UniProtKB - A0NFV2 (A0NFV2_ANOGA)
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Protein
Angiotensin-converting enzyme
Gene
ANCE5
Organism
Anopheles gambiae (African malaria mosquito)
Status
Functioni
Cofactori
Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation
GO - Molecular functioni
- carboxypeptidase activity Source: UniProtKB-KW
- metal ion binding Source: UniProtKB-KW
- metallopeptidase activity Source: UniProtKB-KW
- peptidyl-dipeptidase activity Source: InterPro
Keywordsi
Molecular function | CarboxypeptidaseUniRule annotation, Hydrolase, MetalloproteaseUniRule annotation, Protease |
Ligand | Metal-bindingUniRule annotation, ZincUniRule annotation |
Protein family/group databases
MEROPSi | M02.003 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:ANCE5Imported Synonyms:4578342Imported ORF Names:AgaP_AGAP009755Imported |
Organismi | Anopheles gambiae (African malaria mosquito)Imported |
Taxonomic identifieri | 7165 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Nematocera › Culicoidea › Culicidae › Anophelinae › Anopheles › |
Proteomesi |
|
Subcellular locationi
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 19 | Sequence analysisAdd BLAST | 19 | |
ChainiPRO_5014296666 | 20 – 620 | Angiotensin-converting enzymeSequence analysisAdd BLAST | 601 |
Keywords - PTMi
GlycoproteinUniRule annotationFamily & Domainsi
Sequence similaritiesi
Belongs to the peptidase M2 family.UniRule annotation
Keywords - Domaini
SignalSequence analysisPhylogenomic databases
eggNOGi | KOG3690 Eukaryota ENOG410XPJ3 LUCA |
HOGENOMi | HOG000292210 |
InParanoidi | A0NFV2 |
KOi | K01283 |
OMAi | GPCLPLE |
OrthoDBi | EOG091G033S |
PhylomeDBi | A0NFV2 |
Family and domain databases
CDDi | cd06461 M2_ACE, 1 hit |
InterProi | View protein in InterPro IPR001548 Peptidase_M2 |
PANTHERi | PTHR10514 PTHR10514, 1 hit |
Pfami | View protein in Pfam PF01401 Peptidase_M2, 1 hit |
PRINTSi | PR00791 PEPDIPTASEA |
i Sequence
Sequence statusi: Complete.
A0NFV2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRIFSTVIIA FALVCCVLGG KLVSVSDDEL EARHYVEQVD EEILSRRNVG
60 70 80 90 100
TEAEWAYESD INEDNLMVKN EVAAANAMFL KEVANTLNKY EYESFSDEDL
110 120 130 140 150
KRKIRKLTKL GYSVLPEDTF AEMLDAINRM QENYAKVKVC DYRDNSKCDL
160 170 180 190 200
ALEPELTEIM ATSRDPEELK YYWQQWYDAA GAPTRDDFQK YVDLNGVAAR
210 220 230 240 250
MNNYSSGAEY WLSAYEDDTF EEQVDAVIEE LRPLYEQIHA NVRYQLRKYY
260 270 280 290 300
GEDVVSEKGP IPMHLLGNMW AQDWAGVADI ISPFPDRQLL DVTEEMVRQG
310 320 330 340 350
YNPIQMFEMG DEFFQSMNMT KLPATFWEKS ILEKPDDGRD LVCHASAWEF
360 370 380 390 400
SKTDDVRIKQ CTRVTMEQFF TVHHELGHVQ YFLQYQHLPS MYRDGANPGF
410 420 430 440 450
HEAVGDVLSL SVSTPKHLEK IGLLKDYVED EESKLNQFYG SALNKLVFLP
460 470 480 490 500
FAYTLDKYRW GIFRGDIKPE EYNCKFWEMR SKFSGVEPPV VRSESDLDAP
510 520 530 540 550
AKYHVSADVE YLRYFVSFII QFQFHRAACE KAGEYVKGDP EKTLNNCDIY
560 570 580 590 600
QSVEAGNAIK AMLELGSSKP WPDAMEVLTG ERRMSADALI EYFQPLYDWL
610 620
VVENERIGAH VGWEETESKF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAAB01008980 Genomic DNA Translation: EAU76041.1 |
RefSeqi | XP_001238057.1, XM_001238056.1 |
Genome annotation databases
EnsemblMetazoai | AGAP009755-RA; AGAP009755-PA; AGAP009755 |
GeneIDi | 4578342 |
KEGGi | aga:AgaP_AGAP009755 |
VectorBasei | AGAP009755-RA; AGAP009755-PA; AGAP009755 |
Similar proteinsi
Entry informationi
Entry namei | A0NFV2_ANOGA | |
Accessioni | A0NFV2Primary (citable) accession number: A0NFV2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | January 9, 2007 |
Last sequence update: | January 9, 2007 | |
Last modified: | April 25, 2018 | |
This is version 82 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |