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Protein
Submitted name:

CDW11/WDR57

Gene

WDR57

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
CDW11/WDR57Imported
Submitted name:
WD repeat domain 57 (U5 snRNP specific), isoform CRA_aImported
Submitted name:
cDNA FLJ90035 fis, clone HEMBA1001878, highly similar to WD repeat protein 57Imported
Gene namesi
Name:WDR57Imported
ORF Names:hCG_20041Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA164726132.

Expressioni

Gene expression databases

BgeeiENSG00000060688.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000263694.

Structurei

3D structure databases

SMRiA0MNP2. Positions 9-356.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini62 – 357296WD_REPEATS_REGIONInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG0265. Eukaryota.
ENOG410XSEW. LUCA.
HOVERGENiHBG105197.
KOiK12857.
OMAiMSGHEGE.
OrthoDBiEOG091G0DR4.
PhylomeDBiA0MNP2.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 7 hits.
[Graphical view]
PRINTSiPR00320. GPROTEINBRPT.
SMARTiSM00320. WD40. 7 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS00678. WD_REPEATS_1. 5 hits.
PS50082. WD_REPEATS_2. 7 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0MNP2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIEQQKRKGP ELPLVPVKRQ RHELLLGAGS GPGAGQQQAT PGALLQAGPP
60 70 80 90 100
RCSSLQAPIM LLSGHEGEVY CCKFHPNGST LASAGFDRLI LLWNVYGDCD
110 120 130 140 150
NYATLKGHSG AVMELHYNTD GSMLFSASTD KTVAVWDSET GERVKRLKGH
160 170 180 190 200
TSFVNSCYPA RRGPQLVCTG SDDGTVKLWD IRKKAAIQTF QNTYQVLAVT
210 220 230 240 250
FNDTSDQIIS GGIDNDIKVW DLRQNKLTYT MRGHADSVTG LSLSSEGSYL
260 270 280 290 300
LSNAMDNTVR VWDVRPFAPK ERCVKIFQGN VHNFEKNLLR CSWSPDGSKI
310 320 330 340 350
AAGSADRFVY VWDTTSRRIL YKLPGHAGSI NEVAFHPDEP IIISASSDKR

LYMGEIQ
Length:357
Mass (Da):39,311
Last modified:December 12, 2006 - v1
Checksum:iDE8CADEB098E560C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF011621 mRNA. Translation: ABK41111.1.
AK074516 mRNA. Translation: BAG51963.1.
CH471059 Genomic DNA. Translation: EAX07626.1.
RefSeqiNP_004805.2. NM_004814.2.
UniGeneiHs.33962.

Genome annotation databases

GeneIDi9410.
KEGGihsa:9410.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF011621 mRNA. Translation: ABK41111.1.
AK074516 mRNA. Translation: BAG51963.1.
CH471059 Genomic DNA. Translation: EAX07626.1.
RefSeqiNP_004805.2. NM_004814.2.
UniGeneiHs.33962.

3D structure databases

SMRiA0MNP2. Positions 9-356.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000263694.

Protocols and materials databases

DNASUi9410.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi9410.
KEGGihsa:9410.

Organism-specific databases

CTDi9410.
PharmGKBiPA164726132.

Phylogenomic databases

eggNOGiKOG0265. Eukaryota.
ENOG410XSEW. LUCA.
HOVERGENiHBG105197.
KOiK12857.
OMAiMSGHEGE.
OrthoDBiEOG091G0DR4.
PhylomeDBiA0MNP2.

Miscellaneous databases

ChiTaRSiSNRNP40. human.
GenomeRNAii9410.

Gene expression databases

BgeeiENSG00000060688.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 7 hits.
[Graphical view]
PRINTSiPR00320. GPROTEINBRPT.
SMARTiSM00320. WD40. 7 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS00678. WD_REPEATS_1. 5 hits.
PS50082. WD_REPEATS_2. 7 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA0MNP2_HUMAN
AccessioniPrimary (citable) accession number: A0MNP2
Entry historyi
Integrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: September 7, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.