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Protein

Angiotensin-converting enzyme

Gene

ANCE5

Organism
Anopheles gambiae (African malaria mosquito)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionCarboxypeptidaseUniRule annotation, Hydrolase, MetalloproteaseUniRule annotation, Protease
LigandMetal-bindingUniRule annotation, ZincUniRule annotation

Protein family/group databases

MEROPSiM02.003.

Names & Taxonomyi

Protein namesi
Recommended name:
Angiotensin-converting enzymeUniRule annotation (EC:3.4.-.-UniRule annotation)
Gene namesi
Name:ANCE5Imported
Synonyms:4578342Imported
ORF Names:AgaP_AGAP009755Imported
OrganismiAnopheles gambiae (African malaria mosquito)Imported
Taxonomic identifieri7165 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles
Proteomesi
  • UP000007062 Componenti: Chromosome 3R

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_501081997920 – 620Angiotensin-converting enzymeSequence analysisAdd BLAST601

Keywords - PTMi

GlycoproteinUniRule annotation

Proteomic databases

PaxDbiA0NFV2.

Interactioni

Protein-protein interaction databases

STRINGi7165.AGAP009755-PA.

Structurei

3D structure databases

ProteinModelPortaliA0NFV2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M2 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3690. Eukaryota.
ENOG410XPJ3. LUCA.
HOGENOMiHOG000292210.
InParanoidiA0NFV2.
KOiK01283.
OMAiGPCLPLE.
OrthoDBiEOG091G033S.
PhylomeDBiA0NFV2.

Family and domain databases

CDDicd06461. M2_ACE. 1 hit.
InterProiView protein in InterPro
IPR001548. Peptidase_M2.
PANTHERiPTHR10514. PTHR10514. 1 hit.
PfamiView protein in Pfam
PF01401. Peptidase_M2. 1 hit.
PRINTSiPR00791. PEPDIPTASEA.

Sequencei

Sequence statusi: Complete.

A0NFV2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRIFSTVIIA FALVCCVLGG KLVSVSDDEL EARHYVEQVD EEILSRRNVG
60 70 80 90 100
TEAEWAYESD INEDNLMVKN EVAAANAMFL KEVANTLNKY EYESFSDEDL
110 120 130 140 150
KRKIRKLTKL GYSVLPEDTF AEMLDAINRM QENYAKVKVC DYRDNSKCDL
160 170 180 190 200
ALEPELTEIM ATSRDPEELK YYWQQWYDAA GAPTRDDFQK YVDLNGVAAR
210 220 230 240 250
MNNYSSGAEY WLSAYEDDTF EEQVDAVIEE LRPLYEQIHA NVRYQLRKYY
260 270 280 290 300
GEDVVSEKGP IPMHLLGNMW AQDWAGVADI ISPFPDRQLL DVTEEMVRQG
310 320 330 340 350
YNPIQMFEMG DEFFQSMNMT KLPATFWEKS ILEKPDDGRD LVCHASAWEF
360 370 380 390 400
SKTDDVRIKQ CTRVTMEQFF TVHHELGHVQ YFLQYQHLPS MYRDGANPGF
410 420 430 440 450
HEAVGDVLSL SVSTPKHLEK IGLLKDYVED EESKLNQFYG SALNKLVFLP
460 470 480 490 500
FAYTLDKYRW GIFRGDIKPE EYNCKFWEMR SKFSGVEPPV VRSESDLDAP
510 520 530 540 550
AKYHVSADVE YLRYFVSFII QFQFHRAACE KAGEYVKGDP EKTLNNCDIY
560 570 580 590 600
QSVEAGNAIK AMLELGSSKP WPDAMEVLTG ERRMSADALI EYFQPLYDWL
610 620
VVENERIGAH VGWEETESKF
Length:620
Mass (Da):71,777
Last modified:January 9, 2007 - v1
Checksum:i5BD0EC4CE0FBA8B7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAB01008980 Genomic DNA. Translation: EAU76041.1.
RefSeqiXP_001238057.1. XM_001238056.1.

Genome annotation databases

EnsemblMetazoaiAGAP009755-RA; AGAP009755-PA; AGAP009755.
GeneIDi4578342.
KEGGiaga:AgaP_AGAP009755.
VectorBaseiAGAP009755-RA; AGAP009755-PA; AGAP009755.

Similar proteinsi

Entry informationi

Entry nameiA0NFV2_ANOGA
AccessioniPrimary (citable) accession number: A0NFV2
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: August 30, 2017
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported