A0PKN7 (A0PKN7_MYCUA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Glucose-6-phosphate 1-dehydrogenase RuleBase RU000497
EC=1.1.1.49 RuleBase RU000497

Gene names

Name:	zwf1 EMBL ABL02906.1
Ordered Locus Names:	MUL_0149

Organism

Mycobacterium ulcerans (strain Agy99) [Complete proteome] [HAMAP]

Taxonomic identifier

362242 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	338 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH. RuleBase RU000497
Pathway	Carbohydrate degradation; pentose phosphate pathway. RuleBase RU000497
Sequence similarities	Belongs to the glucose-6-phosphate dehydrogenase family. RuleBase RU000497

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glucose metabolism RuleBase RU000497
Ligand	NADP RuleBase RU000497
Molecular function	Oxidoreductase RuleBase RU000497
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucose metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro glucose-6-phosphate dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0PKN7 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 10527352ECF4E6C9	FASTA	338	38,369
	10 20 30 40 50 60 MLRCARVAVE KPFGHDLDSA RELNSRLRAV LNEDQILRVD HFLGKQPVVE LQYLRFANRD 70 80 90 100 110 120 LAELWDRKSV SEIHVTMAEN FGVEDRGKFY DAVGALRDVV QNHLLQVLAL VAMEPPVGPG 130 140 150 160 170 180 ADDLNDKKAE VFRAMPALQT AHYVRGQYQG YGDVPGVAKD SQTETYVALR TEIDNWRWAG 190 200 210 220 230 240 VPVFLRAGKA LPERVTEVRM FLHHVPGLAF LPNRRPAEPN QIVLRIDPDP GMRLQISAQT 250 260 270 280 290 300 GDSWQGVHLD SSFAEDLGEP IRPYERLLYA GLIGDRQLFA REDAIEQTWR IVQPVLDDPG 310 320 330 EIHPYDRGSW GPEAAQTLLR GHRNWQQPWL PRSAEARQ

References

[1]

"Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer." Stinear T.P., Seemann T., Pidot S., Frigui W., Reysset G., Garnier T., Meurice G., Simon D., Bouchier C., Ma L., Tichit M., Porter J.L., Ryan J., Johnson P.D.R., Davies J.K., Jenkin G.A., Small P.L.C., Jones L.M. , Tekaia F., Laval F., Daffe M., Parkhill J., Cole S.T. Genome Res. 17:192-200(2007) [PubMed: 17210928] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000325 Genomic DNA. Translation: ABL02906.1.
RefSeq	YP_904377.1. NC_008611.1.
3D structure databases
ProteinModelPortal	A0PKN7.
ModBase	Search...
Protein-protein interaction databases
STRING	A0PKN7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000074447; EBMYCP00000072452; EBMYCG00000074442.
GeneID	4552872.
GenomeReviews	Gene locus MUL_0149 in contig CP000325_GR.
KEGG	mul:MUL_0149.
PATRIC	18166761. VBIMycUlc37413_0260.
Organism-specific databases
GenoList	MUL_0149.
CMR	Search...
Phylogenomic databases
eggNOG	COG0364.
GeneTree	EBGT00050000015853.
HOGENOM	HBG322449.
OMA	WSESIDD.
ProtClustDB	PRK12853.
Family and domain databases
InterPro	IPR001282. G6P_DH. IPR019796. G6P_DH_AS. IPR022675. G6P_DH_C. IPR022674. G6P_DH_NAD-bd. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00036.
PANTHER	PTHR23429. G6PDH. 1 hit.
Pfam	PF02781. G6PD_C. 1 hit. PF00479. G6PD_N. 1 hit. [Graphical view]
PRINTS	PR00079. G6PDHDRGNASE.
TIGRFAMs	TIGR00871. Zwf. 1 hit.
PROSITE	PS00069. G6P_DEHYDROGENASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A0PKN7_MYCUA

Accession

Primary (citable) accession number: A0PKN7

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)