A0PUN9 (A0PUN9_MYCUA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Sulfate adenylyltransferase subunit 2 HAMAP MF_00064
EC=2.7.7.4 HAMAP MF_00064

Alternative name(s):
ATP-sulfurylase small subunit HAMAP MF_00064
Sulfate adenylate transferase HAMAP MF_00064

Gene names

Name:	cysD HAMAP MF_00064 EMBL ABL06058.1
Ordered Locus Names:	MUL_3996

Organism

Mycobacterium ulcerans (strain Agy99) [Complete proteome] [HAMAP]

Taxonomic identifier

362242 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	310 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + sulfate = diphosphate + adenylyl sulfate. HAMAP MF_00064 SAAS SAAS002500
Pathway	Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3. HAMAP MF_00064
Subunit structure	Heterodimer composed of CysD, the smaller subunit, and CysN By similarity. HAMAP MF_00064
Sequence similarities	Belongs to the PAPS reductase family. CysD subfamily. HAMAP MF_00064

Ontologies

Keywords
Ligand	ATP-binding HAMAP MF_00064 SAAS SAAS002500 Nucleotide-binding
Molecular function	Nucleotidyltransferase HAMAP MF_00064 SAAS SAAS002500 EMBL ABL06058.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	sulfate assimilation Inferred from electronic annotation. Source: HAMAP sulfate reduction Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW sulfate adenylyltransferase (ATP) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0PUN9 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 24265B41166411D8	FASTA	310	34,917
	10 20 30 40 50 60 MTTSGVTTGP AVGQYELSHL RSLEAEAMHI IREVAAEFER PVLLFSGGKD SIVMLHLAIK 70 80 90 100 110 120 AFRPGRLPFP VMHVDTGHNF DEVIATRDEL VAASGVRLVV ASVQDDIDAG RVVETFPSRN 130 140 150 160 170 180 SMQTVTLLRA IRENRFDAAF GGARRDEEKA RAKERVFSFR DEFGQWDPKA QRPELWNLYN 190 200 210 220 230 240 GRHHKGEHIR VFPLSNWTEF DIWSYIGAEH ITLPSIYFAH RRKVFKRDGM LLAVDRHMQP 250 260 270 280 290 300 GADEPVFEAT VRFRTVGDVT CTGCVESEAA TVAEVIAETA VARLTERGAT RADDRISESG 310 MEDRKRQGYF

References

[1]

"Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer." Stinear T.P., Seemann T., Pidot S., Frigui W., Reysset G., Garnier T., Meurice G., Simon D., Bouchier C., Ma L., Tichit M., Porter J.L., Ryan J., Johnson P.D.R., Davies J.K., Jenkin G.A., Small P.L.C., Jones L.M. , Tekaia F., Laval F., Daffe M., Parkhill J., Cole S.T. Genome Res. 17:192-200(2007) [PubMed: 17210928] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000325 Genomic DNA. Translation: ABL06058.1.
RefSeq	YP_907529.1. NC_008611.1.
3D structure databases
ProteinModelPortal	A0PUN9.
SMR	A0PUN9. Positions 16-219.
ModBase	Search...
Protein-protein interaction databases
STRING	A0PUN9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000074018; EBMYCP00000072023; EBMYCG00000074013.
GeneID	4550736.
GenomeReviews	Gene locus MUL_3996 in contig CP000325_GR.
KEGG	mul:MUL_3996.
PATRIC	18175672. VBIMycUlc37413_4647.
Organism-specific databases
GenoList	MUL_3996.
CMR	Search...
Phylogenomic databases
eggNOG	COG0175.
GeneTree	EBGT00050000016335.
HOGENOM	HBG758022.
OMA	NYPEVIQ.
PhylomeDB	A0PUN9.
ProtClustDB	PRK05253.
Family and domain databases
HAMAP	MF_00064. Sulf_adenylyltr_sub2. [Tree]
InterPro	IPR002500. PAPS_reduct. IPR014729. Rossmann-like_a/b/a_fold. IPR011784. SO4_adenylTrfase_ssu. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 2 hits.
KO	K00957.
Pfam	PF01507. PAPS_reduct. 1 hit. [Graphical view]
PIRSF	PIRSF002936. CysDAde_trans. 1 hit.
TIGRFAMs	TIGR02039. CysD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A0PUN9_MYCUA

Accession

Primary (citable) accession number: A0PUN9

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)