A0PQ48 (A0PQ48_MYCUA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Ribonuclease III Rnc EMBL ABL04467.1

Gene names

Name:	rnc EMBL ABL04467.1
Ordered Locus Names:	MUL_2030

Organism

Mycobacterium ulcerans (strain Agy99) [Complete proteome] [HAMAP]

Taxonomic identifier

362242 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	243 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs By similarity. SAAS SAAS011907
Catalytic activity	Endonucleolytic cleavage to 5'-phosphomonoester. SAAS SAAS011907
Subcellular location	Cytoplasm By similarity SAAS SAAS011907.
Sequence similarities	Contains 1 DRBM (double-stranded RNA-binding) domain. SAAS SAAS011907 Contains 1 RNase III domain. SAAS SAAS011907

Ontologies

Keywords
Cellular component	Cytoplasm SAAS SAAS011907
Ligand	RNA-binding SAAS SAAS011907
Molecular function	Endonuclease SAAS SAAS011907 Hydrolase Nuclease
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	RNA processing Inferred from electronic annotation. Source: InterPro rRNA catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	double-stranded RNA binding Inferred from electronic annotation. Source: InterPro ribonuclease III activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0PQ48 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: F0BFD39B26BB94CA	FASTA	243	25,562
	10 20 30 40 50 60 MSVSRQALLD AVGVELPEEL VTLALTHRSY AYENGGLPTN ERLEFLGDAV LGLTITDELF 70 80 90 100 110 120 HRHPERSEGD LAKLRASVVN TQALADVARH LSDHGLGAHM LLGRGEANTG GADKSSILAD 130 140 150 160 170 180 GMESLLGAIY LHHGMEVARE AILRIFGPLL DAAPTLGAGL DWKTSLQELT ASRSLGAPSY 190 200 210 220 230 240 AVTSTGPDHH KEFTAVVVVN NTEYGSGVGR SKKEAEQKAA AAAYQALEGL EVLDGAMPGN SSA

References

[1]

"Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer." Stinear T.P., Seemann T., Pidot S., Frigui W., Reysset G., Garnier T., Meurice G., Simon D., Bouchier C., Ma L., Tichit M., Porter J.L., Ryan J., Johnson P.D.R., Davies J.K., Jenkin G.A., Small P.L.C., Jones L.M. , Tekaia F., Laval F., Daffe M., Parkhill J., Cole S.T. Genome Res. 17:192-200(2007) [PubMed: 17210928] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000325 Genomic DNA. Translation: ABL04467.1.
RefSeq	YP_905938.1. NC_008611.1.
3D structure databases
ProteinModelPortal	A0PQ48.
SMR	A0PQ48. Positions 4-155.
ModBase	Search...
Protein-protein interaction databases
STRING	A0PQ48.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000074051; EBMYCP00000072056; EBMYCG00000074046.
GeneID	4551081.
GenomeReviews	Gene locus MUL_2030 in contig CP000325_GR.
KEGG	mul:MUL_2030.
PATRIC	18171117. VBIMycUlc37413_2406.
Organism-specific databases
GenoList	MUL_2030.
CMR	Search...
Phylogenomic databases
eggNOG	COG0571.
GeneTree	EBGT00050000017732.
HOGENOM	HBG744556.
OMA	ALTHKSF.
PhylomeDB	A0PQ48.
ProtClustDB	PRK00102.
Family and domain databases
HAMAP	MF_00104. RNase_III. [Tree]
InterPro	IPR001159. Ds-RNA-bd. IPR014720. dsRNA-bd-like. IPR000999. RNase_III. IPR011907. RNase_III_bac. [Graphical view]
Gene3D	G3DSA:3.30.160.20. dsRNA-bd-like. 1 hit. G3DSA:1.10.1520.10. RNase_III. 1 hit.
KO	K03685.
PANTHER	PTHR11207. PTHR11207. 1 hit.
Pfam	PF00035. dsrm. 1 hit. PF00636. Ribonuclease_3. 1 hit. [Graphical view]
SMART	SM00358. DSRM. 1 hit. SM00535. RIBOc. 1 hit. [Graphical view]
SUPFAM	SSF69065. RNase_III. 1 hit.
TIGRFAMs	TIGR02191. RNaseIII. 1 hit.
PROSITE	PS50137. DS_RBD. 1 hit. PS00517. RNASE_3_1. 1 hit. PS50142. RNASE_3_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A0PQ48_MYCUA

Accession

Primary (citable) accession number: A0PQ48

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)