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A0PPN8

- CAPP_MYCUA

UniProt

A0PPN8 - CAPP_MYCUA

Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Mycobacterium ulcerans (strain Agy99)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (09 Jan 2007)
      Previous versions | rss
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    Functioni

    Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

    Cofactori

    Magnesium.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei161 – 1611UniRule annotation
    Active sitei593 – 5931UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    Lyase

    Keywords - Biological processi

    Carbon dioxide fixation

    Keywords - Ligandi

    Magnesium

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:ppcUniRule annotation
    Ordered Locus Names:MUL_1836
    OrganismiMycobacterium ulcerans (strain Agy99)
    Taxonomic identifieri362242 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
    ProteomesiUP000000765: Chromosome

    Organism-specific databases

    GenoListiMUL_1836.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 935935Phosphoenolpyruvate carboxylasePRO_1000025567Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi362242.MUL_1836.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 1 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2352.
    HOGENOMiHOG000238647.
    KOiK01595.
    OMAiELSTISC.
    OrthoDBiEOG6TJ7T8.

    Family and domain databases

    HAMAPiMF_00595. PEPcase_type1.
    InterProiIPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF00311. PEPcase. 1 hit.
    [Graphical view]
    PRINTSiPR00150. PEPCARBXLASE.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    PROSITEiPS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A0PPN8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVEVSDTALE PIGDVHRTRI GREATEPMRA DIRLLGAILG DTVREQNGDE    50
    VFELVERARV EAFRVRHSEI DRAEMARMFE GIDIHHAIPI IRAFSHFALL 100
    ANVAEDIHRE RRRSIHVAAG EPPRDSSLTA TYMKLYAAQL DSATIAEALK 150
    GALVSPVITA HPTETRRRTI FETQHRITQL MRLHAEGHTE TDDGRGIEVE 200
    LRRQVLRLWQ TALIRLFRLQ ISDEIEVGLR YYPAALFEVI SQVNAEVRDA 250
    LRARWPDADL LSEPILRPGS WIGGDRDGNP NVTAEVVRLA TGSAAFTALA 300
    HYLAELTALA QELSMSARLI TVTPELATLA DACPAGARPD EPYRRALQVV 350
    RGRLSATAAE ILDQQPQHTL ELGLPPYATA AELRADLDTI DASLHNHGAG 400
    LLADDRLARL REAVRVFGFH LSGLDMRQNS DVHEQVVGEL LAWAGVHPDY 450
    TSLAEAERVE LLAAELSTRR PLIRDGAQLS DLARSELGVL AAAAHAVWTF 500
    GPAAVPNYII SMCWSVSDML EAAVLLKEVG LLDASESEPY CPVGISPLFE 550
    TIEDLHNGAA ILQAMLDLPL YRALVTARGG CQEVMLGYSD SNKDGGYLAA 600
    NWAVYRAELA LVETARKTGI RLRLFHGRGG TVGRGGGPSY QAILAQPPGA 650
    VSGSLRLTEQ GEVIAAKYAE PQMARRNLES LLAATLESTL LAVEGLGDTA 700
    APAYAVLDEV AALAQRAYAE LVHETPGFVE YFKASTPVSE FGALNIGSRP 750
    TSRKPTASIA DLRAIPWVLA WSQSRVMLPG WYGTGSAFEQ WLAAGPESEA 800
    DRLQVLHDLY QRWPFFRSVL SNMAQVMAKS DLELAARYSE LVADETLRRR 850
    VFDKIADEHH RTIAMYKRIT GQDDLLADNP ALARSVFNRF PYLEPLNHLQ 900
    VELLRRYRSG EDDESVQRGI LLTMNGLASA LRNSG 935
    Length:935
    Mass (Da):102,784
    Last modified:January 9, 2007 - v1
    Checksum:i4A790C15C4CFB92D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000325 Genomic DNA. Translation: ABL04307.1.
    RefSeqiYP_905778.1. NC_008611.1.

    Genome annotation databases

    EnsemblBacteriaiABL04307; ABL04307; MUL_1836.
    GeneIDi4551687.
    KEGGimul:MUL_1836.
    PATRICi18170688. VBIMycUlc37413_2195.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000325 Genomic DNA. Translation: ABL04307.1 .
    RefSeqi YP_905778.1. NC_008611.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 362242.MUL_1836.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABL04307 ; ABL04307 ; MUL_1836 .
    GeneIDi 4551687.
    KEGGi mul:MUL_1836.
    PATRICi 18170688. VBIMycUlc37413_2195.

    Organism-specific databases

    GenoListi MUL_1836.

    Phylogenomic databases

    eggNOGi COG2352.
    HOGENOMi HOG000238647.
    KOi K01595.
    OMAi ELSTISC.
    OrthoDBi EOG6TJ7T8.

    Family and domain databases

    HAMAPi MF_00595. PEPcase_type1.
    InterProi IPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF00311. PEPcase. 1 hit.
    [Graphical view ]
    PRINTSi PR00150. PEPCARBXLASE.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    PROSITEi PS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer."
      Stinear T.P., Seemann T., Pidot S., Frigui W., Reysset G., Garnier T., Meurice G., Simon D., Bouchier C., Ma L., Tichit M., Porter J.L., Ryan J., Johnson P.D.R., Davies J.K., Jenkin G.A., Small P.L.C., Jones L.M.
      , Tekaia F., Laval F., Daffe M., Parkhill J., Cole S.T.
      Genome Res. 17:192-200(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Agy99.

    Entry informationi

    Entry nameiCAPP_MYCUA
    AccessioniPrimary (citable) accession number: A0PPN8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: January 9, 2007
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3