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Protein
Submitted name:

Cystathionine gamma-synthase MetB (Cgs)

Gene

metB

Organism
Mycobacterium ulcerans (strain Agy99)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BRENDAi2.5.1.48. 8016.

Names & Taxonomyi

Protein namesi
Submitted name:
Cystathionine gamma-synthase MetB (Cgs)Imported
Gene namesi
Name:metBImported
Ordered Locus Names:MUL_0201Imported
OrganismiMycobacterium ulcerans (strain Agy99)Imported
Taxonomic identifieri362242 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000000765 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei208N6-(pyridoxal phosphate)lysineUniRule annotation1

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3QHXX-ray1.65A/B/C/D1-388[»]
3QI6X-ray1.91A/B/C/D1-388[»]
ProteinModelPortaliA0PKT3.
SMRiA0PKT3.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiA0PKT3.

Family & Domainsi

Sequence similaritiesi

Belongs to the trans-sulfuration enzymes family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000246415.
KOiK01739.
OMAiTHACIPK.
OrthoDBiPOG091H053G.

Family and domain databases

CDDicd00614. CGS_like. 1 hit.
Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR000277. Cys/Met-Metab_PyrdxlP-dep_enz.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11808. PTHR11808. 1 hit.
PfamiPF01053. Cys_Met_Meta_PP. 1 hit.
[Graphical view]
PIRSFiPIRSF001434. CGS. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00868. CYS_MET_METAB_PP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0PKT3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKDDHKAQHR FAGLATRAIH SGYRPDPATG AVNAPIYASS TFAQDGVGGL
60 70 80 90 100
RGGYEYARTG NPTRTALEAA LAAVEDAAFG RAFSSGMAAA DCALRAMLRP
110 120 130 140 150
GDHVVIPDDA YGGTFRLIDK VFTGWNVEYT PVALADLDAV RAAIRPTTRL
160 170 180 190 200
IWVETPTNPL LSIADIAGIA QLGADSSAKV LVDNTFASPA LQQPLSLGAD
210 220 230 240 250
VVLHSTTKYI GGHSDVVGGA LVTNDEELDQ SFAFLQNGAG AVPGPFDAYL
260 270 280 290 300
TMRGLKTLVL RMQRHSENAA AVAEFLAEHP AISTVLYPGL PSHPGHAVAA
310 320 330 340 350
RQMRGFGGMV SVRMRAGRTA AEQLCAKTNI FILAESLGSV ESLIEHPSAM
360 370 380
THASTAGSQL EVPDDLVRLS VGIEDVADLL DDLKQALG
Length:388
Mass (Da):40,723
Last modified:January 9, 2007 - v1
Checksum:iFEBDDD888F074207
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000325 Genomic DNA. Translation: ABL02952.1.

Genome annotation databases

EnsemblBacteriaiABL02952; ABL02952; MUL_0201.
KEGGimul:MUL_0201.
PATRICi18166877. VBIMycUlc37413_0317.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000325 Genomic DNA. Translation: ABL02952.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3QHXX-ray1.65A/B/C/D1-388[»]
3QI6X-ray1.91A/B/C/D1-388[»]
ProteinModelPortaliA0PKT3.
SMRiA0PKT3.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABL02952; ABL02952; MUL_0201.
KEGGimul:MUL_0201.
PATRICi18166877. VBIMycUlc37413_0317.

Phylogenomic databases

HOGENOMiHOG000246415.
KOiK01739.
OMAiTHACIPK.
OrthoDBiPOG091H053G.

Enzyme and pathway databases

BRENDAi2.5.1.48. 8016.

Miscellaneous databases

EvolutionaryTraceiA0PKT3.

Family and domain databases

CDDicd00614. CGS_like. 1 hit.
Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR000277. Cys/Met-Metab_PyrdxlP-dep_enz.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11808. PTHR11808. 1 hit.
PfamiPF01053. Cys_Met_Meta_PP. 1 hit.
[Graphical view]
PIRSFiPIRSF001434. CGS. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00868. CYS_MET_METAB_PP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA0PKT3_MYCUA
AccessioniPrimary (citable) accession number: A0PKT3
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: November 2, 2016
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.