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A0PWF4

- A0PWF4_MYCUA

UniProt

A0PWF4 - A0PWF4_MYCUA

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Protein
Submitted name:

Serine/threonine-protein kinase transcriptional regulatory protein PknK_3

Gene
pknK_3, MUL_4753
Organism
Mycobacterium ulcerans (strain Agy99)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. ADP binding Source: InterPro
  2. ATP binding Source: UniProtKB-KW
  3. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseUniRule annotation, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Serine/threonine-protein kinase transcriptional regulatory protein PknK_3Imported
Gene namesi
Name:pknK_3Imported
Ordered Locus Names:MUL_4753Imported
OrganismiMycobacterium ulcerans (strain Agy99)Imported
Taxonomic identifieri362242 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000000765: Chromosome

Organism-specific databases

GenoListiMUL_4753.

Interactioni

Protein-protein interaction databases

STRINGi362242.MUL_4753.

Structurei

3D structure databases

ProteinModelPortaliA0PWF4.

Family & Domainsi

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000053696.
OMAiRSSVARY.
OrthoDBiEOG6B35XT.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR011009. Kinase-like_dom.
IPR002182. NB-ARC.
IPR027417. P-loop_NTPase.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
IPR011990. TPR-like_helical.
[Graphical view]
PfamiPF00931. NB-ARC. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0PWF4-1 [UniParc]FASTAAdd to Basket

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MDGFADAAEV GRGGFGVVYR CRQVDLDRVV AIKVLTIDLD ENRPRFEREQ    50
RAMAKLTGHP NIVSVLQIGE TRDGHPYLVM PYCRRGSVQT EISRLGRLSL 100
ADILQLGVAL AAGLESAHRL DILHRDIKPA NVLLTDFGEP ALTDFGLAHM 150
AGGFRTATGL FTASPAFTAS ELARGGEPDR ASDVYGVGAT LFCALTGHPP 200
FERRKGESVI AQILRVANDP VPDLAEYDVA EDVASVVNRA LSRDPAARPT 250
MVELGEAIQS LQAAHGQAVD AMALEGGKRS TSVSSESAWH VSARQTRGNL 300
PAKLAGFVGR QAELAELGAL ISTSRPVTLT GVGGVGKTSL AVQAAGEHVS 350
HFHDGVWLVD IGELSDGALL AGLAARMLGI RDQGARPLTE VLTDALAERD 400
ALVIFDGCEH VIDHAAQLID TLLQGCPQLH ILATSRELLG IGGEAVLALS 450
PLPYPDAASV SSRSSVARYD AVALFVERAR TARPGFTLTQ RNAAAVARIC 500
ERLDGLPLAI ELAAARLRAV SVEQIADRLS DRFGLLTRGQ RGAPTRQQTL 550
SYCIDWSYDH CTPIQQQLWA RLSVFAGSFD LDAAQYVAPQ DMDADDLLDE 600
LCALVDKSIL IRTEDDGAVR FRLLSTMREY GNSRIDAEQY QGLQQSHFDW 650
CERLVTQAHL EWFSRKQVDW IHRLRSELPN IEEALQFGLE KAPESVLLMA 700
AKLRNLFVVS GKLQVGRLWV ERALSTTTSA QPSGARIAAL AALAMFAVLQ 750
TDWPTAQSCV AQAHEHGAAV PDPIAESLLG VARGLGALLQ GQVEQVQTDA 800
EQGLAAGDFE LQVLGMWLMP LRHLAVGDPE PALRWAEKAH SVSESRVEVQ 850
MRTYSLSALA VSHLMLGDTG SAERSLREGL KLCQVIDDPW SGASYLEGLA 900
WTAGANGNLR RAVVLMAAAA ALSRSSGAGS TVIALVGSMH QQCERAAREE 950
LSDAVFETAR VEGESLSFDD AADVALTEP 979
Length:979
Mass (Da):105,193
Last modified:January 9, 2007 - v1
Checksum:iC0FCFF73955465B3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000325 Genomic DNA. Translation: ABL06673.1.
RefSeqiYP_908144.1. NC_008611.1.

Genome annotation databases

EnsemblBacteriaiABL06673; ABL06673; MUL_4753.
GeneIDi4550890.
KEGGimul:MUL_4753.
PATRICi18177390. VBIMycUlc37413_5491.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000325 Genomic DNA. Translation: ABL06673.1 .
RefSeqi YP_908144.1. NC_008611.1.

3D structure databases

ProteinModelPortali A0PWF4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 362242.MUL_4753.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABL06673 ; ABL06673 ; MUL_4753 .
GeneIDi 4550890.
KEGGi mul:MUL_4753.
PATRICi 18177390. VBIMycUlc37413_5491.

Organism-specific databases

GenoListi MUL_4753.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000053696.
OMAi RSSVARY.
OrthoDBi EOG6B35XT.

Family and domain databases

Gene3Di 1.25.40.10. 1 hit.
3.40.50.300. 1 hit.
InterProi IPR011009. Kinase-like_dom.
IPR002182. NB-ARC.
IPR027417. P-loop_NTPase.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
IPR011990. TPR-like_helical.
[Graphical view ]
Pfami PF00931. NB-ARC. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer."
    Stinear T.P., Seemann T., Pidot S., Frigui W., Reysset G., Garnier T., Meurice G., Simon D., Bouchier C., Ma L., Tichit M., Porter J.L., Ryan J., Johnson P.D., Davies J.K., Jenkin G.A., Small P.L., Jones L.M.
    , Tekaia F., Laval F., Daffe M., Parkhill J., Cole S.T.
    Genome Res. 17:192-200(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Agy99Imported.

Entry informationi

Entry nameiA0PWF4_MYCUA
AccessioniPrimary (citable) accession number: A0PWF4
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: May 14, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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