A0PRI7 (A0PRI7_MYCUA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Phosphoribosylaminoimidazole carboxylase ATPase subunit PurK (Air carboxylase) (AirC) EMBL ABL04956.1

Gene names

Name:	purK EMBL ABL04956.1
Ordered Locus Names:	MUL_2628

Organism

Mycobacterium ulcerans (strain Agy99) [Complete proteome] [HAMAP]

Taxonomic identifier

362242 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	424 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities

Contains 1 ATP-grasp domain. SAAS SAAS003135

Ontologies

Keywords
Biological process	Purine biosynthesis SAAS SAAS003135
Ligand	ATP-binding SAAS SAAS003135 Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	'de novo' IMP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ligase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro phosphoribosylaminoimidazole carboxylase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0PRI7 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: C8D9415CD8473C34	FASTA	424	45,425
	10 20 30 40 50 60 MIHNDLVLQP PNTPVMGHDT MMAVPSSRTP QVAMVGGGQL ARMTHQAAIA LGQNLRVLVN 70 80 90 100 110 120 SADDPAAQVT PNVVIGSHTD LDDLRRIAAG ADVVTFDHEH VPAELLDKLV AEGVVLAPPP 130 140 150 160 170 180 QALVHAQDKL VMRRRLQALD VPVPRYLGIH QLEELGELDA FARQLDAPLV VKAVRGGYDG 190 200 210 220 230 240 RGVQMARDLA DARDIASGYL AGGVPVLVEE RVQLRRELSA LVARSPFGQG AAWPVVETVQ 250 260 270 280 290 300 QDGICVAVIA PAPALSAQAG ADAQQLALRL AAELGVVGVL AVELFETTDG ALVVNELAMR 310 320 330 340 350 360 PHNSGHWTMD GSRTSQFEQH LRAVLDYPLG DTEAIAPVTV MTNVLGAAAQ PAMSLDERLH 370 380 390 400 410 420 HLFARMPDAR VHLYGKDERP GRKVGHINFL GFDPAAVAGL RERAELAAHW LSHGQWTDGW DPHG

References

[1]

"Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer." Stinear T.P., Seemann T., Pidot S., Frigui W., Reysset G., Garnier T., Meurice G., Simon D., Bouchier C., Ma L., Tichit M., Porter J.L., Ryan J., Johnson P.D.R., Davies J.K., Jenkin G.A., Small P.L.C., Jones L.M. , Tekaia F., Laval F., Daffe M., Parkhill J., Cole S.T. Genome Res. 17:192-200(2007) [PubMed: 17210928] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000325 Genomic DNA. Translation: ABL04956.1.
RefSeq	YP_906427.1. NC_008611.1.
3D structure databases
ProteinModelPortal	A0PRI7.
ModBase	Search...
Protein-protein interaction databases
STRING	A0PRI7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000073790; EBMYCP00000071795; EBMYCG00000073785.
GeneID	4549865.
GenomeReviews	Gene locus MUL_2628 in contig CP000325_GR.
KEGG	mul:MUL_2628.
PATRIC	18172478. VBIMycUlc37413_3078.
Organism-specific databases
GenoList	MUL_2628.
CMR	Search...
Phylogenomic databases
eggNOG	COG0026.
GeneTree	EBGT00050000015722.
HOGENOM	HBG516369.
OMA	GRKMGHF.
PhylomeDB	A0PRI7.
ProtClustDB	PRK06019.
Family and domain databases
InterPro	IPR005875. AIR_COase_ATPase-su. IPR011761. ATP-grasp. IPR003135. ATP-grasp_carboxylate-amine. IPR013815. ATP_grasp_subdomain_1. IPR013816. ATP_grasp_subdomain_2. IPR013817. Pre-ATP_grasp. IPR016185. PreATP-grasp-like. IPR011054. Rudment_hybrid_motif. [Graphical view]
Gene3D	G3DSA:3.30.1490.20. ATP_grasp_subdomain_1. 1 hit. G3DSA:3.30.470.20. ATP_grasp_subdomain_2. 1 hit. G3DSA:3.40.50.20. Pre-ATP_grasp. 1 hit.
KO	K01589.
Pfam	PF02222. ATP-grasp. 1 hit. [Graphical view]
SUPFAM	SSF52440. PreATP-grasp-like. 1 hit. SSF51246. Rudmnt_hyb_motif. 1 hit.
TIGRFAMs	TIGR01161. PurK. 1 hit.
PROSITE	PS50975. ATP_GRASP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A0PRI7_MYCUA

Accession

Primary (citable) accession number: A0PRI7

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)