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Protein
Submitted name:

SCRIB protein

Gene

SCRIB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
SCRIB proteinImported
Gene namesi
Name:SCRIBImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134936275.

PTM / Processingi

Proteomic databases

PaxDbiA0PJK8.
PeptideAtlasiA0PJK8.
PRIDEiA0PJK8.

Expressioni

Gene expression databases

GenevisibleiA0PJK8. HS.

Interactioni

Protein-protein interaction databases

IntActiA0PJK8. 1 interaction.
STRINGi9606.ENSP00000349486.

Structurei

3D structure databases

ProteinModelPortaliA0PJK8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini24 – 11188PDZ (DHR)InterPro annotationAdd
BLAST
Domaini158 – 24689PDZ (DHR)InterPro annotationAdd
BLAST
Domaini300 – 38990PDZ (DHR)InterPro annotationAdd
BLAST
Domaini396 – 48489PDZ (DHR)InterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 4 PDZ (DHR) domains.UniRule annotation

Phylogenomic databases

eggNOGiENOG410KCZ0. Eukaryota.
COG4886. LUCA.
HOGENOMiHOG000113281.

Family and domain databases

Gene3Di2.30.42.10. 4 hits.
InterProiIPR001478. PDZ.
[Graphical view]
PfamiPF00595. PDZ. 4 hits.
[Graphical view]
SMARTiSM00228. PDZ. 4 hits.
[Graphical view]
SUPFAMiSSF50156. SSF50156. 4 hits.
PROSITEiPS50106. PDZ. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

A0PJK8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
KGVSFDQANN LLIEPARIEE EELTLTILRQ TGGLGISIAG GKGSTPYKGD
60 70 80 90 100
DEGIFISRVS EEGPAARAGV RVGDKLLEVN GVALQGAEHH EAVEALRGAG
110 120 130 140 150
TAVQMRVWRE RMVEPENAVT ITPLRPEDDY SPRERRGGGL RLPLLPPESP
160 170 180 190 200
GPLRQRHVAC LARSERGLGF SIAGGKGSTP YRAGDAGIFV SRIAEGGAAH
210 220 230 240 250
RAGTLQVGDR VLSINGVDVT EARHDHAVSL LTAASPTIAL LLEREAGGPL
260 270 280 290 300
PPSPLPHSSP PTAAVATTSI TTATPGVPGL PSLAPSLLAA ALEGPYPVEE
310 320 330 340 350
IRLPRAGGPL GLSIVGGSDH SSHPFGVQEP GVFISKVLPR GLAARSGLRV
360 370 380 390 400
GDRILAVNGQ DVRDATHQEA VSALLRPCLE LSLLVRRDPA PPGLRELCIQ
410 420 430 440 450
KAPGERLGIS IRGGARGHAG NPRDPTDEGI FISKVSPTGA AGRDGRLRVG
460 470 480 490 500
LRLLEVNQQS LLGLTHGEAV QLLRSVGDTL TVLVCDGFEA STDAALEVSP
510 520 530 540 550
GVIANPFAAG IGHRNSLESI SSIDRELSPE GPGKEKELPG QTLHWGPEAT
560 570 580 590 600
EAAGRGLQPL KLDYRALAAV PSAGSVQRVP SGAAGGKMAE SPCSPSGQQP
610 620 630 640 650
PSPPSPDELP ANVKQAYRAF AAVPTSHPPE DAPAQPPTPG PAASPEQLSF
660 670 680
RERQKYFELE VRVPQAEGPV RPGRRGLGPV PS
Length:682
Mass (Da):70,924
Last modified:January 9, 2007 - v1
Checksum:i5A7CC0076191B87F
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC044627 mRNA. Translation: AAH44627.1.
RefSeqiNP_874365.3. NM_182706.4.
UniGeneiHs.436329.

Genome annotation databases

GeneIDi23513.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC044627 mRNA. Translation: AAH44627.1.
RefSeqiNP_874365.3. NM_182706.4.
UniGeneiHs.436329.

3D structure databases

ProteinModelPortaliA0PJK8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiA0PJK8. 1 interaction.
STRINGi9606.ENSP00000349486.

Proteomic databases

PaxDbiA0PJK8.
PeptideAtlasiA0PJK8.
PRIDEiA0PJK8.

Protocols and materials databases

DNASUi23513.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi23513.

Organism-specific databases

CTDi23513.
PharmGKBiPA134936275.

Phylogenomic databases

eggNOGiENOG410KCZ0. Eukaryota.
COG4886. LUCA.
HOGENOMiHOG000113281.

Miscellaneous databases

ChiTaRSiSCRIB. human.
GenomeRNAii23513.

Gene expression databases

GenevisibleiA0PJK8. HS.

Family and domain databases

Gene3Di2.30.42.10. 4 hits.
InterProiIPR001478. PDZ.
[Graphical view]
PfamiPF00595. PDZ. 4 hits.
[Graphical view]
SMARTiSM00228. PDZ. 4 hits.
[Graphical view]
SUPFAMiSSF50156. SSF50156. 4 hits.
PROSITEiPS50106. PDZ. 4 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: KidneyImported.

Entry informationi

Entry nameiA0PJK8_HUMAN
AccessioniPrimary (citable) accession number: A0PJK8
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: July 6, 2016
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.