ID   A0NZ53_ROSAI            Unreviewed;       343 AA.
AC   A0NZ53;
DT   09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2007, sequence version 1.
DT   03-MAY-2023, entry version 64.
DE   SubName: Full=Urea transporter {ECO:0000313|EMBL:EAV42054.1};
GN   ORFNames=SIAM614_25582 {ECO:0000313|EMBL:EAV42054.1};
OS   Roseibium aggregatum (strain ATCC 25650 / DSM 13394 / JCM 20685 / NBRC
OS   16684 / NCIMB 2208 / IAM 12614 / B1) (Stappia aggregata).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Stappiaceae; Roseibium.
OX   NCBI_TaxID=384765 {ECO:0000313|EMBL:EAV42054.1, ECO:0000313|Proteomes:UP000004848};
RN   [1] {ECO:0000313|EMBL:EAV42054.1, ECO:0000313|Proteomes:UP000004848}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25650 / DSM 13394 / JCM 20685 / NBRC 16684 / NCIMB 2208 /
RC   IAM 12614 / B1 {ECO:0000313|Proteomes:UP000004848};
RA   King G., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA   Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL   Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the urea transporter family.
CC       {ECO:0000256|ARBA:ARBA00005914}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAV42054.1}.
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DR   EMBL; AAUW01000017; EAV42054.1; -; Genomic_DNA.
DR   RefSeq; WP_006937938.1; NZ_AAUW01000017.1.
DR   AlphaFoldDB; A0NZ53; -.
DR   GeneID; 68848582; -.
DR   eggNOG; COG4413; Bacteria.
DR   OrthoDB; 279428at2; -.
DR   Proteomes; UP000004848; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015204; F:urea transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.10.3430.10; Ammonium transporter AmtB like domains; 1.
DR   InterPro; IPR029020; Ammonium/urea_transptr.
DR   InterPro; IPR004937; Urea_transporter.
DR   PANTHER; PTHR10464; UREA TRANSPORTER; 1.
DR   PANTHER; PTHR10464:SF4; UREA TRANSPORTER; 1.
DR   Pfam; PF03253; UT; 1.
DR   PIRSF; PIRSF016502; Urea_transporter; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        45..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        76..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        104..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        139..156
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        202..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        245..263
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        269..289
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        301..322
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   SITE            298
FT                   /note="Important for channel permeability"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR016502-1"
SQ   SEQUENCE   343 AA;  36256 MW;  93EF5A6249E6BBE5 CRC64;
     MTALKDHPVF GFADWCLRGI GQVVFQNNPV SGLIILGALF FNSPIYGAIA VFGVVVSTAT
     AVLLQADKGL IRDGLFGFNG ALVALALIAF TSEDFHYGAV PSAYLAVYIA FGSAMTAMVF
     TSLANLLGPH RVAPLTMPFV LVGWLFLFAV LKFHSIDAGP LAKPVSPTQY DGSVQYTLAT
     WYKGIGNAIG QIFFQDNWVS GYLIVLGIAV NSRISAIMAL LGANVAAFVA VVYGAPEGAI
     SDGLFGYNAA LTAIALGGFF LVLTPASALY TLFGVVVSTW LWASVAIFLE PIGMPVLTST
     FVIVTWLMLI GVNGFAALVP VAPADAVTPE VNRRRYLKAL REG
//