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Protein
Submitted name:

ATP-dependent DNA ligase LigC

Gene

ligC

Organism
Mycobacterium ulcerans (strain Agy99)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. DNA ligase (ATP) activity Source: InterPro

GO - Biological processi

  1. DNA recombination Source: InterPro
  2. DNA repair Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LigaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-dependent DNA ligase LigCImported
Gene namesi
Name:ligCImported
Ordered Locus Names:MUL_4340Imported
OrganismiMycobacterium ulcerans (strain Agy99)Imported
Taxonomic identifieri362242 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000000765: Chromosome

Organism-specific databases

GenoListiMUL_4340.

Interactioni

Protein-protein interaction databases

STRINGi362242.MUL_4340.

Structurei

3D structure databases

ProteinModelPortaliA0PVH5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG1793.
HOGENOMiHOG000222508.
KOiK01971.
OMAiHERTADC.
OrthoDBiEOG63NMFT.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
PROSITEiPS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0PVH5-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MDLPVMPPIS PMLAKAVKTI PADASYEPKW DGFRSICFRD NDEVELGSRN
60 70 80 90 100
ERPLTRYFPE LVAAVRAELP RRCVLDGEIV IATGHGLDFE ALQQRIHHAD
110 120 130 140 150
SRVRMLAEHI PASFIAFDLL ALGDDDYTTR PFVERRAALV EAVGSGPSIH
160 170 180 190 200
VTPATTDQAT ARRWFEEFEG AGLDGVIAKP LAVTYQPDKC VMFKLKHERT
210 220 230 240 250
ADCVLAGYRL HKSGGDVIGS LLLGLYQDDG QLASVGVIGA FPMAERRRLF
260 270 280 290 300
TELQELVTSF DDHPWNWAAH QSGERTPRKN EFSRWNAGKD LSFVPLRPER
310 320 330 340 350
VVEVRYDHME GPRFRHTAQF NRWRPDRDPR SCTYAQLEQP LMFNLDDIVA

GLGPRCGH
Length:358
Mass (Da):40,376
Last modified:January 9, 2007 - v1
Checksum:i46F12B555106E2EC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000325 Genomic DNA. Translation: ABL06344.1.
RefSeqiWP_011741946.1. NC_008611.1.
YP_907815.1. NC_008611.1.

Genome annotation databases

EnsemblBacteriaiABL06344; ABL06344; MUL_4340.
GeneIDi4550500.
KEGGimul:MUL_4340.
PATRICi18176443. VBIMycUlc37413_5026.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000325 Genomic DNA. Translation: ABL06344.1.
RefSeqiWP_011741946.1. NC_008611.1.
YP_907815.1. NC_008611.1.

3D structure databases

ProteinModelPortaliA0PVH5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi362242.MUL_4340.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABL06344; ABL06344; MUL_4340.
GeneIDi4550500.
KEGGimul:MUL_4340.
PATRICi18176443. VBIMycUlc37413_5026.

Organism-specific databases

GenoListiMUL_4340.

Phylogenomic databases

eggNOGiCOG1793.
HOGENOMiHOG000222508.
KOiK01971.
OMAiHERTADC.
OrthoDBiEOG63NMFT.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
PROSITEiPS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer."
    Stinear T.P., Seemann T., Pidot S., Frigui W., Reysset G., Garnier T., Meurice G., Simon D., Bouchier C., Ma L., Tichit M., Porter J.L., Ryan J., Johnson P.D.R., Davies J.K., Jenkin G.A., Small P.L.C., Jones L.M.
    , Tekaia F., Laval F., Daffe M., Parkhill J., Cole S.T.
    Genome Res. 17:192-200(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Agy99Imported.

Entry informationi

Entry nameiA0PVH5_MYCUA
AccessioniPrimary (citable) accession number: A0PVH5
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: January 7, 2015
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.