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A0Q140

- URK_CLONN

UniProt

A0Q140 - URK_CLONN

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Protein

Uridine kinase

Gene

udk

Organism
Clostridium novyi (strain NT)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + uridine = ADP + UMP.UniRule annotation
ATP + cytidine = ADP + CMP.UniRule annotation

Pathwayi

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi11 – 188ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. phosphotransferase activity, alcohol group as acceptor Source: InterPro
  3. uridine kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. CTP salvage Source: UniProtKB-UniPathway
  2. UMP salvage Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCNOV386415:GH98-1401-MONOMER.
UniPathwayiUPA00574; UER00637.
UPA00579; UER00640.

Names & Taxonomyi

Protein namesi
Recommended name:
Uridine kinaseUniRule annotation (EC:2.7.1.48UniRule annotation)
Alternative name(s):
Cytidine monophosphokinaseUniRule annotation
Uridine monophosphokinaseUniRule annotation
Gene namesi
Name:udkUniRule annotation
Ordered Locus Names:NT01CX_2269
OrganismiClostridium novyi (strain NT)
Taxonomic identifieri386415 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000008220: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 208208Uridine kinasePRO_1000200512Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi386415.NT01CX_2269.

Structurei

3D structure databases

ProteinModelPortaliA0Q140.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uridine kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0572.
HOGENOMiHOG000262756.
KOiK00876.
OMAiHFGDRSI.
OrthoDBiEOG6KMBCH.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00551. Uridine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR006083. PRK/URK.
IPR026008. Uridine_kinase_.
IPR000764. Uridine_kinase_like.
[Graphical view]
PANTHERiPTHR10285:SF6. PTHR10285:SF6. 1 hit.
PfamiPF00485. PRK. 1 hit.
[Graphical view]
PRINTSiPR00988. URIDINKINASE.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00235. udk. 1 hit.

Sequencei

Sequence statusi: Complete.

A0Q140-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MMRPILIGIT GGTGSGKSTV ANEIYESFKD DCIAIIEQDS YYKDQSHLTF
60 70 80 90 100
EDRIKTNYDH PNAFDTELLV EHLKELSKGN TINKPIYDFK EHTRKKEVVE
110 120 130 140 150
VKAKDIIIVE GIMILQDVEL RNLLDIKIYV DTDDDVRIIR RILRDIKERG
160 170 180 190 200
RTIDSVVDQY LGVVKPMHSQ FIEPTKKYAD IIIPEGGQNK VAIDIMVSKI

KQILSENK
Length:208
Mass (Da):23,908
Last modified:January 9, 2007 - v1
Checksum:iFE54519BBBA38E99
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000382 Genomic DNA. Translation: ABK61121.1.
RefSeqiWP_011722338.1. NC_008593.1.
YP_878342.1. NC_008593.1.

Genome annotation databases

EnsemblBacteriaiABK61121; ABK61121; NT01CX_2269.
GeneIDi4541853.
KEGGicno:NT01CX_2269.
PATRICi19480204. VBICloNov112828_1372.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000382 Genomic DNA. Translation: ABK61121.1 .
RefSeqi WP_011722338.1. NC_008593.1.
YP_878342.1. NC_008593.1.

3D structure databases

ProteinModelPortali A0Q140.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 386415.NT01CX_2269.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABK61121 ; ABK61121 ; NT01CX_2269 .
GeneIDi 4541853.
KEGGi cno:NT01CX_2269.
PATRICi 19480204. VBICloNov112828_1372.

Phylogenomic databases

eggNOGi COG0572.
HOGENOMi HOG000262756.
KOi K00876.
OMAi HFGDRSI.
OrthoDBi EOG6KMBCH.

Enzyme and pathway databases

UniPathwayi UPA00574 ; UER00637 .
UPA00579 ; UER00640 .
BioCyci CNOV386415:GH98-1401-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00551. Uridine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR006083. PRK/URK.
IPR026008. Uridine_kinase_.
IPR000764. Uridine_kinase_like.
[Graphical view ]
PANTHERi PTHR10285:SF6. PTHR10285:SF6. 1 hit.
Pfami PF00485. PRK. 1 hit.
[Graphical view ]
PRINTSi PR00988. URIDINKINASE.
SUPFAMi SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00235. udk. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NT.

Entry informationi

Entry nameiURK_CLONN
AccessioniPrimary (citable) accession number: A0Q140
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: January 9, 2007
Last modified: October 29, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3