ID   A0Q2V4_CLONN            Unreviewed;       572 AA.
AC   A0Q2V4;
DT   09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2007, sequence version 1.
DT   27-MAR-2024, entry version 85.
DE   SubName: Full=Methyl-accepting chemotaxis protein, putative {ECO:0000313|EMBL:ABK62480.1};
GN   OrderedLocusNames=NT01CX_0485 {ECO:0000313|EMBL:ABK62480.1};
OS   Clostridium novyi (strain NT).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=386415 {ECO:0000313|EMBL:ABK62480.1, ECO:0000313|Proteomes:UP000008220};
RN   [1] {ECO:0000313|EMBL:ABK62480.1, ECO:0000313|Proteomes:UP000008220}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NT {ECO:0000313|EMBL:ABK62480.1,
RC   ECO:0000313|Proteomes:UP000008220};
RX   PubMed=17115055; DOI=10.1038/nbt1256;
RA   Bettegowda C., Huang X., Lin J., Cheong I., Kohli M., Szabo S.A., Zhang X.,
RA   Diaz L.A. Jr., Velculescu V.E., Parmigiani G., Kinzler K.W., Vogelstein B.,
RA   Zhou S.;
RT   "The genome and transcriptomes of the anti-tumor agent Clostridium novyi-
RT   NT.";
RL   Nat. Biotechnol. 24:1573-1580(2006).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; CP000382; ABK62480.1; -; Genomic_DNA.
DR   RefSeq; WP_011722938.1; NC_008593.1.
DR   AlphaFoldDB; A0Q2V4; -.
DR   STRING; 386415.NT01CX_0485; -.
DR   KEGG; cno:NT01CX_0485; -.
DR   PATRIC; fig|386415.7.peg.1993; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_19_9; -.
DR   Proteomes; UP000008220; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR035440; 4HB_MCP_dom_sf.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR024478; HlyB_4HB_MCP.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF12729; 4HB_MCP_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF47170; Aspartate receptor, ligand-binding domain; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008220};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        191..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          211..266
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          285..456
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   COILED          85..138
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          314..355
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   572 AA;  63472 MW;  81F4D346E6EFA1C6 CRC64;
     MLDNIKVKGK ILLMTGIMAL IAIIVGIIGL FYLGKANNTM EDMYSENIVS INLLLNARNN
     VNRITMDMLN LCLENGQTEY EAKVMKDAEE NLQELSTKLK KYTLTTVDSN EKIMFDNIKS
     IENKYEKVVR EVLELANNDK NEEAYKILKD NSKVIEDFKD EIIKLGDYNI EDAEKTKIIN
     NNQYKSAFKS IILILIMAII LGIGVSILIA RTIVNPLNEI GLYIKRIGQG DFSEKVNEKH
     IKRKDEIGDL IRGTNGMRET SIELIGNILN ESDASISVTE SVFNIVSEVN ASSQEILATT
     EELSAGMEET AASAEEMNAS AREIESSVQN VSNRAEDLSE KCMEVNERAK NLTKSAKDSM
     EDGLNLYEKN KKELVKSIEN SKSVTKINVL LDSIIEITEQ TNLLALNAAI EAARAGEHGK
     GFAVVAEEVR KLAEESSDTA GKIQLIIKDT IKSVEELSGN SQVILDFIND KVLNDYKNFV
     EVGKVYSDDV DYFNSVVTEL KSVCEDALNS TKNVMEVIDN VTLATNEGAE GTSNIANKVG
     ISQKYINQLM EMVVKAKNSS EELGKSVSNF KI
//