Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A0PJN4

- U2QL1_MOUSE

UniProt

A0PJN4 - U2QL1_MOUSE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Ubiquitin-conjugating enzyme E2Q-like protein 1

Gene

Ube2ql1

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Catalyzes the covalent attachment of ubiquitin to other proteins.PROSITE-ProRule annotation

Catalytic activityi

ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.PROSITE-ProRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei88 – 881Glycyl thioester intermediatePROSITE-ProRule annotation

GO - Molecular functioni

  1. acid-amino acid ligase activity Source: InterPro
  2. ATP binding Source: UniProtKB-KW

GO - Biological processi

  1. protein ubiquitination Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Ubl conjugation pathway

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00143.

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquitin-conjugating enzyme E2Q-like protein 1 (EC:6.3.2.19)
Gene namesi
Name:Ube2ql1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Unplaced

Organism-specific databases

MGIiMGI:1924230. Ube2ql1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 161161Ubiquitin-conjugating enzyme E2Q-like protein 1PRO_0000335812Add
BLAST

Proteomic databases

PRIDEiA0PJN4.

PTM databases

PhosphoSiteiA0PJN4.

Expressioni

Gene expression databases

BgeeiA0PJN4.
ExpressionAtlasiA0PJN4. baseline.
GenevestigatoriA0PJN4.

Structurei

3D structure databases

ProteinModelPortaliA0PJN4.
SMRiA0PJN4. Positions 1-148.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ubiquitin-conjugating enzyme family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiNOG272407.
HOGENOMiHOG000007757.
HOVERGENiHBG061368.
InParanoidiA0PJN4.
KOiK10582.
PhylomeDBiA0PJN4.

Family and domain databases

Gene3Di3.10.110.10. 1 hit.
InterProiIPR000608. UBQ-conjugat_E2.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view]
PfamiPF00179. UQ_con. 1 hit.
[Graphical view]
SUPFAMiSSF54495. SSF54495. 1 hit.
PROSITEiPS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0PJN4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKELQDIARL SDRFISVELV NENLFDWNVK LHQVDKDSVL WQDMKETNTE
60 70 80 90 100
FILLNLTFPD NFPFSPPFMR VLSPRLENGY VLDGGAICME LLTPRGWSSA
110 120 130 140 150
YTVEAVMRQF AASLVKGQGR ICRKAGKSKK SFSRKEAEAT FKSLVKTHEK
160
YGWVTPPVSD G
Length:161
Mass (Da):18,364
Last modified:May 20, 2008 - v2
Checksum:iA7DC159CFA09DA00
GO

Sequence cautioni

The sequence AAI16980.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
The sequence AAI16982.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti33 – 331Q → P in AAH58543. (PubMed:15489334)Curated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC058543 mRNA. Translation: AAH58543.1.
BC116979 mRNA. Translation: AAI16980.1. Different initiation.
BC116981 mRNA. Translation: AAI16982.1. Different initiation.
RefSeqiNP_001138634.1. NM_001145162.1.
UniGeneiMm.23960.

Genome annotation databases

GeneIDi76980.
KEGGimmu:76980.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC058543 mRNA. Translation: AAH58543.1 .
BC116979 mRNA. Translation: AAI16980.1 . Different initiation.
BC116981 mRNA. Translation: AAI16982.1 . Different initiation.
RefSeqi NP_001138634.1. NM_001145162.1.
UniGenei Mm.23960.

3D structure databases

ProteinModelPortali A0PJN4.
SMRi A0PJN4. Positions 1-148.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei A0PJN4.

Proteomic databases

PRIDEi A0PJN4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 76980.
KEGGi mmu:76980.

Organism-specific databases

CTDi 134111.
MGIi MGI:1924230. Ube2ql1.

Phylogenomic databases

eggNOGi NOG272407.
HOGENOMi HOG000007757.
HOVERGENi HBG061368.
InParanoidi A0PJN4.
KOi K10582.
PhylomeDBi A0PJN4.

Enzyme and pathway databases

UniPathwayi UPA00143 .

Miscellaneous databases

NextBioi 346228.
PROi A0PJN4.
SOURCEi Search...

Gene expression databases

Bgeei A0PJN4.
ExpressionAtlasi A0PJN4. baseline.
Genevestigatori A0PJN4.

Family and domain databases

Gene3Di 3.10.110.10. 1 hit.
InterProi IPR000608. UBQ-conjugat_E2.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view ]
Pfami PF00179. UQ_con. 1 hit.
[Graphical view ]
SUPFAMi SSF54495. SSF54495. 1 hit.
PROSITEi PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6.
    Tissue: Brain.

Entry informationi

Entry nameiU2QL1_MOUSE
AccessioniPrimary (citable) accession number: A0PJN4
Secondary accession number(s): Q6PDR7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 20, 2008
Last modified: October 29, 2014
This is version 61 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3