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A0PW04 (A0PW04_MYCUA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Pyrroline-5-carboxylate reductase RuleBase RU003903
EC=1.5.1.2 RuleBase RU003903
Gene names
Name:proC EMBL ABL06523.1
Ordered Locus Names:MUL_4570
OrganismMycobacterium ulcerans (strain Agy99) [Complete proteome] [HAMAP]
Taxonomic identifier362242 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length294 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-proline + NAD(P)+ = 1-pyrroline-5-carboxylate + NAD(P)H. RuleBase RU003903

Pathway

Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1. RuleBase RU003903

Sequence similarities

Belongs to the pyrroline-5-carboxylate reductase family. RuleBase RU003903

Sequences

Sequence LengthMass (Da)Tools
A0PW04 [UniParc].

Last modified January 9, 2007. Version 1.
Checksum: 60C67C12290A221E

FASTA29430,077
        10         20         30         40         50         60 
MLSGMPRIAI IGGGSIGEAL LSGLLRAGRQ VKDLVVAERV PERAKYLAST YSVLVTSAKD 

        70         80         90        100        110        120 
AAESASLVVV AVKPGDVDSV MGDLSAVVAA AESYSGEQVF VTVAAGVTTS YFESKLPAGT 

       130        140        150        160        170        180 
PVVRAMPNAA ALVSAGVTAL AKGRFVTPEQ LEEVSALFDS VGVVLTVPEQ QLDAVTALSG 

       190        200        210        220        230        240 
SGPAYFLLMV EALVDAGVAA GLSRQVATDL TAQTMAGSAA MLLERMDQDR RGAAEPLGLR 

       250        260        270        280        290 
LDTSPAQLRA SVTSPGGTTA AALRELEREG FRGAVDAAVQ AAKSRSEQLR ITSE

« Hide

References

[1]"Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer."
Stinear T.P., Seemann T., Pidot S., Frigui W., Reysset G., Garnier T., Meurice G., Simon D., Bouchier C., Ma L., Tichit M., Porter J.L., Ryan J., Johnson P.D.R., Davies J.K., Jenkin G.A., Small P.L.C., Jones L.M. expand/collapse author list , Tekaia F., Laval F., Daffe M., Parkhill J., Cole S.T.
Genome Res. 17:192-200(2007) [PubMed: 17210928] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000325 Genomic DNA. Translation: ABL06523.1.
RefSeqYP_907994.1. NC_008611.1.

3D structure databases

ProteinModelPortalA0PW04.
ModBaseSearch...

Protein-protein interaction databases

STRINGA0PW04.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000075821; EBMYCP00000073826; EBMYCG00000075816.
GeneID4551457.
GenomeReviewsGene locus MUL_4570 in contig CP000325_GR.
KEGGmul:MUL_4570.
PATRIC18176979. VBIMycUlc37413_5290.

Organism-specific databases

GenoListMUL_4570.
CMRSearch...

Phylogenomic databases

eggNOGCOG0345.
GeneTreeEBGT00050000017740.
HOGENOMHBG726602.
OMARTFNEHQ.
ProtClustDBPRK11880.

Family and domain databases

InterProIPR008927. 6-PGluconate_DH_C-like.
IPR016040. NAD(P)-bd_dom.
IPR004455. NADP_OxRdtase_F420.
IPR000304. Pyrroline-COOH_reductase.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK00286.
PANTHERPTHR11645. P5CR. 1 hit.
PfamPF03807. F420_oxidored. 1 hit.
[Graphical view]
PIRSFPIRSF000193. Pyrrol-5-carb_rd. 1 hit.
SUPFAMSSF48179. 6DGDH_C_like. 1 hit.
TIGRFAMsTIGR00112. ProC. 1 hit.
PROSITEPS00521. P5CR. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA0PW04_MYCUA
AccessionPrimary (citable) accession number: A0PW04
Entry history
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: December 14, 2011
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info