Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

AGAP012068-PA

Gene

AgaP_AGAP012068

Organism
Anopheles gambiae (African malaria mosquito)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Thiol proteaseSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
AGAP012068-PAImported
Gene namesi
ORF Names:AgaP_AGAP012068Imported
OrganismiAnopheles gambiae (African malaria mosquito)Imported
Taxonomic identifieri7165 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles
Proteomesi
  • UP000007062 Componenti: Chromosome 3L

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiA0NGM4.

Interactioni

Protein-protein interaction databases

STRINGi7165.AGAP012068-PA.

Structurei

3D structure databases

ProteinModelPortaliA0NGM4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini151 – 451Calpain catalyticInterPro annotationAdd BLAST301
Domaini660 – 678EF-handInterPro annotationAdd BLAST19
Domaini686 – 715EF-handInterPro annotationAdd BLAST30
Domaini716 – 751EF-handInterPro annotationAdd BLAST36
Domaini781 – 815EF-handInterPro annotationAdd BLAST35

Sequence similaritiesi

Belongs to the peptidase C2 family.SAAS annotation

Phylogenomic databases

eggNOGiKOG0045. Eukaryota.
ENOG410XP0B. LUCA.
HOGENOMiHOG000232035.
InParanoidiA0NGM4.
KOiK08585.
OMAiSETANSM.
OrthoDBiEOG091G049E.
PhylomeDBiA0NGM4.

Family and domain databases

CDDicd00214. Calpain_III. 1 hit.
cd00044. CysPc. 1 hit.
cd00051. EFh. 2 hits.
Gene3Di1.10.238.10. 2 hits.
InterProiIPR033883. C2_III.
IPR022684. Calpain_cysteine_protease.
IPR022682. Calpain_domain_III.
IPR022683. Calpain_III.
IPR011992. EF-hand-dom_pair.
IPR002048. EF_hand_dom.
IPR000169. Pept_cys_AS.
IPR001300. Peptidase_C2_calpain_cat.
[Graphical view]
PfamiPF01067. Calpain_III. 1 hit.
PF00648. Peptidase_C2. 1 hit.
[Graphical view]
PRINTSiPR00704. CALPAIN.
SMARTiSM00720. calpain_III. 1 hit.
SM00230. CysPc. 1 hit.
SM00054. EFh. 2 hits.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
SSF49758. SSF49758. 1 hit.
PROSITEiPS50203. CALPAIN_CAT. 1 hit.
PS50222. EF_HAND_2. 4 hits.
PS00139. THIOL_PROTEASE_CYS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

A0NGM4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
PAAFAQSPPA SQWPTVPTPG SSGYSSLNPS ISGQSLSYGF NPNVMPALPD
60 70 80 90 100
SGAGYPPAGN QLPYPTMGFA GFGSPMDYTM PNLPPPVPDA LLRGAEPAAA
110 120 130 140 150
TCEEIPFQSI SIPIAEGMFS PLGDRNAGQR SSFDVQDFYQ IRQQCLDNGT
160 170 180 190 200
LFEDPEFPAS ASSLMYSKRP DRHYEWLRPH EICDGPEFFV EGFSRFDVQQ
210 220 230 240 250
GELGDCWLLA ACANLTQDHK MFLRVVPEDN SFEDGYAGVF HFRFWQYGKW
260 270 280 290 300
VDVVIDDRLP TYRGQLIYMR SSEQNEFWSA LLEKAYAKLH GSYESLRGGT
310 320 330 340 350
TCEAMEDFTG GVAEMYDLKD QTPPNLFEII EKGFKRNSMF GCSIEADPHV
360 370 380 390 400
LEAETPEGLI RGHAYSITKI QLVDIETPGR SGKIPLIRLR NPWGNEAEWN
410 420 430 440 450
GPWSDKSPEW RYIPDEQKQE LGLNFDHDGE FWMSYRDFTR YFDRMEICNL
460 470 480 490 500
SPDSLSDDEM TRGKISWEMS MFEGEWAVGT TAGGCRNYLD TFWHNPQYVI
510 520 530 540 550
RLDDPDEDDE EGNCTVIIAL LQKNRRSRRN MGVECLTIGF AVYRVTERDL
560 570 580 590 600
AQKPLKMNFF KYNASAARSP AFINLREVSC RFKLPPGTYV IVPSTFEPNE
610 620 630 640 650
EGEFIIRVFS ETANSMMEND DNVGVGDLDD RIAPDVPGYV QPSPQRQAME
660 670 680 690 700
RLFLDVAGAD GEVDWVELKR ILDHSFRDDN ISSEGFSKDV CRAMVAMLDV
710 720 730 740 750
DHTGKLGFEE FQQLLTDIAK WKAVFKLYDT EGSGRLSPFQ LREALNSAGY
760 770 780 790 800
HLNNRILNAL VHRYGSRSGT IPFDDFIMCA VKIKTMIEIF RERDTDGTNQ
810
ATFSMDEWVE KTLYS
Length:815
Mass (Da):92,230
Last modified:October 23, 2007 - v2
Checksum:i5DED7ED8A62FB695
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAB01008986 Genomic DNA. Translation: EAU75819.2.
RefSeqiXP_001238322.2. XM_001238321.2.

Genome annotation databases

EnsemblMetazoaiAGAP012068-RA; AGAP012068-PA; AGAP012068.
GeneIDi4577493.
KEGGiaga:AgaP_AGAP012068.
VectorBaseiAGAP012068-RA; AGAP012068-PA; AGAP012068.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAB01008986 Genomic DNA. Translation: EAU75819.2.
RefSeqiXP_001238322.2. XM_001238321.2.

3D structure databases

ProteinModelPortaliA0NGM4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7165.AGAP012068-PA.

Proteomic databases

PaxDbiA0NGM4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiAGAP012068-RA; AGAP012068-PA; AGAP012068.
GeneIDi4577493.
KEGGiaga:AgaP_AGAP012068.
VectorBaseiAGAP012068-RA; AGAP012068-PA; AGAP012068.

Phylogenomic databases

eggNOGiKOG0045. Eukaryota.
ENOG410XP0B. LUCA.
HOGENOMiHOG000232035.
InParanoidiA0NGM4.
KOiK08585.
OMAiSETANSM.
OrthoDBiEOG091G049E.
PhylomeDBiA0NGM4.

Family and domain databases

CDDicd00214. Calpain_III. 1 hit.
cd00044. CysPc. 1 hit.
cd00051. EFh. 2 hits.
Gene3Di1.10.238.10. 2 hits.
InterProiIPR033883. C2_III.
IPR022684. Calpain_cysteine_protease.
IPR022682. Calpain_domain_III.
IPR022683. Calpain_III.
IPR011992. EF-hand-dom_pair.
IPR002048. EF_hand_dom.
IPR000169. Pept_cys_AS.
IPR001300. Peptidase_C2_calpain_cat.
[Graphical view]
PfamiPF01067. Calpain_III. 1 hit.
PF00648. Peptidase_C2. 1 hit.
[Graphical view]
PRINTSiPR00704. CALPAIN.
SMARTiSM00720. calpain_III. 1 hit.
SM00230. CysPc. 1 hit.
SM00054. EFh. 2 hits.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
SSF49758. SSF49758. 1 hit.
PROSITEiPS50203. CALPAIN_CAT. 1 hit.
PS50222. EF_HAND_2. 4 hits.
PS00139. THIOL_PROTEASE_CYS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA0NGM4_ANOGA
AccessioniPrimary (citable) accession number: A0NGM4
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: October 23, 2007
Last modified: November 30, 2016
This is version 79 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.