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Protein
Submitted name:

Conserved hypothetical transmembrane protein

Gene

MUL_4971

Organism
Mycobacterium ulcerans (strain Agy99)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Protein family/group databases

CAZyiGT85. Glycosyltransferase Family 85.

Names & Taxonomyi

Protein namesi
Submitted name:
Conserved hypothetical transmembrane proteinImported
Gene namesi
Ordered Locus Names:MUL_4971Imported
OrganismiMycobacterium ulcerans (strain Agy99)Imported
Taxonomic identifieri362242 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000000765 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei43 – 6523HelicalSequence analysisAdd
BLAST
Transmembranei77 – 9721HelicalSequence analysisAdd
BLAST
Transmembranei163 – 18018HelicalSequence analysisAdd
BLAST
Transmembranei187 – 20216HelicalSequence analysisAdd
BLAST
Transmembranei284 – 30118HelicalSequence analysisAdd
BLAST
Transmembranei313 – 33422HelicalSequence analysisAdd
BLAST
Transmembranei364 – 38219HelicalSequence analysisAdd
BLAST
Transmembranei394 – 41522HelicalSequence analysisAdd
BLAST
Transmembranei421 – 44020HelicalSequence analysisAdd
BLAST
Transmembranei452 – 46918HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3838Sequence analysisAdd
BLAST
Chaini39 – 654616Sequence analysisPRO_5002628840Add
BLAST

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini10 – 454445AftA_NInterPro annotationAdd
BLAST
Domaini472 – 648177AftA_CInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOGENOMiHOG000054313.
KOiK13686.
OMAiYPAGWFW.
OrthoDBiEOG6G4VQS.

Family and domain databases

InterProiIPR020959. ArabinofuranosylTrfase_AftA_C.
IPR020963. ArabinofuranosylTrfase_AftA_N.
[Graphical view]
PfamiPF12249. AftA_C. 1 hit.
PF12250. AftA_N. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0PWY4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRNALATLGQ MAAAVLVAVT VAVVALSAIS QVQWPAFPSS NQLHALTTVG
60 70 80 90 100
QVGCLAGLLG AGWAWRRGGR LRRPAQLGGL VFVSAFTVVT LGMPLGATRL
110 120 130 140 150
YLFGISVDQQ FRTEYLTRLT DSPALHDMIY IGLPPFYPPG WFWIGGRAAA
160 170 180 190 200
LTGSPAWEMF KPWAITSIAV AVAVALVLWW RMIRFEYALL VTIATTAVTL
210 220 230 240 250
AYSSPEPYAA MITVLLPPVL VLTWSGLRAG APPAPERHAS VAPDAESHAD
260 270 280 290 300
VTLGAEAARG WGAVVGAGIF LGFAATWYTL LVAYSAFTVT LMAALLVVSR
310 320 330 340 350
WRRGGLRAAV DPLRRLAVIA VIAATIASTT WLPYLLRAAR DPVSDTGSAQ
360 370 380 390 400
HYLPADGAEL TFPMLQFSLL GALCMLGTLW LVVRARSSTR AGALAIGVLA
410 420 430 440 450
VYLWSLLSML TTLARTTLLS FRLQPTLTVL LATAGIFGFL EGTRALTVRS
460 470 480 490 500
RAALPVAAAI GLAGAIAFSQ DIPDVLRPDL TIAYTDTDGY GERGDQRPPG
510 520 530 540 550
SEKYYSTIDT TIRKVTGKPR DQVVVMTADY SFLSYYPYWG FQGLTSHYAN
560 570 580 590 600
PLAQFDKRAA QIESWGKIKT SDEFVQALDK LLWPAPTVFL MRRGAGPGSG
610 620 630 640 650
ASYTLRLAED VYPNQPNVRR YTVDLKAALF ADPRFTVETI GPFVLAIRKP

AASA
Length:654
Mass (Da):70,359
Last modified:January 9, 2007 - v1
Checksum:i50A1176EDBF543BB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000325 Genomic DNA. Translation: ABL06853.1.

Genome annotation databases

EnsemblBacteriaiABL06853; ABL06853; MUL_4971.
KEGGimul:MUL_4971.
PATRICi18177872. VBIMycUlc37413_5731.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000325 Genomic DNA. Translation: ABL06853.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGT85. Glycosyltransferase Family 85.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABL06853; ABL06853; MUL_4971.
KEGGimul:MUL_4971.
PATRICi18177872. VBIMycUlc37413_5731.

Phylogenomic databases

HOGENOMiHOG000054313.
KOiK13686.
OMAiYPAGWFW.
OrthoDBiEOG6G4VQS.

Family and domain databases

InterProiIPR020959. ArabinofuranosylTrfase_AftA_C.
IPR020963. ArabinofuranosylTrfase_AftA_N.
[Graphical view]
PfamiPF12249. AftA_C. 1 hit.
PF12250. AftA_N. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer."
    Stinear T.P., Seemann T., Pidot S., Frigui W., Reysset G., Garnier T., Meurice G., Simon D., Bouchier C., Ma L., Tichit M., Porter J.L., Ryan J., Johnson P.D., Davies J.K., Jenkin G.A., Small P.L., Jones L.M.
    , Tekaia F., Laval F., Daffe M., Parkhill J., Cole S.T.
    Genome Res. 17:192-200(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Agy99Imported.

Entry informationi

Entry nameiA0PWY4_MYCUA
AccessioniPrimary (citable) accession number: A0PWY4
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: March 16, 2016
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.