A0PWP3 (A0PWP3_MYCUA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Bifunctional Mta/Sah nucleosidase Mtn EMBL ABL06762.1

Gene names

Name:	mtn EMBL ABL06762.1
Ordered Locus Names:	MUL_4862

Organism

Mycobacterium ulcerans (strain Agy99) [Complete proteome] [HAMAP]

Taxonomic identifier

362242 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	251 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity

S-adenosyl-L-homocysteine + H2O = S-(5-deoxy-D-ribos-5-yl)-L-homocysteine + adenine. SAAS SAAS010049 S-methyl-5'-thioadenosine + H2O = S-methyl-5-thio-D-ribose + adenine. SAAS SAAS010049

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Methionine biosynthesis SAAS SAAS010049
Molecular function	Hydrolase SAAS SAAS010049
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	L-methionine salvage from methylthioadenosine Inferred from electronic annotation. Source: InterPro nucleoside catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	adenosylhomocysteine nucleosidase activity Inferred from electronic annotation. Source: InterPro methylthioadenosine nucleosidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0PWP3 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 7630ABEF99C0E2D5	FASTA	251	26,906
	10 20 30 40 50 60 MTIGVICAIP QELAYLRTNL VATDQQEIAR ICFYAGQLGD RRVVLTAAGM GKVNAGLVAT 70 80 90 100 110 120 LLADRFDCHT VIFTGVAGGL DPALSIGDIV IADRVVQHDC GLLTDDGLQP YQPGHVPFIK 130 140 150 160 170 180 PTEQLGYRVD PELLDRVKHR LEDFTLPALS AAAGGGARPP RINYGTILTG DQYLHSARTR 190 200 210 220 230 240 DQLYNDFAGM AIEMEGGALA QVCESFAISW LVIRAPSDLA GAGSGLDFNR FVDEVSVSSA 250 RILLHLLSVV D

References

[1]

"Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer." Stinear T.P., Seemann T., Pidot S., Frigui W., Reysset G., Garnier T., Meurice G., Simon D., Bouchier C., Ma L., Tichit M., Porter J.L., Ryan J., Johnson P.D.R., Davies J.K., Jenkin G.A., Small P.L.C., Jones L.M. , Tekaia F., Laval F., Daffe M., Parkhill J., Cole S.T. Genome Res. 17:192-200(2007) [PubMed: 17210928] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000325 Genomic DNA. Translation: ABL06762.1.
RefSeq	YP_908233.1. NC_008611.1.
3D structure databases
ProteinModelPortal	A0PWP3.
ModBase	Search...
Protein-protein interaction databases
STRING	A0PWP3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000073804; EBMYCP00000071809; EBMYCG00000073799.
GeneID	4549626.
GenomeReviews	Gene locus MUL_4862 in contig CP000325_GR.
KEGG	mul:MUL_4862.
PATRIC	18177631. VBIMycUlc37413_5611.
Organism-specific databases
GenoList	MUL_4862.
CMR	Search...
Phylogenomic databases
eggNOG	COG0775.
GeneTree	EBGT00050000018357.
HOGENOM	HBG367723.
OMA	LEHFPTM.
PhylomeDB	A0PWP3.
ProtClustDB	CLSK790256.
Family and domain databases
InterPro	IPR010049. MTA_SAH_Nsdase. IPR018017. Nucleoside_phosphorylase. IPR000845. Nucleoside_phosphorylase_d. [Graphical view]
KO	K01243.
PANTHER	PTHR21234. PNP_UDP. 1 hit. PTHR21234:SF6. PTHR21234:SF6. 1 hit.
Pfam	PF01048. PNP_UDP_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR01704. MTA/SAH-Nsdase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A0PWP3_MYCUA

Accession

Primary (citable) accession number: A0PWP3

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)