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A0N9R6

- A0N9R6_HUMAN

UniProt

A0N9R6 - A0N9R6_HUMAN

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Protein
Submitted name: Insulin-like growth factor type 2 receptor
Gene
IGF2R, igf2R
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: Ensembl
  2. mannose binding Source: Ensembl
  3. retinoic acid binding Source: Ensembl

GO - Biological processi

  1. liver development Source: Ensembl
  2. organ regeneration Source: Ensembl
  3. positive regulation of apoptotic process Source: Ensembl
  4. post-embryonic development Source: Ensembl
  5. response to retinoic acid Source: Ensembl
  6. spermatogenesis Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Insulin-like growth factor type 2 receptorImported
Submitted name:
Insulin-like growth factor type II receptorImported
Gene namesi
Name:IGF2RImported
Synonyms:igf2RImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. clathrin coat Source: Ensembl
  2. extracellular space Source: Ensembl
  3. late endosome Source: Ensembl
  4. nuclear envelope lumen Source: Ensembl
  5. perinuclear region of cytoplasm Source: Ensembl
  6. plasma membrane Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiA0N9R6.

Sequencei

Sequence statusi: Fragment.

A0N9R6-1 [UniParc]FASTAAdd to Basket

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MGAAAGRSPH LGPAPARRPQ RSLLLLQLLL LVAAPGSTQA QAAPFPELC    49
Length:49
Mass (Da):5,015
Last modified:December 12, 2006 - v1
Checksum:iC0824C7F0946FEBA
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei49 – 491Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X83699 Genomic DNA. Translation: CAA58672.1.
X91875 Genomic DNA. Translation: CAA62977.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X83699 Genomic DNA. Translation: CAA58672.1 .
X91875 Genomic DNA. Translation: CAA62977.1 .

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

H-InvDB HIX0033007.

Miscellaneous databases

ChiTaRSi IGF2R. human.
NextBioi 35460098.

Gene expression databases

ArrayExpressi A0N9R6.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "Insulin-like growth factor II receptor as a multifunctional binding protein."
    Morgan D.O., Edman J.C., Standring D.N., Fried V.A., Smith M.C., Roth R.A., Rutter W.J.
    Nature 329:301-307(1987) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: PBLImported.
  2. "The human cation-independent mannose 6-phosphate receptor. Cloning and sequence of the full-length cDNA and expression of functional receptor in COS cells."
    Oshima A., Nolan C.M., Kyle J.W., Grubb J.H., Sly W.S.
    J. Biol. Chem. 263:2553-2562(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: PBLImported.
  3. "Conservation of a methylation imprint and a putative imprinting box at the human IGF2R locus."
    Smrzka O.W., Fae I., Stoger R., Kurzbauer R., Fischer G.F., Henn T., Weith A., Barlow D.P.
    Hum. Mol. Genet. 4:1945-1952(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: PBLImported.
  4. Kalscheuer V.M.M.
    Submitted (SEP-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  5. "Maternal-specific methylation of the human IGF2R gene is not accompanied by allele-specific transcription."
    Riesewijk A.M., Schepens M.T., Welch T.R., van den Berg-Loonen E.M., Mariman E.M., Ropers H.H., Kalscheuer V.M.
    Genomics 31:158-166(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiA0N9R6_HUMAN
AccessioniPrimary (citable) accession number: A0N9R6
Entry historyi
Integrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: July 9, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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