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Protein

Angiotensin-converting enzyme

Gene

ANCE2

Organism
Anopheles gambiae (African malaria mosquito)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionCarboxypeptidaseUniRule annotation, Hydrolase, MetalloproteaseUniRule annotation, Protease
LigandMetal-bindingUniRule annotation, ZincUniRule annotation

Protein family/group databases

MEROPSiM02.003.

Names & Taxonomyi

Protein namesi
Recommended name:
Angiotensin-converting enzymeUniRule annotation (EC:3.4.-.-UniRule annotation)
Gene namesi
Name:ANCE2Imported
Synonyms:4578020Imported
ORF Names:AgaP_AGAP009751Imported
OrganismiAnopheles gambiae (African malaria mosquito)Imported
Taxonomic identifieri7165 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles
Proteomesi
  • UP000007062 Componenti: Chromosome 3R

Subcellular locationi

PTM / Processingi

Keywords - PTMi

GlycoproteinUniRule annotation

Proteomic databases

PaxDbiA0NFU8.

Interactioni

Protein-protein interaction databases

STRINGi7165.AGAP009751-PA.

Structurei

3D structure databases

ProteinModelPortaliA0NFU8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M2 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3690. Eukaryota.
ENOG410XPJ3. LUCA.
HOGENOMiHOG000292210.
InParanoidiA0NFU8.
KOiK01283.
OMAiSAWDFYQ.
OrthoDBiEOG091G033S.
PhylomeDBiA0NFU8.

Family and domain databases

CDDicd06461. M2_ACE. 1 hit.
InterProiView protein in InterPro
IPR001548. Peptidase_M2.
PANTHERiPTHR10514. PTHR10514. 1 hit.
PfamiView protein in Pfam
PF01401. Peptidase_M2. 1 hit.
PRINTSiPR00791. PEPDIPTASEA.

Sequencei

Sequence statusi: Fragment.

A0NFU8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
NRFGITCKGL FIPSVQQYVS DGDSANSSSR PVFPVQVLIN GLAETIQWDW
60 70 80 90 100
NVRRDSEKHI MASNIQWRSV WLMLLFASTI AAGPVKRRST ESEKAPSETE
110 120 130 140 150
ISQIVEWIEQ RYQQTKAHQT LAAWEYGSNL TEFNLSKKTK AAADFAEVAK
160 170 180 190 200
AVAEELQQFK TDQLTNATLK RRIKKLAKLG YAALPADQFK ELLGAIASME
210 220 230 240 250
SNYAKAKFCA YGDATKCDLS LDPELTEIFA NHREPEELKY YWVQWYNATG
260 270 280 290 300
APVRESFQKY VELNRQAALR NNFSSGAAVW LNEYDDSTFE QQVDDVIEQI
310 320 330 340 350
RPLYEQLHAY VRYKLRQKYG DKLVSPTGPI PMHLLGNLWA QTWDNIADFT
360 370 380 390 400
TPFPEKKLLD VTDEMIRQGY TPIKMFQMGD DFFTSLNMTK LPQTFWDKSI
410 420 430 440 450
LEKPTDGRDL VCHASAWDFF AIDDVRIKQC TRVNMREFFV VHHELGHIQY
460 470 480 490 500
YLQYQHQPVE FRGGANPGFH EAVGDVLSLS VSTPKHLKKV GLLKDYEEDE
510 520 530 540 550
QVKINQFYRA GVTKLVFLPF AYTLDKYRWG VFRGDIKPRE YNCKFWEMRS
560 570 580 590 600
RYSGVEPPVV RTEQDFDPPA KYHVSADVEY LRYFVSYVIQ FQFHRAACAL
610 620 630 640 650
AGEYVKGDPE KTLNNCDIYQ STAAGNQLKE MLALGSSKPW PDAMEVLTGE
660 670 680 690
RKMSADAILE YFDPLYQWLL EENKRLGAHV GWTDSQKCVS HPIDFMAA
Length:698
Mass (Da):80,352
Last modified:October 23, 2007 - v2
Checksum:i3C065DAB2F956C5B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAB01008980 Genomic DNA. Translation: EAU76037.2.
RefSeqiXP_001238053.2. XM_001238052.2.

Genome annotation databases

EnsemblMetazoaiAGAP009751-RA; AGAP009751-PA; AGAP009751.
GeneIDi4578020.
KEGGiaga:AgaP_AGAP009751.
VectorBaseiAGAP009751-RA; AGAP009751-PA; AGAP009751.

Similar proteinsi

Entry informationi

Entry nameiA0NFU8_ANOGA
AccessioniPrimary (citable) accession number: A0NFU8
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: October 23, 2007
Last modified: October 25, 2017
This is version 79 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported