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Protein

Anti-sigma F factor

Gene

spoIIAB

Organism
Clostridium novyi (strain NT)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.UniRule annotation

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Biological processi

Sporulation

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Anti-sigma F factorUniRule annotation (EC:2.7.11.1UniRule annotation)
Alternative name(s):
Stage II sporulation protein ABUniRule annotation
Gene namesi
Name:spoIIABUniRule annotation
Ordered Locus Names:NT01CX_1805
OrganismiClostridium novyi (strain NT)
Taxonomic identifieri386415 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000008220 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001308111 – 143Anti-sigma F factorAdd BLAST143

Proteomic databases

PRIDEiA0PZS6.

Interactioni

Protein-protein interaction databases

STRINGi386415.NT01CX_1805.

Structurei

3D structure databases

ProteinModelPortaliA0PZS6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the anti-sigma-factor family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108ZBE. Bacteria.
COG2172. LUCA.
HOGENOMiHOG000269931.
KOiK06379.
OMAiHAYEDKI.
OrthoDBiPOG091H0LCB.

Family and domain databases

Gene3Di3.30.565.10. 1 hit.
HAMAPiMF_00637. Anti_sigma_F. 1 hit.
InterProiIPR010194. Anti-sigma_F.
IPR003594. HATPase_C.
[Graphical view]
PfamiPF13581. HATPase_c_2. 1 hit.
[Graphical view]
SMARTiSM00387. HATPase_c. 1 hit.
[Graphical view]
SUPFAMiSSF55874. SSF55874. 1 hit.
TIGRFAMsiTIGR01925. spIIAB. 1 hit.

Sequencei

Sequence statusi: Complete.

A0PZS6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGNKMKMEF LSKSQNESFA RVAVAAFISQ LDPTMEEITD VKTAVSEAVT
60 70 80 90 100
NSIIHGYGDR EDGIVKIQCE IFEKDITIIV EDDGIGIEDV KQAMTPLYTS
110 120 130 140
RPDLERSGMG FTVMETFMDE LRVESTEKNG TRIIMKKKLK SIE
Length:143
Mass (Da):16,049
Last modified:January 9, 2007 - v1
Checksum:i0EDFD9BDC9094189
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000382 Genomic DNA. Translation: ABK61462.1.
RefSeqiWP_011721883.1. NC_008593.1.

Genome annotation databases

EnsemblBacteriaiABK61462; ABK61462; NT01CX_1805.
KEGGicno:NT01CX_1805.
PATRICi19479276. VBICloNov112828_0908.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000382 Genomic DNA. Translation: ABK61462.1.
RefSeqiWP_011721883.1. NC_008593.1.

3D structure databases

ProteinModelPortaliA0PZS6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi386415.NT01CX_1805.

Proteomic databases

PRIDEiA0PZS6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABK61462; ABK61462; NT01CX_1805.
KEGGicno:NT01CX_1805.
PATRICi19479276. VBICloNov112828_0908.

Phylogenomic databases

eggNOGiENOG4108ZBE. Bacteria.
COG2172. LUCA.
HOGENOMiHOG000269931.
KOiK06379.
OMAiHAYEDKI.
OrthoDBiPOG091H0LCB.

Family and domain databases

Gene3Di3.30.565.10. 1 hit.
HAMAPiMF_00637. Anti_sigma_F. 1 hit.
InterProiIPR010194. Anti-sigma_F.
IPR003594. HATPase_C.
[Graphical view]
PfamiPF13581. HATPase_c_2. 1 hit.
[Graphical view]
SMARTiSM00387. HATPase_c. 1 hit.
[Graphical view]
SUPFAMiSSF55874. SSF55874. 1 hit.
TIGRFAMsiTIGR01925. spIIAB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSP2AB_CLONN
AccessioniPrimary (citable) accession number: A0PZS6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: January 9, 2007
Last modified: November 2, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.