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A0Q5P0

- G6PI_FRATN

UniProt

A0Q5P0 - G6PI_FRATN

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Protein

Glucose-6-phosphate isomerase

Gene
pgi, FTN_0663
Organism
Francisella tularensis subsp. novicida (strain U112)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei346 – 3461Proton donor By similarity
Active sitei377 – 3771 By similarity
Active sitei505 – 5051 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciFNOV401614:GC4M-662-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:FTN_0663
OrganismiFrancisella tularensis subsp. novicida (strain U112)
Taxonomic identifieri401614 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella
ProteomesiUP000000762: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 540540Glucose-6-phosphate isomeraseUniRule annotationPRO_1000013967Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi401614.FTN_0663.

Structurei

3D structure databases

ProteinModelPortaliA0Q5P0.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiNCHFVAN.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0Q5P0-1 [UniParc]FASTAAdd to Basket

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MLFCDDSKKY LKEQNINLKN EFDKDDKRVE KFSLKHQNIY FDYSKNLIND    50
YILKSLLESA EKSSLKDKIK QMFNGAKINS TEHRAVLHTA LRDLSSTPLV 100
VDGQDIRQEV TKEKQRVKEL VEKVVSGRWR GFSGKKITDI VNIGIGGSDL 150
GPKMVVRALQ PYHCTDLKVH FVSNVDADSL LQALHVVDPE TTLFIIASKS 200
FSTEETLLNS ISAREWLLDH YEDEKAVANH FVAISSKLDK VKEFGIDLEH 250
CYKMWDWVGG RYSLWSSIGM SIAFAIGYDN FEKLLAGAYS VDKHFKETEF 300
SKNIPVIMAL LASYYSCTYN SQSQALLPYD ERLCYFVDYL QQADMESNGK 350
SVNIAGETVN YQTGVVLWGG VGTNGQHAFH QLLHQGNIFI PVDFIAIATS 400
HHNYDNHQQA LLANCFAQSQ ALMFGQSYDM VYNELLKSGL NETQAKELAA 450
HKVIPGNRPS TTILLDELSP YSLGALIALY EHKIFVQGVL WDINSYDQWG 500
VELGKKLGKN ILKAMNDDSS DEYQNLDDST RQLIAKVKSK 540
Length:540
Mass (Da):61,111
Last modified:January 9, 2007 - v1
Checksum:i898B462FA6513653
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000439 Genomic DNA. Translation: ABK89555.1.
RefSeqiYP_898309.1. NC_008601.1.

Genome annotation databases

EnsemblBacteriaiABK89555; ABK89555; FTN_0663.
GeneIDi4547886.
KEGGiftn:FTN_0663.
PATRICi17934426. VBIFraNov128299_0682.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000439 Genomic DNA. Translation: ABK89555.1 .
RefSeqi YP_898309.1. NC_008601.1.

3D structure databases

ProteinModelPortali A0Q5P0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 401614.FTN_0663.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABK89555 ; ABK89555 ; FTN_0663 .
GeneIDi 4547886.
KEGGi ftn:FTN_0663.
PATRICi 17934426. VBIFraNov128299_0682.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261370.
KOi K01810.
OMAi NCHFVAN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
UPA00138 .
BioCyci FNOV401614:GC4M-662-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: U112.

Entry informationi

Entry nameiG6PI_FRATN
AccessioniPrimary (citable) accession number: A0Q5P0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 9, 2007
Last modified: June 11, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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