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A0PW77 (A0PW77_MYCUA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribosomal RNA small subunit methyltransferase I HAMAP MF_01877
EC=2.1.1.198 HAMAP MF_01877
Alternative name(s):
16S rRNA 2'-O-ribose C1402 methyltransferase HAMAP MF_01877
rRNA (cytidine-2'-O-)-methyltransferase RsmI HAMAP MF_01877
Gene names
Name:rsmI HAMAP MF_01877
Ordered Locus Names:MUL_4662
OrganismMycobacterium ulcerans (strain Agy99) [Complete proteome] [HAMAP]
Taxonomic identifier362242 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length284 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA By similarity. HAMAP MF_01877

Catalytic activity

S-adenosyl-L-methionine + cytosine(1402) in 16S rRNA = S-adenosyl-L-homocysteine + 2'-O-methylcytosine(1402) in 16S rRNA. HAMAP MF_01877

Subcellular location

Cytoplasm By similarity HAMAP MF_01877.

Sequence similarities

Belongs to the methyltransferase superfamily. RsmI family. HAMAP MF_01877

Ontologies

Keywords
   Biological processrRNA processing HAMAP MF_01877
   Cellular componentCytoplasm HAMAP MF_01877
   LigandS-adenosyl-L-methionine HAMAP MF_01877
   Molecular functionMethyltransferase HAMAP MF_01877
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processenzyme-directed rRNA 2'-O-methylation

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionrRNA (cytosine-2'-O-)-methyltransferase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A0PW77 [UniParc].

Last modified January 9, 2007. Version 1.
Checksum: 8E7B31EC3A212C39

FASTA28429,685
        10         20         30         40         50         60 
MTVGRLLLGA TPLGQPSDAS ARLIDALTSA DVVAAEDTRR VLTLAKALDI SIGGRVVSLF 

        70         80         90        100        110        120 
DRVEALRVGA LVEAIEAGAT VLVVSDAGMP IINDPGYRLV AACIEAGISV TCLPGPSAVT 

       130        140        150        160        170        180 
TALVVSGLAS DKFCFEGFAP RKSGARRAWL ASLAEEPRTC VFFESPRRLA ACLRDAVEQL 

       190        200        210        220        230        240 
GGSRRAAVCR ELTKVHEEVR RGSLGELADW AADGVLGEIT VVLAGAAPLH VDLQPLVAEV 

       250        260        270        280 
ENLVAGGIRV KDACSEVATG HQGIRTRELY DAVQLARRET DAAP

« Hide

References

[1]"Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer."
Stinear T.P., Seemann T., Pidot S., Frigui W., Reysset G., Garnier T., Meurice G., Simon D., Bouchier C., Ma L., Tichit M., Porter J.L., Ryan J., Johnson P.D.R., Davies J.K., Jenkin G.A., Small P.L.C., Jones L.M. expand/collapse author list , Tekaia F., Laval F., Daffe M., Parkhill J., Cole S.T.
Genome Res. 17:192-200(2007) [PubMed: 17210928] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000325 Genomic DNA. Translation: ABL06596.1.
RefSeqYP_908067.1. NC_008611.1.

3D structure databases

ProteinModelPortalA0PW77.
ModBaseSearch...

Protein-protein interaction databases

STRINGA0PW77.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000076632; EBMYCP00000074637; EBMYCG00000076627.
GeneID4554506.
GenomeReviewsGene locus MUL_4662 in contig CP000325_GR.
KEGGmul:MUL_4662.
PATRIC18177179. VBIMycUlc37413_5387.

Organism-specific databases

GenoListMUL_4662.
CMRSearch...

Phylogenomic databases

eggNOGCOG0313.
GeneTreeEBGT00050000017256.
HOGENOMHBG529058.
OMAIASDRFC.
PhylomeDBA0PW77.
ProtClustDBCLSK790887.

Family and domain databases

HAMAPMF_01877. 16SrRNA_methyltr_I.
[Tree]
InterProIPR000878. 4pyrrol_Mease.
IPR014777. 4pyrrole_Mease_sub1.
IPR014776. 4pyrrole_Mease_sub2.
IPR008189. rRNA_ssu_MeTfrase_I.
IPR018063. SAM_MeTrfase_RsmI_CS.
[Graphical view]
Gene3DG3DSA:3.40.1010.10. 4pyrrole_Mease_sub1. 1 hit.
G3DSA:3.30.950.10. 4pyrrole_Mease_sub2. 1 hit.
KOK07056.
PANTHERPTHR21091:SF18. PTHR21091:SF18. 1 hit.
PfamPF00590. TP_methylase. 1 hit.
[Graphical view]
PIRSFPIRSF005917. MTase_YraL. 1 hit.
SUPFAMSSF53790. Cor/por_Metransf. 1 hit.
TIGRFAMsTIGR00096. TIGR00096. 1 hit.
PROSITEPS01296. RSMI. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA0PW77_MYCUA
AccessionPrimary (citable) accession number: A0PW77
Entry history
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info