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Protein

Histidine kinase

Gene

NT01CX_0224

Organism
Clostridium novyi (strain NT)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphorelay sensor kinase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotationImported, Transferase

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciCNOV386415:GH98-1791-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Histidine kinaseSAAS annotation (EC:2.7.13.3SAAS annotation)
Gene namesi
Ordered Locus Names:NT01CX_0224Imported
OrganismiClostridium novyi (strain NT)Imported
Taxonomic identifieri386415 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000008220 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

PhosphoproteinSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi386415.NT01CX_0224.

Family & Domainsi

Sequence similaritiesi

Contains histidine kinase domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG0642.
OMAiLLMIEYS.
OrthoDBiEOG6HTNS7.

Family and domain databases

Gene3Di1.10.287.130. 1 hit.
3.30.450.40. 1 hit.
3.30.565.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR003661. EnvZ-like_dim/P.
IPR003018. GAF.
IPR029016. GAF_dom_like.
IPR003594. HATPase_C.
IPR011009. Kinase-like_dom.
IPR027417. P-loop_NTPase.
IPR000719. Prot_kinase_dom.
IPR004358. Sig_transdc_His_kin-like_C.
IPR005467. Sig_transdc_His_kinase_core.
IPR009082. Sig_transdc_His_kinase_dimeric.
[Graphical view]
PfamiPF13492. GAF_3. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00065. GAF. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF55781. SSF55781. 1 hit.
SSF55874. SSF55874. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0Q276-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEYYKKKGEV ILEEFICNKK DMSIKEFLKN ALKIVDAVSE VHKEGMIYKY
60 70 80 90 100
LNPKNIILDI NGQLKLMEST FMCRDINYNL RYMAPEQIGR IKKNVDFSTD
110 120 130 140 150
HYSLGVIFYR MLTGKLPIEV DDEIKLSYCN TNKKPVSPKK IKNTIPLVIS
160 170 180 190 200
KIVMKLLEKD SEERYKSIYG IKVDLNKCYK SLIFSGEVYN FPLGERDVSD
210 220 230 240 250
KLKFTNKIYG REKEIETIMD KYHKACRGTL QCVAISGDSG MGKTIIGSEI
260 270 280 290 300
SKRIVKEGGI LLSSKCKKYN NNVPYYPLIE CTRMLINKIL MEDEEKISYL
310 320 330 340 350
KKEILKELGS NAQIITKFVP EAEFLIGKQP PLEERGFIES KSRFNMVIIR
360 370 380 390 400
FTRIILNMKK PIAIFLEDIQ WLDESSLYII RKFLLNKENK YLFILTTLRT
410 420 430 440 450
TDVENNKFLK EIVEQDDVLN IKLESLNKYS IENLICDTLY CSKEEVKELV
460 470 480 490 500
KFINIRTDGN PFFIKTSIES MYLNGVLKFD YTNNKWAWNM KLLKNMKIEN
510 520 530 540 550
SIFEIIIRKI NQLSSDTKEI LKLGSCIGQE FSLKCISEIL NTSINVIFNN
560 570 580 590 600
IIPAITEGVI ILDEYATKNP KNKVYRFAHS QIQMQIYDGI SKEKKEKYHL
610 620 630 640 650
SIGRYFYNEY SKNNLESKLF EVVNQLNKGR NLITNYDEIY KLIKLNLNIG
660 670 680 690 700
LKEKEAGIHQ LALGYFEVAY NLLEENSWEK DYDLTYAVNI ELAECEFMNK
710 720 730 740 750
NFEKAEELFK IILKNVKTPW ETIKIYNMKV CIYTYFKQMD KAIETGINAL
760 770 780 790 800
KVLGIHISEK PSFIKICCET LKFRLMKKSI VNNNRYIIKE NGIMEELKKL
810 820 830 840 850
FFNMSFLAIL YDKNLFILLV LKEMQINLYN TKSNNEIFTN INYEFLIMNL
860 870 880 890 900
LKNYGKSYEM ALNDLKKCYK KIDTIIYAKA YTVFANFMVL WSNDYNTTLD
910 920 930 940 950
HLCKCYNICM DTGENSCAAF TLNNMITVFL MKGENLLEIK NKIKVYIDDI
960 970 980 990 1000
EKSNFDDIRD NLVLNRRIID VLIADEENEV LSAKDYIIER EYLGMYTYKI
1010 1020 1030 1040 1050
MLNYILGNYE DSIEIMKARE NNNNNLNEVY IDSLYYIFAC LTNIKLLEKC
1060 1070 1080 1090 1100
PESQKRNYTK KIRSYMKYIK KKVNINSDIF LSMYILVKAE FYRVINKGYK
1110 1120 1130 1140 1150
SERLYDEAIK IATKNNMINN IALISEIAGD HYKSQGNITV SKLYLIQAYT
1160 1170 1180 1190 1200
FYKRWGCRLK VKDLENKYPE IFKKNSSYNK NGYFLVSDIV NKLYIDDIFQ
1210 1220 1230 1240 1250
CSIKMKRNKY EFMKFIKAFQ SISGEIVLEN LLKELMINLI ASVEAERGCL
1260 1270 1280 1290 1300
ILNKNNKLFI EAEGEVDDIC SVMENPIALE EYTKISKLLV NYVVRTKKSI
1310 1320 1330 1340 1350
LLDDGKCEDI VFDDKYIVDN KVKSILCTPI IAKEKIIGII YLENRFSSGI
1360 1370 1380 1390 1400
FNEKRLSIVE LIASQAAISI ENAFMYEEIN TLNKELKNTV DERTKLLNES
1410 1420 1430 1440 1450
IKYEEMRTEF FANISHELRT PLNVIFSGYQ MLNVLLENED LENKEKVDKY
1460 1470 1480 1490 1500
MGTVKQNCYR LVRLINNLID ITKIDSGFFK LNMINVNIVN IVETITLSVA
1510 1520 1530 1540 1550
QYIESKGINL IFDTFIEEKT MACDVDKIER IILNLLSNAV KFTNKGGNIF
1560 1570 1580 1590 1600
VTMKEEDNNI VISVKDDGIG IPKEKQSIIF DRFIQVDKSL SRNREGSGIG
1610 1620 1630 1640 1650
LALVKSIVEL HDGNITLKSK LGRGSEFIIK LPCKVLEKQN KTAKKYTNAN
1660
SNKIEKIMIE FSDIYS
Length:1,666
Mass (Da):194,241
Last modified:January 9, 2007 - v1
Checksum:iDCDACDBACA495969
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000382 Genomic DNA. Translation: ABK61427.1.
RefSeqiYP_878728.1. NC_008593.1.

