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A0Q2R0 (G6PI_CLONN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:NT01CX_0441
OrganismClostridium novyi (strain NT) [Complete proteome] [HAMAP]
Taxonomic identifier386415 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium

Protein attributes

Sequence length450 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 450450Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_1000013957

Sites

Active site2911Proton donor By similarity
Active site3121 By similarity
Active site4261 By similarity

Sequences

Sequence LengthMass (Da)Tools
A0Q2R0 [UniParc].

Last modified January 9, 2007. Version 1.
Checksum: CDCDFE255FDB5F6D

FASTA45050,075
        10         20         30         40         50         60 
MYKSLSLDLT KTKPFLNDYE VEQLQPMVSA AHKLLHEKTG AGNDFLGWID LPVNYDKDEF 

        70         80         90        100        110        120 
ARIKKSAEKI RNNSEALIVI GIGGSYLGAR AAIEMLTHTF GNVASKEARK APQIFYAGNN 

       130        140        150        160        170        180 
ISSTYMADLI ETVKDMDFSV NVISKSGTTT EPAIAFRIFK DLLEKKYGKE GAKERIFATT 

       190        200        210        220        230        240 
DKAKGALRTL ADSEGYETFV IPDDVGGRYS VLTAVGLLPI ATAGVDIDEM MKGAADAREE 

       250        260        270        280        290        300 
YSTDDLSKNT AYRYAAARNA LYNKGKNIEM MVNFEPCLHY IGEWWKQLFG ESEGKDHKGI 

       310        320        330        340        350        360 
FPAAADFSTD LHSMGQYIQE GLRTLVETHL NVEKPRKSVI IEANEDNLDG LNFLAGKDMD 

       370        380        390        400        410        420 
YVNNQAFRGT VIAHNEGEVP NMIINIPELT PYYFGYLVYF FEKSCALSGY LLGVNPFNQP 

       430        440        450 
GVEAYKKNMF ALLGKPGYED MKAEIEAKLQ 

« Hide

References

[1]"The genome and transcriptomes of the anti-tumor agent Clostridium novyi-NT."
Bettegowda C., Huang X., Lin J., Cheong I., Kohli M., Szabo S.A., Zhang X., Diaz L.A. Jr., Velculescu V.E., Parmigiani G., Kinzler K.W., Vogelstein B., Zhou S.
Nat. Biotechnol. 24:1573-1580(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NT.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000382 Genomic DNA. Translation: ABK62455.1.
RefSeqYP_878912.1. NC_008593.1.

3D structure databases

ProteinModelPortalA0Q2R0.
SMRA0Q2R0. Positions 4-449.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING386415.NT01CX_0441.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABK62455; ABK62455; NT01CX_0441.
GeneID4541598.
KEGGcno:NT01CX_0441.
PATRIC19481428. VBICloNov112828_1946.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000100403.
KOK01810.
OMAKVNMFAL.
OrthoDBEOG64R61J.
ProtClustDBPRK14097.

Enzyme and pathway databases

BioCycCNOV386415:GH98-2005-MONOMER.
UniPathwayUPA00109; UER00181.
UPA00138.

Family and domain databases

HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_CLONN
AccessionPrimary (citable) accession number: A0Q2R0
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 9, 2007
Last modified: February 19, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways