A0PWF4 (A0PWF4_MYCUA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Serine/threonine-protein kinase transcriptional regulatory protein PknK_3 EMBL ABL06673.1

Gene names

Name:	pknK_3 EMBL ABL06673.1
Ordered Locus Names:	MUL_4753 EMBL ABL06673.1

Organism

Mycobacterium ulcerans (strain Agy99) [Complete proteome] [HAMAP] EMBL ABL06673.1

Taxonomic identifier

362242 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium ulcerans

Protein attributes

Sequence length	979 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the protein kinase superfamily. RuleBase RU000305

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000304 Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase RuleBase RU000305 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	ADP binding Inferred from electronic annotation. Source: InterPro ATP binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine kinase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0PWF4 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: C0FCFF73955465B3	FASTA	979	105,193
	10 20 30 40 50 60 MDGFADAAEV GRGGFGVVYR CRQVDLDRVV AIKVLTIDLD ENRPRFEREQ RAMAKLTGHP 70 80 90 100 110 120 NIVSVLQIGE TRDGHPYLVM PYCRRGSVQT EISRLGRLSL ADILQLGVAL AAGLESAHRL 130 140 150 160 170 180 DILHRDIKPA NVLLTDFGEP ALTDFGLAHM AGGFRTATGL FTASPAFTAS ELARGGEPDR 190 200 210 220 230 240 ASDVYGVGAT LFCALTGHPP FERRKGESVI AQILRVANDP VPDLAEYDVA EDVASVVNRA 250 260 270 280 290 300 LSRDPAARPT MVELGEAIQS LQAAHGQAVD AMALEGGKRS TSVSSESAWH VSARQTRGNL 310 320 330 340 350 360 PAKLAGFVGR QAELAELGAL ISTSRPVTLT GVGGVGKTSL AVQAAGEHVS HFHDGVWLVD 370 380 390 400 410 420 IGELSDGALL AGLAARMLGI RDQGARPLTE VLTDALAERD ALVIFDGCEH VIDHAAQLID 430 440 450 460 470 480 TLLQGCPQLH ILATSRELLG IGGEAVLALS PLPYPDAASV SSRSSVARYD AVALFVERAR 490 500 510 520 530 540 TARPGFTLTQ RNAAAVARIC ERLDGLPLAI ELAAARLRAV SVEQIADRLS DRFGLLTRGQ 550 560 570 580 590 600 RGAPTRQQTL SYCIDWSYDH CTPIQQQLWA RLSVFAGSFD LDAAQYVAPQ DMDADDLLDE 610 620 630 640 650 660 LCALVDKSIL IRTEDDGAVR FRLLSTMREY GNSRIDAEQY QGLQQSHFDW CERLVTQAHL 670 680 690 700 710 720 EWFSRKQVDW IHRLRSELPN IEEALQFGLE KAPESVLLMA AKLRNLFVVS GKLQVGRLWV 730 740 750 760 770 780 ERALSTTTSA QPSGARIAAL AALAMFAVLQ TDWPTAQSCV AQAHEHGAAV PDPIAESLLG 790 800 810 820 830 840 VARGLGALLQ GQVEQVQTDA EQGLAAGDFE LQVLGMWLMP LRHLAVGDPE PALRWAEKAH 850 860 870 880 890 900 SVSESRVEVQ MRTYSLSALA VSHLMLGDTG SAERSLREGL KLCQVIDDPW SGASYLEGLA 910 920 930 940 950 960 WTAGANGNLR RAVVLMAAAA ALSRSSGAGS TVIALVGSMH QQCERAAREE LSDAVFETAR 970 VEGESLSFDD AADVALTEP

References

[1]

"Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer." Stinear T.P., Seemann T., Pidot S.J.A., Frigui W., Reysset G., Garnier T., Meurice G., Simon D., Bouchier C., Ma L., Tichit M., Porter J.L., Ryan J.E., Johnson P.D.R., Davies J.K., Jenkin G.A., Small P.L.C., Jones L.M. , Tekaia F., Laval F., Daffe M., Parkhill J., Cole S.T. Genome Res. 17:192-200(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Agy99 EMBL ABL06673.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000325 Genomic DNA. Translation: ABL06673.1.
RefSeq	YP_908144.1. NC_008611.1.
3D structure databases
ProteinModelPortal	A0PWF4.
ModBase	Search...
Protein-protein interaction databases
STRING	362242.MUL_4753.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABL06673; ABL06673; MUL_4753.
GeneID	4550890.
KEGG	mul:MUL_4753.
PATRIC	18177390. VBIMycUlc37413_5491.
Organism-specific databases
GenoList	MUL_4753.
CMR	Search...
Phylogenomic databases
eggNOG	COG0515.
HOGENOM	HOG000053696.
OMA	RSSVARY.
ProtClustDB	CLSK776800.
Family and domain databases
Gene3D	1.25.40.10. 1 hit.
InterPro	IPR011009. Kinase-like_dom. IPR002182. NB-ARC. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR008271. Ser/Thr_kinase_AS. IPR011990. TPR-like_helical. [Graphical view]
Pfam	PF00931. NB-ARC. 1 hit. PF00069. Pkinase. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A0PWF4_MYCUA

Accession

Primary (citable) accession number: A0PWF4

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	May 1, 2013
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)