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Protein
Submitted name:

CDW11/WDR57

Gene

WDR57

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
CDW11/WDR57Imported
Submitted name:
WD repeat domain 57 (U5 snRNP specific), isoform CRA_aImported
Submitted name:
cDNA FLJ90035 fis, clone HEMBA1001878, highly similar to WD repeat protein 57Imported
Gene namesi
Name:WDR57Imported
ORF Names:hCG_20041Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000060688.12

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA164726132

PTM / Processingi

Proteomic databases

PRIDEiA0MNP2

Expressioni

Gene expression databases

BgeeiENSG00000060688
ExpressionAtlasiA0MNP2 baseline and differential

Structurei

3D structure databases

SMRiA0MNP2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini62 – 357WD_REPEATS_REGIONInterPro annotationAdd BLAST296
Repeati62 – 95WDPROSITE-ProRule annotationAdd BLAST34
Repeati105 – 146WDPROSITE-ProRule annotationAdd BLAST42
Repeati147 – 189WDPROSITE-ProRule annotationAdd BLAST43
Repeati189 – 230WDPROSITE-ProRule annotationAdd BLAST42
Repeati231 – 265WDPROSITE-ProRule annotationAdd BLAST35
Repeati292 – 322WDPROSITE-ProRule annotationAdd BLAST31
Repeati323 – 357WDPROSITE-ProRule annotationAdd BLAST35

Keywords - Domaini

WD repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0265 Eukaryota
ENOG410XSEW LUCA
HOVERGENiHBG105197
KOiK12857
OMAiGDCENYG
OrthoDBiEOG091G0DR4

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR020472 G-protein_beta_WD-40_rep
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PfamiView protein in Pfam
PF00400 WD40, 7 hits
PRINTSiPR00320 GPROTEINBRPT
SMARTiView protein in SMART
SM00320 WD40, 7 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 5 hits
PS50082 WD_REPEATS_2, 7 hits
PS50294 WD_REPEATS_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

A0MNP2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIEQQKRKGP ELPLVPVKRQ RHELLLGAGS GPGAGQQQAT PGALLQAGPP
60 70 80 90 100
RCSSLQAPIM LLSGHEGEVY CCKFHPNGST LASAGFDRLI LLWNVYGDCD
110 120 130 140 150
NYATLKGHSG AVMELHYNTD GSMLFSASTD KTVAVWDSET GERVKRLKGH
160 170 180 190 200
TSFVNSCYPA RRGPQLVCTG SDDGTVKLWD IRKKAAIQTF QNTYQVLAVT
210 220 230 240 250
FNDTSDQIIS GGIDNDIKVW DLRQNKLTYT MRGHADSVTG LSLSSEGSYL
260 270 280 290 300
LSNAMDNTVR VWDVRPFAPK ERCVKIFQGN VHNFEKNLLR CSWSPDGSKI
310 320 330 340 350
AAGSADRFVY VWDTTSRRIL YKLPGHAGSI NEVAFHPDEP IIISASSDKR

LYMGEIQ
Length:357
Mass (Da):39,311
Last modified:December 12, 2006 - v1
Checksum:iDE8CADEB098E560C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF011621 mRNA Translation: ABK41111.1
AK074516 mRNA Translation: BAG51963.1
CH471059 Genomic DNA Translation: EAX07626.1
RefSeqiNP_004805.2, NM_004814.2
UniGeneiHs.33962

Genome annotation databases

GeneIDi9410
KEGGihsa:9410

Similar proteinsi

Entry informationi

Entry nameiA0MNP2_HUMAN
AccessioniPrimary (citable) accession number: A0MNP2
Entry historyiIntegrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: May 23, 2018
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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