A0PM77 (A0PM77_MYCUA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
50S ribosomal protein L5 HAMAP MF_01333 RuleBase RU003931

Gene names

Name:	rplE HAMAP MF_01333 EMBL ABL03446.1
Ordered Locus Names:	MUL_0806

Organism

Mycobacterium ulcerans (strain Agy99) [Complete proteome] [HAMAP]

Taxonomic identifier

362242 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	190 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement By similarity. RuleBase RU003931 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs By similarity. HAMAP MF_01333
Subunit structure	Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome By similarity. HAMAP MF_01333
Sequence similarities	Belongs to the ribosomal protein L5P family. HAMAP MF_01333 RuleBase RU003930

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding HAMAP MF_01333 RuleBase RU003931 tRNA-binding HAMAP MF_01333 RuleBase RU003931
Molecular function	Ribonucleoprotein Ribosomal protein HAMAP MF_01333 RuleBase RU003930 EMBL ABL03446.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: HAMAP
Cellular component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	rRNA binding Inferred from electronic annotation. Source: HAMAP structural constituent of ribosome Inferred from electronic annotation. Source: InterPro tRNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0PM77 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 378F50C9C64B04E4	FASTA	190	21,315
	10 20 30 40 50 60 MSTTDSAVKI PPRLKERYRS EIRDVLHKQF GYGNVMQIPT VTKVVVNMGV GEAARDAKLI 70 80 90 100 110 120 NGAVSDLALI TGQRPEIRKA RKSIAQFKLR EGMPVGVRAT LRGDRMWEFL DRLTSIALPR 130 140 150 160 170 180 IRDFRGLSPK QFDGVGNYTF GLAEQPVFHE IDVDKIDRVR GMDINVVTSA TTDEEGRALL 190 RALGFPFKEN

References

[1]

"Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer." Stinear T.P., Seemann T., Pidot S., Frigui W., Reysset G., Garnier T., Meurice G., Simon D., Bouchier C., Ma L., Tichit M., Porter J.L., Ryan J., Johnson P.D.R., Davies J.K., Jenkin G.A., Small P.L.C., Jones L.M. , Tekaia F., Laval F., Daffe M., Parkhill J., Cole S.T. Genome Res. 17:192-200(2007) [PubMed: 17210928] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000325 Genomic DNA. Translation: ABL03446.1.
RefSeq	YP_904917.1. NC_008611.1.
3D structure databases
ProteinModelPortal	A0PM77.
SMR	A0PM77. Positions 11-189.
ModBase	Search...
Protein-protein interaction databases
STRING	A0PM77.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000075754; EBMYCP00000073759; EBMYCG00000075749.
GeneID	4551343.
GenomeReviews	Gene locus MUL_0806 in contig CP000325_GR.
KEGG	mul:MUL_0806.
PATRIC	18168300. VBIMycUlc37413_1012.
Organism-specific databases
GenoList	MUL_0806.
CMR	Search...
Phylogenomic databases
eggNOG	COG0094.
GeneTree	EBGT00050000016450.
HOGENOM	HBG592167.
OMA	RQGMPIG.
PhylomeDB	A0PM77.
ProtClustDB	PRK00010.
Family and domain databases
HAMAP	MF_01333_B. Ribosomal_L5_B. [Tree]
InterPro	IPR002132. Ribosomal_L5. IPR020930. Ribosomal_L5_bac-type. IPR022803. Ribosomal_L5_domain. [Graphical view]
Gene3D	G3DSA:3.30.1440.10. Ribosomal_L5. 1 hit.
KO	K02931.
PANTHER	PTHR11994. Ribosomal_L5. 1 hit.
Pfam	PF00281. Ribosomal_L5. 1 hit. PF00673. Ribosomal_L5_C. 1 hit. [Graphical view]
PIRSF	PIRSF002161. Ribosomal_L5. 1 hit.
SUPFAM	SSF55282. Ribosomal_L5. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A0PM77_MYCUA

Accession

Primary (citable) accession number: A0PM77

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)