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A0PJN4 (U2QL1_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ubiquitin-conjugating enzyme E2Q-like protein 1

EC=6.3.2.19
Gene names
Name:Ube2ql1
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length161 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Catalyzes the covalent attachment of ubiquitin to other proteins Potential.

Catalytic activity

ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.

Pathway

Protein modification; protein ubiquitination.

Sequence similarities

Belongs to the ubiquitin-conjugating enzyme family.

Sequence caution

The sequence AAI16980.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

The sequence AAI16982.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Ontologies

Keywords
   Biological processUbl conjugation pathway
   LigandATP-binding
Nucleotide-binding
   Molecular functionLigase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

ubiquitin-protein transferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 161161Ubiquitin-conjugating enzyme E2Q-like protein 1
PRO_0000335812

Sites

Active site881Glycyl thioester intermediate By similarity

Experimental info

Sequence conflict331Q → P in AAH58543. Ref.1

Sequences

Sequence LengthMass (Da)Tools
A0PJN4 [UniParc].

Last modified May 20, 2008. Version 2.
Checksum: A7DC159CFA09DA00

FASTA16118,364
        10         20         30         40         50         60 
MKELQDIARL SDRFISVELV NENLFDWNVK LHQVDKDSVL WQDMKETNTE FILLNLTFPD 

        70         80         90        100        110        120 
NFPFSPPFMR VLSPRLENGY VLDGGAICME LLTPRGWSSA YTVEAVMRQF AASLVKGQGR 

       130        140        150        160 
ICRKAGKSKK SFSRKEAEAT FKSLVKTHEK YGWVTPPVSD G 

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6.
Tissue: Brain.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC058543 mRNA. Translation: AAH58543.1.
BC116979 mRNA. Translation: AAI16980.1. Different initiation.
BC116981 mRNA. Translation: AAI16982.1. Different initiation.
RefSeqNP_001138634.1. NM_001145162.1.
UniGeneMm.23960.

3D structure databases

ProteinModelPortalA0PJN4.
SMRA0PJN4. Positions 1-148.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteA0PJN4.

Proteomic databases

PRIDEA0PJN4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID76980.
KEGGmmu:76980.

Organism-specific databases

CTD134111.
MGIMGI:1924230. Ube2ql1.

Phylogenomic databases

eggNOGNOG272407.
HOGENOMHOG000007757.
HOVERGENHBG061368.
InParanoidA0PJN4.
KOK10582.
PhylomeDBA0PJN4.

Enzyme and pathway databases

UniPathwayUPA00143.

Gene expression databases

ArrayExpressA0PJN4.
BgeeA0PJN4.
GenevestigatorA0PJN4.

Family and domain databases

Gene3D3.10.110.10. 1 hit.
InterProIPR000608. UBQ-conjugat_E2.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view]
PfamPF00179. UQ_con. 1 hit.
[Graphical view]
SUPFAMSSF54495. SSF54495. 1 hit.
PROSITEPS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio346228.
PROA0PJN4.
SOURCESearch...

Entry information

Entry nameU2QL1_MOUSE
AccessionPrimary (citable) accession number: A0PJN4
Secondary accession number(s): Q6PDR7
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 20, 2008
Last modified: April 16, 2014
This is version 58 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot