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Protein
Submitted name:

Insulin-like growth factor type II receptor

Gene

IGF2R

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: Ensembl
  2. mannose binding Source: Ensembl
  3. retinoic acid binding Source: Ensembl

GO - Biological processi

  1. liver development Source: Ensembl
  2. organ regeneration Source: Ensembl
  3. positive regulation of apoptotic process Source: Ensembl
  4. post-embryonic development Source: Ensembl
  5. response to retinoic acid Source: Ensembl
  6. spermatogenesis Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Insulin-like growth factor type II receptorImported
Gene namesi
Name:IGF2RImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. clathrin coat Source: Ensembl
  2. extracellular space Source: Ensembl
  3. late endosome Source: Ensembl
  4. nuclear envelope lumen Source: Ensembl
  5. perinuclear region of cytoplasm Source: Ensembl
  6. plasma membrane Source: Ensembl
  7. trans-Golgi network Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiA0N9R7.

Expressioni

Gene expression databases

BgeeiA0N9R7.
ExpressionAtlasiA0N9R7. baseline and differential.

Family & Domainsi

Family and domain databases

Gene3Di2.70.130.10. 1 hit.
InterProiIPR009011. Man6P_isomerase_rcpt-bd_dom.
[Graphical view]
SUPFAMiSSF50911. SSF50911. 1 hit.

Sequencei

Sequence statusi: Fragment.

A0N9R7-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40 
EAVDTKNNVL YKINICGSVD IVQCGPSSAV CMHDLKTRTY HSV
Length:43
Mass (Da):4,710
Last modified:December 12, 2006 - v1
Checksum:iB35667D3B01D15D9
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei43 – 431Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X83700 Genomic DNA. Translation: CAA58673.2.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X83700 Genomic DNA. Translation: CAA58673.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiA0N9R7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

ChiTaRSiIGF2R. human.
NextBioi35460099.

Gene expression databases

BgeeiA0N9R7.
ExpressionAtlasiA0N9R7. baseline and differential.

Family and domain databases

Gene3Di2.70.130.10. 1 hit.
InterProiIPR009011. Man6P_isomerase_rcpt-bd_dom.
[Graphical view]
SUPFAMiSSF50911. SSF50911. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Conservation of a methylation imprint and a putative imprinting box at the human IGF2R locus."
    Smrzka O.W., Fae I., Stoger R., Kurzbauer R., Fischer G.F., Henn T., Weith A., Barlow D.P.
    Hum. Mol. Genet. 4:1945-1952(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: PBLImported.

Entry informationi

Entry nameiA0N9R7_HUMAN
AccessioniPrimary (citable) accession number: A0N9R7
Entry historyi
Integrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: November 26, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.