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Protein
Submitted name:

AGAP009754-PA

Gene

ANCE4

Organism
Anopheles gambiae (African malaria mosquito)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Cofactori

Protein has several cofactor binding sites:
  • Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation
  • Zn2+UniRule annotationNote: Binds 2 Zn2+ ions per subunit.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

CarboxypeptidaseUniRule annotation, Hydrolase, MetalloproteaseUniRule annotation, Protease

Keywords - Ligandi

Metal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
AGAP009754-PAImported
Gene namesi
Name:ANCE4Imported
ORF Names:AgaP_AGAP009754Imported
OrganismiAnopheles gambiae (African malaria mosquito)Imported
Taxonomic identifieri7165 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles
ProteomesiUP000007062 Componenti: Chromosome 3R

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Keywords - PTMi

GlycoproteinUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi7165.AGAP009754-PA.

Structurei

3D structure databases

ProteinModelPortaliA0NFV1.
SMRiA0NFV1. Positions 36-622.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M2 family.UniRule annotation

Phylogenomic databases

eggNOGiNOG71044.
HOGENOMiHOG000292210.
InParanoidiA0NFV1.
KOiK01283.
OMAiNEVATEN.
OrthoDBiEOG7N37C7.
PhylomeDBiA0NFV1.

Family and domain databases

InterProiIPR001548. Peptidase_M2.
[Graphical view]
PANTHERiPTHR10514. PTHR10514. 1 hit.
PfamiPF01401. Peptidase_M2. 1 hit.
[Graphical view]
PRINTSiPR00791. PEPDIPTASEA.

Sequencei

Sequence statusi: Complete.

A0NFV1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRVVLLVSLA IGLVCHVSTA RIPRRVLQAQ EEEVFQYLED IEPEILARRN
60 70 80 90 100
AASEANWAYD SNITDDNLDV KNEVATENAA FFKQISEYLS QFEYESFENE
110 120 130 140 150
NLKRRVKKLV GLGYSALPEE KFTEMLDAIN NMKENYAKIK VCDYHDRSKC
160 170 180 190 200
DLALEPELTE ILANSRDAEE LKYYWQQWYD AAGTPTREDF QTYVELNGEA
210 220 230 240 250
AKLNNYESGA DSWLSAYEDD TFEEQVDAVI EELRPFYEQI HAYVRYRLRE
260 270 280 290 300
FYGEDVVSEK GPIPMHLLGN MWAQGWENIA EITSPFGDRE MFDVTEEMVR
310 320 330 340 350
QGYTPVQMFE MGDEFFQSLN MTKLPQTFWE KSILEKPDDG RDLICHASAW
360 370 380 390 400
DFSKPDDVRI KQCTRVTMDQ FFTAHHELGH IQYYLQYQHQ PSVYRSGANP
410 420 430 440 450
GFHEAVGDVL SLSVSTPKHL EKIGLLKDYV QDEESKLNQF YQAGLSKLVF
460 470 480 490 500
LPFAYTLDKY RWGIFRGDIK PEEYNCKFWE MRSKYSGIEP PVVRTEADFD
510 520 530 540 550
APAKYHVSAD VEYLRYFVSY IIQFQFHRAA CEKAGEYVKG DPEKTLNDCD
560 570 580 590 600
IYQSTEAGNA IKAMLELGSS KPWPDAMEVL TGERRMSADA LIEYFQPLYD
610 620
WLVVENERIG AHVGWEETDS KCEV
Length:624
Mass (Da):72,474
Last modified:October 23, 2007 - v2
Checksum:i2E98A4E89F205DFF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAB01008980 Genomic DNA. Translation: EAU76040.2.
RefSeqiXP_001238056.2. XM_001238055.2.

Genome annotation databases

EnsemblMetazoaiAGAP009754-RA; AGAP009754-PA; AGAP009754.
GeneIDi4578145.
KEGGiaga:AgaP_AGAP009754.
VectorBaseiAGAP009753. Anopheles gambiae.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAB01008980 Genomic DNA. Translation: EAU76040.2.
RefSeqiXP_001238056.2. XM_001238055.2.

3D structure databases

ProteinModelPortaliA0NFV1.
SMRiA0NFV1. Positions 36-622.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7165.AGAP009754-PA.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiAGAP009754-RA; AGAP009754-PA; AGAP009754.
GeneIDi4578145.
KEGGiaga:AgaP_AGAP009754.
VectorBaseiAGAP009753. Anopheles gambiae.

Organism-specific databases

CTDi4578145.

Phylogenomic databases

eggNOGiNOG71044.
HOGENOMiHOG000292210.
InParanoidiA0NFV1.
KOiK01283.
OMAiNEVATEN.
OrthoDBiEOG7N37C7.
PhylomeDBiA0NFV1.

Family and domain databases

InterProiIPR001548. Peptidase_M2.
[Graphical view]
PANTHERiPTHR10514. PTHR10514. 1 hit.
PfamiPF01401. Peptidase_M2. 1 hit.
[Graphical view]
PRINTSiPR00791. PEPDIPTASEA.
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of the malaria mosquito Anopheles gambiae."
    Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R., Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M., Wides R., Salzberg S.L., Loftus B., Yandell M., Majoros W.H., Rusch D.B., Lai Z., Kraft C.L., Abril J.F.
    , Anthouard V., Arensburger P., Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K., Christophides G.K., Chrystal M.A., Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I., Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C., Kokoza E., Koutsos A., Letunic I., Levitsky A., Liang Y., Lin J.J., Lobo N.F., Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J., Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D., Ton L.Q., Topalis P., Tu Z., Unger M.F., Walenz B., Wang A., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I., Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L.
    Science 298:129-149(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PESTImported.

Entry informationi

Entry nameiA0NFV1_ANOGA
AccessioniPrimary (citable) accession number: A0NFV1
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: October 23, 2007
Last modified: July 22, 2015
This is version 59 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.