Reviewed, UniProtKB/Swiss-Prot A0PY73 (GLGA_CLONN)

Names and origin

Protein names

Recommended name:
    Glycogen synthase
    EC=2.4.1.21
Alternative name(s):
    Starch [bacterial glycogen] synthase

Gene names

Name:	glgA
Ordered Locus Names:	NT01CX_1242

Organism

Clostridium novyi (strain NT) [Complete proteome] [HAMAP]

Taxonomic identifier

386415 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	479 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Synthesizes alpha-1,4-glucan chains using ADP-glucose. HAMAP MF_00484
Catalytic activity	ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP MF_00484
Pathway	Glycan biosynthesis; glycogen biosynthesis. HAMAP MF_00484
Sequence similarities	Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
Biological process	Glycogen biosynthesis
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycogen biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	starch synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 479	479	Glycogen synthase HAMAP MF_00484		PRO_1000014348
Sites
	Binding site	15	1	ADP-glucose By similarity

Sequences

	Sequence		Length	Mass (Da)
	A0PY73-1 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: D7B2DDD0B1B138FB	FASTA	479	55,396
	10 20 30 40 50 60 MNILFATSEA FPFIKTGGLG DVSYALPKAL KRKGTDIRVI LPKYSSIPQE YADNMRKVAE 70 80 90 100 110 120 FTVGVGWRSQ YCGLLELEKD GVKFYFIDNE YYFKRNSAYA QMDDGERFSF FSRAILESIN 130 140 150 160 170 180 HISDFTPDVL HCNDWHTAMT IPMLRDQYFN NPKLNNIKTV YTIHNLKYQG RFGKEILWEL 190 200 210 220 230 240 LGFGDEYFSE DKFKYYDSIS FMKAGIVYAD AITTVSPTYA EEIKTEYYGE GLNGLLQSRS 250 260 270 280 290 300 KDLYGILNGI DTDVNNPSTD MFLFDKYDVN NLEAKARNKE KLQEMLHLPK NRDIPMIGIV 310 320 330 340 350 360 ARLEEQKGFE LIKEVIEELL QENIQLVVLG TGDQRYEDMF KFFAWKYPDK LSANIYFDGG 370 380 390 400 410 420 LAQKIYAASD MFLMPSRFEP CGIGQLIALR YGSVPIVRET GGLNDTVFSY NEFTGEGNGF 430 440 450 460 470 SFTSFNARDM LYTIKRAIGF YYDKDVWSKL VQRGMNGDYS WEKAAEKYMR VYSNILHKW

References

[1]

"The genome and transcriptomes of the anti-tumor agent Clostridium novyi-NT." Bettegowda C., Huang X., Lin J., Cheong I., Kohli M., Szabo S.A., Zhang X., Diaz L.A. Jr., Velculescu V.E., Parmigiani G., Kinzler K.W., Vogelstein B., Zhou S. Nat. Biotechnol. 24:1573-1580(2006) [PubMed: 17115055] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000382 Genomic DNA. Translation: ABK61836.1.
RefSeq	YP_877325.1.
3D structure databases
SMR	A0PY73. Positions 1-476.
ModBase	Search...
Protein-protein interaction databases
STRING	A0PY73.
Genome annotation databases
GeneID	4540561.
GenomeReviews	Gene locus NT01CX_1242 in contig CP000382_GR.
KEGG	cno:NT01CX_1242.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0297.
HOGENOM	HBG596384.
OMA	LFAVSEC.
Family and domain databases
HAMAP	MF_00484. Glycogen_synth. [Tree]
InterPro	IPR011835. GlgA. IPR001296. Glyco_trans_1. IPR013534. Starch_synth_cat_dom. [Graphical view]
Pfam	PF08323. Glyco_transf_5. 1 hit. PF00534. Glycos_transf_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR02095. glgA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLGA_CLONN

Accession

Primary (citable) accession number: A0PY73

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	January 9, 2007
Last modified:	February 9, 2010
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)