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Protein
Submitted name:

Transmembrane serine/threonine-protein kinase E PknE

Gene

pknE

Organism
Mycobacterium ulcerans (strain Agy99)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseUniRule annotation, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Transmembrane serine/threonine-protein kinase E PknEImported
Gene namesi
Name:pknEImported
Ordered Locus Names:MUL_3180Imported
OrganismiMycobacterium ulcerans (strain Agy99)Imported
Taxonomic identifieri362242 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
ProteomesiUP000000765 Componenti: Chromosome

Organism-specific databases

GenoListiMUL_3180.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliA0PST1.
SMRiA0PST1. Positions 15-269.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation

Keywords - Domaini

TransmembraneImported

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000050013.
KOiK08884.
OMAiNGTATSC.
OrthoDBiEOG6B35XT.

Family and domain databases

Gene3Di3.40.30.10. 1 hit.
InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
PF13462. Thioredoxin_4. 1 hit.
[Graphical view]
SUPFAMiSSF52833. SSF52833. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0PST1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDATADSRE GSQFGPYRLR RIVGRGAMGD VYEAEDTVRE RVVALKLMSQ
60 70 80 90 100
TLSNDPVFRT RMQREARTAG RLQEPHVVPI HDYGEIDGQL YVDMRLIDGK
110 120 130 140 150
DLAAMLKRYG PLPPPRAVAI TRQIGSALDA AHAAGVTHRD VKPENILVSH
160 170 180 190 200
DDFAYLVDFG IASATSDEKL TQLGSTVGTL YYMAPERFSS GDVTYRADIY
210 220 230 240 250
ALACVLYECL TGSPPYRGDQ LSVIGAHLSQ PIPRPSAARP GIPAGFDNVI
260 270 280 290 300
ARGMAKDPAD RYATCGDLSA AAYSALATPD QDRATDILQR SQVAQLPAGF
310 320 330 340 350
ASTSPGGFAP SSPAVPVPGS APSTGWPAPS VPGAPVAPSA PVPTPWAGVP
360 370 380 390 400
GWGVGHTGTT GAPPWGQPPP EPTVAAKTWP WIAAAVAVVV VIAGVLGVVI
410 420 430 440 450
AHPWRSPGPP TASAPPPPPP DAVQLRVLND GVFIGSSAAT TTIDIFNEPI
460 470 480 490 500
CPPCGAFIRS YASDIDAAVA NKKLAVRYHL LNFLDEQSHT KTYSTRAVAA
510 520 530 540 550
SYCVAAQDDP KVYTDFYAAL FASDFQPQEA AASDRTDAEL AHLAQTVGAN
560 570 580
GTATSCIKAG NDMGTARTKA AAADATLSEL NAGLRRC
Length:587
Mass (Da):61,601
Last modified:January 9, 2007 - v1
Checksum:i347F0692A60C8564
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000325 Genomic DNA. Translation: ABL05400.1.
RefSeqiWP_011741011.1. NC_008611.1.
YP_906871.1. NC_008611.1.

Genome annotation databases

EnsemblBacteriaiABL05400; ABL05400; MUL_3180.
GeneIDi4553892.
KEGGimul:MUL_3180.
PATRICi18173744. VBIMycUlc37413_3705.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000325 Genomic DNA. Translation: ABL05400.1.
RefSeqiWP_011741011.1. NC_008611.1.
YP_906871.1. NC_008611.1.

3D structure databases

ProteinModelPortaliA0PST1.
SMRiA0PST1. Positions 15-269.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABL05400; ABL05400; MUL_3180.
GeneIDi4553892.
KEGGimul:MUL_3180.
PATRICi18173744. VBIMycUlc37413_3705.

Organism-specific databases

GenoListiMUL_3180.

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000050013.
KOiK08884.
OMAiNGTATSC.
OrthoDBiEOG6B35XT.

Family and domain databases

Gene3Di3.40.30.10. 1 hit.
InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
PF13462. Thioredoxin_4. 1 hit.
[Graphical view]
SUPFAMiSSF52833. SSF52833. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer."
    Stinear T.P., Seemann T., Pidot S., Frigui W., Reysset G., Garnier T., Meurice G., Simon D., Bouchier C., Ma L., Tichit M., Porter J.L., Ryan J., Johnson P.D.R., Davies J.K., Jenkin G.A., Small P.L.C., Jones L.M.
    , Tekaia F., Laval F., Daffe M., Parkhill J., Cole S.T.
    Genome Res. 17:192-200(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Agy99Imported.

Entry informationi

Entry nameiA0PST1_MYCUA
AccessioniPrimary (citable) accession number: A0PST1
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: June 24, 2015
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.