ID   A0Q2G2_CLONN            Unreviewed;       570 AA.
AC   A0Q2G2;
DT   09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2007, sequence version 1.
DT   27-MAR-2024, entry version 81.
DE   SubName: Full=Membrane assosiated methyl-accepting chemotaxis protein with HAMP domain {ECO:0000313|EMBL:ABK62392.1};
GN   OrderedLocusNames=NT01CX_0316 {ECO:0000313|EMBL:ABK62392.1};
OS   Clostridium novyi (strain NT).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=386415 {ECO:0000313|EMBL:ABK62392.1, ECO:0000313|Proteomes:UP000008220};
RN   [1] {ECO:0000313|EMBL:ABK62392.1, ECO:0000313|Proteomes:UP000008220}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NT {ECO:0000313|EMBL:ABK62392.1,
RC   ECO:0000313|Proteomes:UP000008220};
RX   PubMed=17115055; DOI=10.1038/nbt1256;
RA   Bettegowda C., Huang X., Lin J., Cheong I., Kohli M., Szabo S.A., Zhang X.,
RA   Diaz L.A. Jr., Velculescu V.E., Parmigiani G., Kinzler K.W., Vogelstein B.,
RA   Zhou S.;
RT   "The genome and transcriptomes of the anti-tumor agent Clostridium novyi-
RT   NT.";
RL   Nat. Biotechnol. 24:1573-1580(2006).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; CP000382; ABK62392.1; -; Genomic_DNA.
DR   RefSeq; WP_011722799.1; NC_008593.1.
DR   AlphaFoldDB; A0Q2G2; -.
DR   STRING; 386415.NT01CX_0316; -.
DR   KEGG; cno:NT01CX_0316; -.
DR   PATRIC; fig|386415.7.peg.1848; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_27_9; -.
DR   Proteomes; UP000008220; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR024478; HlyB_4HB_MCP.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF12729; 4HB_MCP_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008220};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        189..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          212..264
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          276..534
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   570 AA;  63741 MW;  1494BCCB7F9F398A CRC64;
     MNFYKNLKLS TRLIIGSFIA IFSMVIIGSM GILNMNKINK STNYLYYTTI KSINSINKID
     KNLLNIYEAE KVMMYIKDQN EISKLIKEID NFMQENLKQI EIYKSTIDDN EERKLFTEFE
     NKLHKYRESG QAYEKLILSG RADEAMIKSS NIAKERNDMR TKLDKLVQLN EEWAKEVIED
     NTDTYKKSFL TIISIIVALV ILSGLVVGLI GKNIKKSLAS IKGLSDRLSN YDLSEPIIIT
     SNDEFGQIGK GLNRVQENIS SLIKNIIDST REMNASSDEL SSTVQKMASK FQNINTSTKE
     INSQVQETSA TAEQISASVQ EVDSSVSVLS GKAIDGSNSA IEIKTRAAEV EHNSKIASES
     SRDLYIQMEK EVLKDIEQGK VVEHIKVMAD TIASIAEQTN LLALNAAIEA ARAGEQGKGF
     AVVAEEVRKL AEQSSAAVGN VKFTIEKVQE SFENLSSNSS KLLKFMNDRV VSQFETFVHV
     GEQYEKDGVF VNNMSEELAT MTEEVSATIN QVSEAVQSMA DMAQKSSENL NSIQQNVNES
     TKVMEQVEYT AQTQAELSEK LNNMVEKFTI
//