A0Q276 (A0Q276_CLONN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Sensory transduction histidine kinase EMBL ABK61427.1

Gene names

Ordered Locus Names:

NT01CX_0224

Organism

Clostridium novyi (strain NT) [Complete proteome] [HAMAP] EMBL ABK61427.1

Taxonomic identifier

386415 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium › Clostridium novyi

Protein attributes

Sequence length	1666 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities

Contains 1 histidine kinase domain. SAAS SAAS004358

Ontologies

Keywords
Ligand	ATP-binding SAAS SAAS005467 Nucleotide-binding
Molecular function	Kinase SAAS SAAS004358 EMBL ABK61427.1 Transferase
PTM	Phosphoprotein SAAS SAAS004358
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	phosphorelay signal transduction system Inferred from electronic annotation. Source: GOC signal transduction by phosphorylation Inferred from electronic annotation. Source: GOC
Cellular_component	membrane Inferred from electronic annotation. Source: InterPro
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphorelay sensor kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0Q276 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: DCDACDBACA495969	FASTA	1,666	194,241
	10 20 30 40 50 60 MEYYKKKGEV ILEEFICNKK DMSIKEFLKN ALKIVDAVSE VHKEGMIYKY LNPKNIILDI 70 80 90 100 110 120 NGQLKLMEST FMCRDINYNL RYMAPEQIGR IKKNVDFSTD HYSLGVIFYR MLTGKLPIEV 130 140 150 160 170 180 DDEIKLSYCN TNKKPVSPKK IKNTIPLVIS KIVMKLLEKD SEERYKSIYG IKVDLNKCYK 190 200 210 220 230 240 SLIFSGEVYN FPLGERDVSD KLKFTNKIYG REKEIETIMD KYHKACRGTL QCVAISGDSG 250 260 270 280 290 300 MGKTIIGSEI SKRIVKEGGI LLSSKCKKYN NNVPYYPLIE CTRMLINKIL MEDEEKISYL 310 320 330 340 350 360 KKEILKELGS NAQIITKFVP EAEFLIGKQP PLEERGFIES KSRFNMVIIR FTRIILNMKK 370 380 390 400 410 420 PIAIFLEDIQ WLDESSLYII RKFLLNKENK YLFILTTLRT TDVENNKFLK EIVEQDDVLN 430 440 450 460 470 480 IKLESLNKYS IENLICDTLY CSKEEVKELV KFINIRTDGN PFFIKTSIES MYLNGVLKFD 490 500 510 520 530 540 YTNNKWAWNM KLLKNMKIEN SIFEIIIRKI NQLSSDTKEI LKLGSCIGQE FSLKCISEIL 550 560 570 580 590 600 NTSINVIFNN IIPAITEGVI ILDEYATKNP KNKVYRFAHS QIQMQIYDGI SKEKKEKYHL 610 620 630 640 650 660 SIGRYFYNEY SKNNLESKLF EVVNQLNKGR NLITNYDEIY KLIKLNLNIG LKEKEAGIHQ 670 680 690 700 710 720 LALGYFEVAY NLLEENSWEK DYDLTYAVNI ELAECEFMNK NFEKAEELFK IILKNVKTPW 730 740 750 760 770 780 ETIKIYNMKV CIYTYFKQMD KAIETGINAL KVLGIHISEK PSFIKICCET LKFRLMKKSI 790 800 810 820 830 840 VNNNRYIIKE NGIMEELKKL FFNMSFLAIL YDKNLFILLV LKEMQINLYN TKSNNEIFTN 850 860 870 880 890 900 INYEFLIMNL LKNYGKSYEM ALNDLKKCYK KIDTIIYAKA YTVFANFMVL WSNDYNTTLD 910 920 930 940 950 960 HLCKCYNICM DTGENSCAAF TLNNMITVFL MKGENLLEIK NKIKVYIDDI EKSNFDDIRD 970 980 990 1000 1010 1020 NLVLNRRIID VLIADEENEV LSAKDYIIER EYLGMYTYKI MLNYILGNYE DSIEIMKARE 1030 1040 1050 1060 1070 1080 NNNNNLNEVY IDSLYYIFAC LTNIKLLEKC PESQKRNYTK KIRSYMKYIK KKVNINSDIF 1090 1100 1110 1120 1130 1140 LSMYILVKAE FYRVINKGYK SERLYDEAIK IATKNNMINN IALISEIAGD HYKSQGNITV 1150 1160 1170 1180 1190 1200 SKLYLIQAYT FYKRWGCRLK VKDLENKYPE IFKKNSSYNK NGYFLVSDIV NKLYIDDIFQ 1210 1220 1230 1240 1250 1260 CSIKMKRNKY EFMKFIKAFQ SISGEIVLEN LLKELMINLI ASVEAERGCL ILNKNNKLFI 1270 1280 1290 1300 1310 1320 EAEGEVDDIC SVMENPIALE EYTKISKLLV NYVVRTKKSI LLDDGKCEDI VFDDKYIVDN 1330 1340 1350 1360 1370 1380 KVKSILCTPI IAKEKIIGII YLENRFSSGI FNEKRLSIVE LIASQAAISI ENAFMYEEIN 1390 1400 1410 1420 1430 1440 TLNKELKNTV DERTKLLNES IKYEEMRTEF FANISHELRT PLNVIFSGYQ MLNVLLENED 1450 1460 1470 1480 1490 1500 LENKEKVDKY MGTVKQNCYR LVRLINNLID ITKIDSGFFK LNMINVNIVN IVETITLSVA 1510 1520 1530 1540 1550 1560 QYIESKGINL IFDTFIEEKT MACDVDKIER IILNLLSNAV KFTNKGGNIF VTMKEEDNNI 1570 1580 1590 1600 1610 1620 VISVKDDGIG IPKEKQSIIF DRFIQVDKSL SRNREGSGIG LALVKSIVEL HDGNITLKSK 1630 1640 1650 1660 LGRGSEFIIK LPCKVLEKQN KTAKKYTNAN SNKIEKIMIE FSDIYS