Genome annotation databases

EnsemblBacteriaiABK61427; ABK61427; NT01CX_0224.
GeneIDi4541180.
KEGGicno:NT01CX_0224.
PATRICi19480994. VBICloNov112828_1762.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000382 Genomic DNA. Translation: ABK61427.1.
RefSeqiYP_878728.1. NC_008593.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi386415.NT01CX_0224.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABK61427; ABK61427; NT01CX_0224.
GeneIDi4541180.
KEGGicno:NT01CX_0224.
PATRICi19480994. VBICloNov112828_1762.

Phylogenomic databases

eggNOGiCOG0642.
OMAiLLMIEYS.
OrthoDBiEOG6HTNS7.

Enzyme and pathway databases

BioCyciCNOV386415:GH98-1791-MONOMER.

Family and domain databases

Gene3Di1.10.287.130. 1 hit.
3.30.450.40. 1 hit.
3.30.565.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR003661. EnvZ-like_dim/P.
IPR003018. GAF.
IPR029016. GAF_dom_like.
IPR003594. HATPase_C.
IPR011009. Kinase-like_dom.
IPR027417. P-loop_NTPase.
IPR000719. Prot_kinase_dom.
IPR004358. Sig_transdc_His_kin-like_C.
IPR005467. Sig_transdc_His_kinase_core.
IPR009082. Sig_transdc_His_kinase_dimeric.
[Graphical view]
PfamiPF13492. GAF_3. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00065. GAF. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF55781. SSF55781. 1 hit.
SSF55874. SSF55874. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NTImported.

Entry informationi

Entry nameiA0Q276_CLONN
AccessioniPrimary (citable) accession number: A0Q276
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: April 1, 2015
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.