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A0N0D0

- A0N0D0_MOUSE

UniProt

A0N0D0 - A0N0D0_MOUSE

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Protein
Submitted name:

Peroxisome proliferator activated receptor gamma 2

Gene

Pparg

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. drug binding Source: Ensembl
  2. ligand-dependent nuclear receptor transcription coactivator activity Source: Ensembl
  3. transcription regulatory region DNA binding Source: Ensembl

GO - Biological processi

  1. activation of cysteine-type endopeptidase activity involved in apoptotic process Source: Ensembl
  2. cell maturation Source: Ensembl
  3. cellular response to hyperoxia Source: Ensembl
  4. cellular response to insulin stimulus Source: Ensembl
  5. cellular response to prostaglandin E stimulus Source: Ensembl
  6. cellular response to retinoic acid Source: Ensembl
  7. cellular response to vitamin E Source: Ensembl
  8. fatty acid oxidation Source: Ensembl
  9. glucose homeostasis Source: Ensembl
  10. heart development Source: Ensembl
  11. lipoprotein transport Source: Ensembl
  12. low-density lipoprotein particle receptor biosynthetic process Source: Ensembl
  13. monocyte differentiation Source: Ensembl
  14. negative regulation of acute inflammatory response Source: Ensembl
  15. negative regulation of cell growth Source: Ensembl
  16. negative regulation of cholesterol storage Source: Ensembl
  17. negative regulation of collagen biosynthetic process Source: Ensembl
  18. negative regulation of interferon-gamma-mediated signaling pathway Source: Ensembl
  19. negative regulation of pancreatic stellate cell proliferation Source: Ensembl
  20. negative regulation of receptor biosynthetic process Source: Ensembl
  21. negative regulation of sequestering of triglyceride Source: Ensembl
  22. negative regulation of smooth muscle cell proliferation Source: Ensembl
  23. negative regulation of telomerase activity Source: Ensembl
  24. organ regeneration Source: Ensembl
  25. peroxisome proliferator activated receptor signaling pathway Source: Ensembl
  26. positive regulation of apoptotic process Source: Ensembl
  27. positive regulation of fatty acid oxidation Source: Ensembl
  28. positive regulation of oligodendrocyte differentiation Source: Ensembl
  29. positive regulation of phagocytosis, engulfment Source: Ensembl
  30. positive regulation of sequence-specific DNA binding transcription factor activity Source: Ensembl
  31. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
  32. regulation of blood pressure Source: Ensembl
  33. regulation of fat cell differentiation Source: Ensembl
  34. response to caffeine Source: Ensembl
  35. response to cold Source: Ensembl
  36. response to diuretic Source: Ensembl
  37. response to estrogen Source: Ensembl
  38. response to immobilization stress Source: Ensembl
  39. response to low-density lipoprotein particle Source: Ensembl
  40. response to mechanical stimulus Source: Ensembl
  41. response to metformin Source: Ensembl
  42. response to starvation Source: Ensembl
  43. response to vitamin A Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Enzyme and pathway databases

ReactomeiREACT_198602. PPARA activates gene expression.
REACT_234105. Nuclear Receptor transcription pathway.
REACT_252217. Transcriptional regulation of white adipocyte differentiation.

Names & Taxonomyi

Protein namesi
Submitted name:
Peroxisome proliferator activated receptor gamma 2Imported
Gene namesi
Name:PpargImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: Ensembl
  2. perinuclear region of cytoplasm Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiA0N0D0.
ExpressionAtlasiA0N0D0. baseline and differential.
GenevestigatoriA0N0D0.

Sequencei

Sequence statusi: Fragment.

A0N0D0-1 [UniParc]FASTAAdd to Basket

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        10         20 
MGETLGDSPV DPEHGAFADA LPMSTS
Length:26
Mass (Da):2,633
Last modified:December 12, 2006 - v1
Checksum:i2CC1FA0E15392FA8
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei26 – 261Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF062479 Genomic DNA. Translation: ABK39950.1.
UniGeneiMm.3020.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF062479 Genomic DNA. Translation: ABK39950.1 .
UniGenei Mm.3020.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

Reactomei REACT_198602. PPARA activates gene expression.
REACT_234105. Nuclear Receptor transcription pathway.
REACT_252217. Transcriptional regulation of white adipocyte differentiation.

Miscellaneous databases

NextBioi 35542228.

Gene expression databases

Bgeei A0N0D0.
ExpressionAtlasi A0N0D0. baseline and differential.
Genevestigatori A0N0D0.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. Ackert-Bicknell C.L., Rosen C.J.
    Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C3H/HeJImported.

Entry informationi

Entry nameiA0N0D0_MOUSE
AccessioniPrimary (citable) accession number: A0N0D0
Entry historyi
Integrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: November 26, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)