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Reviewed, UniProtKB/Swiss-Prot A0Q0Z5 (ACKA_CLONN)

Last modified June 16, 2009. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Acetate kinase
    EC=2.7.2.1
Alternative name(s):
    Acetokinase
Gene names
Name: ackA
Ordered Locus Names: NT01CX_2224
OrganismClostridium novyi (strain NT) [Complete proteome] [HAMAP]
Taxonomic identifier386415 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium

Protein attributes

Sequence length401 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

phosphorylation

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 401401Acetate kinase HAMAP MF_00020
PRO_1000002224

Sequences

Sequence LengthMass (Da)Tools
A0Q0Z5-1 [UniParc].

Last modified January 9, 2007. Version 1.
Checksum: BADD5534819CF006

FASTA40143,982
        10         20         30         40         50         60 
MKILVINCGS SSLKYQLIDM TSEQPIAQGL VERIGIEGSV LTHKVNGKKY KIEEEMKDHK 

        70         80         90        100        110        120 
KAIELVLNAL VNEEYGVIKN MEEISAVGHR VVHGGEKYAE SVLIDSEVME ALEDFVKLAP 

       130        140        150        160        170        180 
LHNPPNIIGI NACKELMSST PMVAVFDTAF HQTLPDYAYM YSLPYDLYEK HGIRKYGFHG 

       190        200        210        220        230        240 
TSHKYVSAMA AKVLGKNIED LKLITCHLGN GSSLAAVKNG KCVDTSMGFT PLAGLTMGTR 

       250        260        270        280        290        300 
CGDIDPAIVT FLIKELNYSV DEVNKIMNKE SGVLGISGIS SDFRDILKAA SEGNERAELA 

       310        320        330        340        350        360 
LNIFKNKVIQ YIGAYTAVMG GVDAIIFTAG VGENSEPIRK RIISDLGFLG IKLDEEKNKV 

       370        380        390        400 
MGETETISTE DSKVKVLAIP TNEELMIARD TKEIVEKNNI K 

« Hide

References

[1]"The genome and transcriptomes of the anti-tumor agent Clostridium novyi-NT."
Bettegowda C., Huang X., Lin J., Cheong I., Kohli M., Szabo S.A., Zhang X., Diaz L.A. Jr., Velculescu V.E., Parmigiani G., Kinzler K.W., Vogelstein B., Zhou S.
Nat. Biotechnol. 24:1573-1580(2006) [PubMed: 17115055] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

CP000382 Genomic DNA. Translation: ABK60556.1.
RefSeqYP_878297.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID4541780.
GenomeReviewsGene locus NT01CX_2224 in contig CP000382_GR.
KEGGcno:NT01CX_2224.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAA0Q0Z5. IDMEREV.

Family and domain databases

HAMAPMF_00020.
[Tree]
InterProIPR000890. Acetate_kin.
IPR004372. AckA.
[Graphical view]
PANTHERPTHR21060. Acetate_kin. 1 hit.
PTHR21060:SF11. AckA. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. ackA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA_CLONN
AccessionPrimary (citable) accession number: A0Q0Z5
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 9, 2007
Last modified: June 16, 2009
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents