ID   DEOC_CLONN              Reviewed;         222 AA.
AC   A0PYX5;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   16-JUN-2009, entry version 16.
DE   RecName: Full=Deoxyribose-phosphate aldolase;
DE            EC=4.1.2.4;
DE   AltName: Full=Phosphodeoxyriboaldolase;
DE            Short=Deoxyriboaldolase;
DE            Short=DERA;
GN   Name=deoC; OrderedLocusNames=NT01CX_1496;
OS   Clostridium novyi (strain NT).
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=386415;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17115055; DOI=10.1038/nbt1256;
RA   Bettegowda C., Huang X., Lin J., Cheong I., Kohli M., Szabo S.A.,
RA   Zhang X., Diaz L.A. Jr., Velculescu V.E., Parmigiani G., Kinzler K.W.,
RA   Vogelstein B., Zhou S.;
RT   "The genome and transcriptomes of the anti-tumor agent Clostridium
RT   novyi-NT.";
RL   Nat. Biotechnol. 24:1573-1580(2006).
CC   -!- CATALYTIC ACTIVITY: 2-deoxy-D-ribose 5-phosphate = D-
CC       glyceraldehyde 3-phosphate + acetaldehyde.
CC   -!- PATHWAY: Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate
CC       degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-
CC       deoxy-D-ribose 1-phosphate: step 2/2.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the deoC/fbaB aldolase family. DeoC type 1
CC       subfamily.
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DR   EMBL; CP000382; ABK60834.1; -; Genomic_DNA.
DR   RefSeq; YP_877577.1; -.
DR   GeneID; 4539848; -.
DR   GenomeReviews; CP000382_GR; NT01CX_1496.
DR   KEGG; cno:NT01CX_1496; -.
DR   OMA; A0PYX5; AKMIDHT.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004139; F:deoxyribose-phosphate aldolase activity; IEA:HAMAP.
DR   GO; GO:0016052; P:carbohydrate catabolic process; IEA:HAMAP.
DR   GO; GO:0009264; P:deoxyribonucleotide catabolic process; IEA:InterPro.
DR   HAMAP; MF_00114; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR011343; DeoC.
DR   InterPro; IPR002915; DeoC/AroFGH_arch.
DR   Gene3D; G3DSA:3.20.20.70; Aldolase_TIM; 1.
DR   PANTHER; PTHR10889; DeoC; 1.
DR   Pfam; PF01791; DeoC; 1.
DR   PIRSF; PIRSF001357; DeoC; 1.
DR   TIGRFAMs; TIGR00126; deoC; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Lyase; Schiff base.
FT   CHAIN         1    222       Deoxyribose-phosphate aldolase.
FT                                /FTId=PRO_1000015312.
FT   ACT_SITE    152    152       Schiff-base intermediate with
FT                                acetaldehyde (By similarity).
FT   ACT_SITE    181    181       By similarity.
SQ   SEQUENCE   222 AA;  23571 MW;  B92EC5EFA4DECF35 CRC64;
     MNLNKYIDHT LLKPQATEED IKKICKEAKE YNFASVCVNT CYTSLVSKEL EGTDVTTCVV
     VGFPLGATTT ETKAFEAKQA IEQGAGEVDM VINVGALKSK KYDYVKKDIE AVVEAAKGKA
     LVKVILENCL LEKEEIVKAC ELSKEAGADF VKTSTGFSTG GAKVEDVKLM RETVGPDMGV
     KASGAVRTKE DAEAVIAAGA NRIGASSSIA IVEGTKSENA GY
//