A0PPJ5 (A0PPJ5_MYCUA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Guanylate kinase Gmk EMBL ABL04264.1

Gene names

Name:	gmk EMBL ABL04264.1
Ordered Locus Names:	MUL_1788

Organism

Mycobacterium ulcerans (strain Agy99) [Complete proteome] [HAMAP]

Taxonomic identifier

362242 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	208 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Essential for recycling GMP and indirectly, cGMP By similarity. SAAS SAAS020590
Catalytic activity	ATP + GMP = ADP + GDP. SAAS SAAS020590
Subcellular location	Cytoplasm By similarity SAAS SAAS020590.
Sequence similarities	Contains 1 guanylate kinase-like domain. SAAS SAAS017665

Ontologies

Keywords
Cellular component	Cytoplasm SAAS SAAS020590
Ligand	ATP-binding SAAS SAAS020590 Nucleotide-binding
Molecular function	Kinase SAAS SAAS020590 EMBL ABL04264.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	purine nucleotide metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW guanylate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0PPJ5 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 8B9A01BF0A7E9B72	FASTA	208	21,789
	10 20 30 40 50 60 MPGGGADSGA PMSAGGGPGT GHVVVLSGPS AVGKSTVVRC LRERIPNLHF SVSATTRAPR 70 80 90 100 110 120 PGEVDGVDYH FVTPESFQQM IDQGELLEWA EIHGGLHRSG TPAQPVREAT ASGVPVLIEV 130 140 150 160 170 180 DLAGGRAVKK AMPEAISVFL APPSWEDLKA RLVGRGTETP DVIRRRLQTA QTELAAQRDF 190 200 DKVVVNGRLE SACAELVSLL VRTVPGSG

References

[1]

"Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer." Stinear T.P., Seemann T., Pidot S., Frigui W., Reysset G., Garnier T., Meurice G., Simon D., Bouchier C., Ma L., Tichit M., Porter J.L., Ryan J., Johnson P.D.R., Davies J.K., Jenkin G.A., Small P.L.C., Jones L.M. , Tekaia F., Laval F., Daffe M., Parkhill J., Cole S.T. Genome Res. 17:192-200(2007) [PubMed: 17210928] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000325 Genomic DNA. Translation: ABL04264.1.
RefSeq	YP_905735.1. NC_008611.1.
3D structure databases
ProteinModelPortal	A0PPJ5.
SMR	A0PPJ5. Positions 21-201.
ModBase	Search...
Protein-protein interaction databases
STRING	A0PPJ5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000076898; EBMYCP00000074903; EBMYCG00000076893.
GeneID	4551712.
GenomeReviews	Gene locus MUL_1788 in contig CP000325_GR.
KEGG	mul:MUL_1788.
PATRIC	18170577. VBIMycUlc37413_2140.
Organism-specific databases
GenoList	MUL_1788.
CMR	Search...
Phylogenomic databases
eggNOG	COG0194.
GeneTree	EBGT00050000017746.
HOGENOM	HBG671982.
OMA	EWAEFAG.
PhylomeDB	A0PPJ5.
ProtClustDB	PRK00300.
Family and domain databases
HAMAP	MF_00328. Guanylate_kinase. [Tree]
InterPro	IPR008144. Guanylate_kin. IPR008145. Guanylate_kin/L-typ_Ca_channel. IPR020590. Guanylate_kinase_CS. IPR017665. Guanylate_kinase_sub. [Graphical view]
KO	K00942.
Pfam	PF00625. Guanylate_kin. 1 hit. [Graphical view]
SMART	SM00072. GuKc. 1 hit. [Graphical view]
TIGRFAMs	TIGR03263. Guanyl_kin. 1 hit.
PROSITE	PS00856. GUANYLATE_KINASE_1. 1 hit. PS50052. GUANYLATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A0PPJ5_MYCUA

Accession

Primary (citable) accession number: A0PPJ5

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	December 14, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)