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A0N9R6

- A0N9R6_HUMAN

UniProt

A0N9R6 - A0N9R6_HUMAN

Protein
Submitted name:

Insulin-like growth factor type 2 receptor

Gene

IGF2R

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. G-protein coupled receptor activity Source: Ensembl
    2. mannose binding Source: Ensembl
    3. retinoic acid binding Source: Ensembl

    GO - Biological processi

    1. liver development Source: Ensembl
    2. organ regeneration Source: Ensembl
    3. positive regulation of apoptotic process Source: Ensembl
    4. post-embryonic development Source: Ensembl
    5. response to retinoic acid Source: Ensembl
    6. spermatogenesis Source: Ensembl

    Keywords - Molecular functioni

    ReceptorImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Insulin-like growth factor type 2 receptorImported
    Submitted name:
    Insulin-like growth factor type II receptorImported
    Gene namesi
    Name:IGF2RImported
    Synonyms:igf2RImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. clathrin coat Source: Ensembl
    2. extracellular space Source: Ensembl
    3. late endosome Source: Ensembl
    4. nuclear envelope lumen Source: Ensembl
    5. perinuclear region of cytoplasm Source: Ensembl
    6. plasma membrane Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiA0N9R6.

    Sequencei

    Sequence statusi: Fragment.

    A0N9R6-1 [UniParc]FASTAAdd to Basket

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    MGAAAGRSPH LGPAPARRPQ RSLLLLQLLL LVAAPGSTQA QAAPFPELC    49
    Length:49
    Mass (Da):5,015
    Last modified:December 12, 2006 - v1
    Checksum:iC0824C7F0946FEBA
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei49 – 491Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X83699 Genomic DNA. Translation: CAA58672.1.
    X91875 Genomic DNA. Translation: CAA62977.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X83699 Genomic DNA. Translation: CAA58672.1 .
    X91875 Genomic DNA. Translation: CAA62977.1 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    H-InvDB HIX0033007.

    Miscellaneous databases

    ChiTaRSi IGF2R. human.
    NextBioi 35460098.

    Gene expression databases

    ArrayExpressi A0N9R6.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Insulin-like growth factor II receptor as a multifunctional binding protein."
      Morgan D.O., Edman J.C., Standring D.N., Fried V.A., Smith M.C., Roth R.A., Rutter W.J.
      Nature 329:301-307(1987) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: PBLImported.
    2. "The human cation-independent mannose 6-phosphate receptor. Cloning and sequence of the full-length cDNA and expression of functional receptor in COS cells."
      Oshima A., Nolan C.M., Kyle J.W., Grubb J.H., Sly W.S.
      J. Biol. Chem. 263:2553-2562(1988) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: PBLImported.
    3. "Conservation of a methylation imprint and a putative imprinting box at the human IGF2R locus."
      Smrzka O.W., Fae I., Stoger R., Kurzbauer R., Fischer G.F., Henn T., Weith A., Barlow D.P.
      Hum. Mol. Genet. 4:1945-1952(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: PBLImported.
    4. Kalscheuer V.M.M.
      Submitted (SEP-1995) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    5. "Maternal-specific methylation of the human IGF2R gene is not accompanied by allele-specific transcription."
      Riesewijk A.M., Schepens M.T., Welch T.R., van den Berg-Loonen E.M., Mariman E.M., Ropers H.H., Kalscheuer V.M.
      Genomics 31:158-166(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiA0N9R6_HUMAN
    AccessioniPrimary (citable) accession number: A0N9R6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 12, 2006
    Last sequence update: December 12, 2006
    Last modified: October 1, 2014
    This is version 33 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.