ID   A0Q1N1_CLONN            Unreviewed;       664 AA.
AC   A0Q1N1;
DT   09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2007, sequence version 1.
DT   27-MAR-2024, entry version 79.
DE   SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:ABK62237.1};
GN   OrderedLocusNames=NT01CX_0024 {ECO:0000313|EMBL:ABK62237.1};
OS   Clostridium novyi (strain NT).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=386415 {ECO:0000313|EMBL:ABK62237.1, ECO:0000313|Proteomes:UP000008220};
RN   [1] {ECO:0000313|EMBL:ABK62237.1, ECO:0000313|Proteomes:UP000008220}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NT {ECO:0000313|EMBL:ABK62237.1,
RC   ECO:0000313|Proteomes:UP000008220};
RX   PubMed=17115055; DOI=10.1038/nbt1256;
RA   Bettegowda C., Huang X., Lin J., Cheong I., Kohli M., Szabo S.A., Zhang X.,
RA   Diaz L.A. Jr., Velculescu V.E., Parmigiani G., Kinzler K.W., Vogelstein B.,
RA   Zhou S.;
RT   "The genome and transcriptomes of the anti-tumor agent Clostridium novyi-
RT   NT.";
RL   Nat. Biotechnol. 24:1573-1580(2006).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; CP000382; ABK62237.1; -; Genomic_DNA.
DR   RefSeq; WP_011722527.1; NC_008593.1.
DR   AlphaFoldDB; A0Q1N1; -.
DR   STRING; 386415.NT01CX_0024; -.
DR   KEGG; cno:NT01CX_0024; -.
DR   PATRIC; fig|386415.7.peg.1564; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_19_9; -.
DR   Proteomes; UP000008220; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd18773; PDC1_HK_sensor; 1.
DR   CDD; cd12912; PDC2_MCP_like; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008220};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          305..359
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          378..635
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   COILED          568..602
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   664 AA;  73794 MW;  601AA4A4F375E082 CRC64;
     MKQNKRSLYK QMLILLFVSI LVPLLLVTGI NYHIMEGEQK EDFNQIAISS IKTINQYINH
     LNNSSKESVN MLSLEPNAKV ILDGSDHEQW LNNNLKSFLE SHEGITAVYM GAKNGKVIAQ
     PEQNISEDFD VTKTQWYKKA IENPNEAILT DPYISRGKDK EYEVTYAKAV KDGSGNIVGV
     IGLDIKLRYI DKITKNMRIG KNGFAMVIDK NGTILSHRDS NKIGKKDKDA LDILNSKEDV
     FEQYINGTKM VIFKGVEKSN GYITVGLIPK KELTDTIFKS AIINIIIAFL SIGVAIWGAS
     RFTKKKIINP INYVVNILND FSNGDFTKEI DKKSGLTIEI EYMVDAINLT RDNVVNIVKN
     IKNACYNLKE NSNTLLSITE QSNVASDEIA KAIQQIADGS VSQSEKLNES VHLTEILNDI
     VVNSITNSEK MMKASEEVRN VSDEGKSLLK NLEGTFNEGK EANLEVIREV KNLGDKSKEI
     EEITEVIKGI TEQTKLLALN ASIEAARAGE AGKGFAVVAE EVTKLAEQSS NSAIKIKNVI
     DDIKSSMIEV FNKLDNAIKF SSKTGEDINV TEKNFNDIRE SIEILKENID NVNSDLKDIK
     KNKDSVLYNI GKISSVAQET AATSEEVSAS SEEQASGLQE IVLSAEKLNN LSEKLEDIIE
     VFKI
//