GHMP_KINASES_ATP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0Q5R2-1 [UniParc]FASTAAdd to Basket

« Hide

MMDCIKHNLI NRFVELYGRK PQLFFSPGRV NLIGEHTDYN NGFVMPFAIN    50
KGTFIAIAKR DDNIVNVYSE NLDDSSSFDI TKIKQEISNT WQNYIKGVIN 100
IINQNFSSDI KGADIYIFSD LPFGAGLSSS ASLNTALAYA YNDIYQLNIS 150
KIDLAKIAQK VEHEYIGTKC GLMDQMACLF SQQNAATMID CNDNHYDNIP 200
FELDNLSVLI CDTNIKHNLA DSAYNKRRQV CENIARFHSI KSLRELDSQK 250
LEDTKLNFSE EDYKLALHVF TENQRVIEAT KAMVAKDWQK LGKLMYQSHN 300
SLKNDYKVSC DELDYLVELS QNFAGIYGAR MTGGGFGGST IHLLPTKLLK 350
EYTSYLEKNY FQKFNIKPSF YISKACQGTC KL 382
Length:382
Mass (Da):43,488
Last modified:January 9, 2007 - v1
Checksum:iC28B34A038EFE785
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000439 Genomic DNA. Translation: ABK89577.1.
RefSeqiYP_898331.1. NC_008601.1.

Genome annotation databases

EnsemblBacteriaiABK89577; ABK89577; FTN_0685.
GeneIDi4547301.
KEGGiftn:FTN_0685.
PATRICi17934472. VBIFraNov128299_0705.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000439 Genomic DNA. Translation: ABK89577.1 .
RefSeqi YP_898331.1. NC_008601.1.

3D structure databases

ProteinModelPortali A0Q5R2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 401614.FTN_0685.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABK89577 ; ABK89577 ; FTN_0685 .
GeneIDi 4547301.
KEGGi ftn:FTN_0685.
PATRICi 17934472. VBIFraNov128299_0705.

Phylogenomic databases

eggNOGi COG0153.
HOGENOMi HOG000241101.
KOi K00849.
OMAi VMPCAIN.
OrthoDBi EOG6DG2SH.

Enzyme and pathway databases

UniPathwayi UPA00214 .
BioCyci FNOV401614:GC4M-684-MONOMER.

Family and domain databases

Gene3Di 3.30.230.10. 1 hit.
3.30.70.890. 1 hit.
HAMAPi MF_00246. Galactokinase.
InterProi IPR000705. Galactokinase.
IPR022963. Galactokinase_bac.
IPR019741. Galactokinase_CS.
IPR019539. GalKase_gal-bd.
IPR013750. GHMP_kinase_C_dom.
IPR006204. GHMP_kinase_N_dom.
IPR006203. GHMP_knse_ATP-bd_CS.
IPR006206. Mevalonate/galactokinase.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
[Graphical view ]
Pfami PF10509. GalKase_gal_bdg. 1 hit.
PF08544. GHMP_kinases_C. 1 hit.
PF00288. GHMP_kinases_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000530. Galactokinase. 1 hit.
PRINTSi PR00473. GALCTOKINASE.
PR00959. MEVGALKINASE.
SUPFAMi SSF54211. SSF54211. 1 hit.
SSF55060. SSF55060. 1 hit.
TIGRFAMsi TIGR00131. gal_kin. 1 hit.
PROSITEi PS00106. GALACTOKINASE. 1 hit.
PS00627. GHMP_KINASES_ATP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: U112.

Entry informationi

Entry nameiA0Q5R2_FRATN
AccessioniPrimary (citable) accession number: A0Q5R2
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: June 11, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi