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Protein
Submitted name:

CDW11/WDR57

Gene

WDR57

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
CDW11/WDR57Imported
Submitted name:
WD repeat domain 57 (U5 snRNP specific), isoform CRA_aImported
Submitted name:
cDNA FLJ90035 fis, clone HEMBA1001878, highly similar to WD repeat protein 57Imported
Gene namesi
Name:WDR57Imported
ORF Names:hCG_20041Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000060688.12.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA164726132.

Expressioni

Gene expression databases

BgeeiENSG00000060688.
ExpressionAtlasiA0MNP2. baseline and differential.

Structurei

3D structure databases

SMRiA0MNP2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini62 – 357WD_REPEATS_REGIONInterPro annotationAdd BLAST296
Repeati62 – 95WDPROSITE-ProRule annotationAdd BLAST34
Repeati105 – 146WDPROSITE-ProRule annotationAdd BLAST42
Repeati147 – 189WDPROSITE-ProRule annotationAdd BLAST43
Repeati189 – 230WDPROSITE-ProRule annotationAdd BLAST42
Repeati231 – 265WDPROSITE-ProRule annotationAdd BLAST35
Repeati292 – 322WDPROSITE-ProRule annotationAdd BLAST31
Repeati323 – 357WDPROSITE-ProRule annotationAdd BLAST35

Keywords - Domaini

WD repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0265. Eukaryota.
ENOG410XSEW. LUCA.
HOVERGENiHBG105197.
KOiK12857.
OMAiGDCENYG.
OrthoDBiEOG091G0DR4.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiView protein in InterPro
IPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
PfamiView protein in Pfam
PF00400. WD40. 7 hits.
PRINTSiPR00320. GPROTEINBRPT.
SMARTiView protein in SMART
SM00320. WD40. 7 hits.
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiView protein in PROSITE
PS00678. WD_REPEATS_1. 5 hits.
PS50082. WD_REPEATS_2. 7 hits.
PS50294. WD_REPEATS_REGION. 1 hit.

Sequencei

Sequence statusi: Complete.

A0MNP2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIEQQKRKGP ELPLVPVKRQ RHELLLGAGS GPGAGQQQAT PGALLQAGPP
60 70 80 90 100
RCSSLQAPIM LLSGHEGEVY CCKFHPNGST LASAGFDRLI LLWNVYGDCD
110 120 130 140 150
NYATLKGHSG AVMELHYNTD GSMLFSASTD KTVAVWDSET GERVKRLKGH
160 170 180 190 200
TSFVNSCYPA RRGPQLVCTG SDDGTVKLWD IRKKAAIQTF QNTYQVLAVT
210 220 230 240 250
FNDTSDQIIS GGIDNDIKVW DLRQNKLTYT MRGHADSVTG LSLSSEGSYL
260 270 280 290 300
LSNAMDNTVR VWDVRPFAPK ERCVKIFQGN VHNFEKNLLR CSWSPDGSKI
310 320 330 340 350
AAGSADRFVY VWDTTSRRIL YKLPGHAGSI NEVAFHPDEP IIISASSDKR

LYMGEIQ
Length:357
Mass (Da):39,311
Last modified:December 12, 2006 - v1
Checksum:iDE8CADEB098E560C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF011621 mRNA. Translation: ABK41111.1.
AK074516 mRNA. Translation: BAG51963.1.
CH471059 Genomic DNA. Translation: EAX07626.1.
RefSeqiNP_004805.2. NM_004814.2.
UniGeneiHs.33962.

Genome annotation databases

GeneIDi9410.
KEGGihsa:9410.

Similar proteinsi

Entry informationi

Entry nameiA0MNP2_HUMAN
AccessioniPrimary (citable) accession number: A0MNP2
Entry historyiIntegrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: September 27, 2017
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.