ID   A0PY27_CLONN            Unreviewed;       574 AA.
AC   A0PY27;
DT   09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2007, sequence version 1.
DT   27-MAR-2024, entry version 79.
DE   SubName: Full=Membrane associated methyl-accepting chemotaxis protein with HAMP domain {ECO:0000313|EMBL:ABK61393.1};
GN   OrderedLocusNames=NT01CX_1196 {ECO:0000313|EMBL:ABK61393.1};
OS   Clostridium novyi (strain NT).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=386415 {ECO:0000313|EMBL:ABK61393.1, ECO:0000313|Proteomes:UP000008220};
RN   [1] {ECO:0000313|EMBL:ABK61393.1, ECO:0000313|Proteomes:UP000008220}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NT {ECO:0000313|EMBL:ABK61393.1,
RC   ECO:0000313|Proteomes:UP000008220};
RX   PubMed=17115055; DOI=10.1038/nbt1256;
RA   Bettegowda C., Huang X., Lin J., Cheong I., Kohli M., Szabo S.A., Zhang X.,
RA   Diaz L.A. Jr., Velculescu V.E., Parmigiani G., Kinzler K.W., Vogelstein B.,
RA   Zhou S.;
RT   "The genome and transcriptomes of the anti-tumor agent Clostridium novyi-
RT   NT.";
RL   Nat. Biotechnol. 24:1573-1580(2006).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; CP000382; ABK61393.1; -; Genomic_DNA.
DR   RefSeq; WP_011721287.1; NC_008593.1.
DR   AlphaFoldDB; A0PY27; -.
DR   STRING; 386415.NT01CX_1196; -.
DR   KEGG; cno:NT01CX_1196; -.
DR   PATRIC; fig|386415.7.peg.307; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_27_9; -.
DR   Proteomes; UP000008220; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR024478; HlyB_4HB_MCP.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF12729; 4HB_MCP_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008220};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        192..215
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          216..268
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          287..524
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   574 AA;  63994 MW;  60C14B0E43992AB1 CRC64;
     MDFLKKISVK KKMIFSYSAL LMLMIISGVI GVVSAKKLND NSKQMYFKSL QSIEYIQEIK
     NNIDEEATCI LNIIYNEDLN QNDRNNIYKH ITVDLKNKNQ ELFEKYEKIP FTEEEKRDYN
     EFKHELENYR NVRGDILTLV NNGNINGAKQ IFASKIKPIR EKTESKLNAI NDMNETQAKI
     SDEENRKVFQ NIIFISSAVT IVGIILALVL AIIMIRDIIS SLNRIRAYAR RLSEYDFSTP
     IVVRGTDELC MTAVDLNSAQ KNVNNLVKQI YLDAETMGAM SEELSATVEE ITSKVITIDE
     ATKEINKGIE EFSASTEELN ASVEEVNSSI EELATSSTEG SNNSNVAKGK AKEVQEYLQD
     AIKETNSIYE ERQQKIIKAI EDGKVVSEIR VMADSIAQIA EQTNLLALNA AIEAARAGEQ
     GKGFAVVADE IRKLAEQSAE SVLVIKNTIT QVQSAFGNLS DNGNQLLDFM NTKVKELLDS
     SLSVSKQYYD DSDYISTMTE NFASMTEEIN ATTNQITGAV QNIALGAQDA AEHTGDILSG
     IDETTKAMNE IAKTSENQAS IAQKLNELVG KFKI
//