References

[1]

"The genome and transcriptomes of the anti-tumor agent Clostridium novyi-NT." Bettegowda C., Huang X., Lin J., Cheong I., Kohli M., Szabo S.A., Zhang X., Diaz L.A. Jr., Velculescu V.E., Parmigiani G., Kinzler K.W., Vogelstein B., Zhou S. Nat. Biotechnol. 24:1573-1580(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NT.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000382 Genomic DNA. Translation: ABK61427.1.
RefSeq	YP_878728.1. NC_008593.1.
3D structure databases
ProteinModelPortal	A0Q276.
ModBase	Search...
Protein-protein interaction databases
STRING	386415.NT01CX_0224.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABK61427; ABK61427; NT01CX_0224.
GeneID	4541180.
KEGG	cno:NT01CX_0224.
PATRIC	19480994. VBICloNov112828_1762.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0642.
OMA	AMNDASN.
Enzyme and pathway databases
BioCyc	CNOV386415:GH98-1865-MONOMER.
Family and domain databases
Gene3D	1.10.287.130. 1 hit. 3.30.565.10. 1 hit.
InterPro	IPR003018. GAF. IPR003594. HATPase_ATP-bd. IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR004358. Sig_transdc_His_kin-like_C. IPR003661. Sig_transdc_His_kin_sub1_dim/P. IPR005467. Sig_transdc_His_kinase_core. IPR009082. Sig_transdc_His_kinase_dimeric. [Graphical view]
Pfam	PF13492. GAF_3. 1 hit. PF02518. HATPase_c. 1 hit. PF00512. HisKA. 1 hit. PF00069. Pkinase. 1 hit. [Graphical view]
PRINTS	PR00344. BCTRLSENSOR.
SMART	SM00065. GAF. 1 hit. SM00387. HATPase_c. 1 hit. SM00388. HisKA. 1 hit. [Graphical view]
SUPFAM	SSF55874. ATP_bd_ATPase. 1 hit. SSF47384. His_kin_homodim. 1 hit. SSF56112. Kinase_like. 1 hit.
PROSITE	PS50109. HIS_KIN. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A0Q276_CLONN

Accession

Primary (citable) accession number: A0Q276

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	May 1, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)