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Protein
Submitted name:

Globin H

Gene

NGB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi64Iron (heme distal ligand)PROSITE-ProRule annotation1
Metal bindingi96Iron (heme proximal ligand)PROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Biological processOxygen transportPROSITE-ProRule annotation, Transport
LigandHemePROSITE-ProRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Globin HImported
Submitted name:
NeuroglobinImported
Submitted name:
Neuroglobin, isoform CRA_aImported
Submitted name:
cDNA, FLJ96443, Homo sapiens neuroglobin (NGB), mRNAImported
Gene namesi
Name:NGBImported
Synonyms:GLNHImported
ORF Names:hCG_22274Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000165553.4.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA31612.

Expressioni

Gene expression databases

BgeeiENSG00000165553.
ExpressionAtlasiA0M8W9. baseline and differential.

Structurei

3D structure databases

SMRiA0M8W9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 144GLOBINInterPro annotationAdd BLAST140

Sequence similaritiesi

Belongs to the globin family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3378. Eukaryota.
COG1018. LUCA.
HOVERGENiHBG039321.
OMAiDHVTKVM.
OrthoDBiEOG091G0R7W.

Family and domain databases

InterProiView protein in InterPro
IPR000971. Globin.
IPR009050. Globin-like.
PfamiView protein in Pfam
PF00042. Globin. 1 hit.
SUPFAMiSSF46458. SSF46458. 1 hit.
PROSITEiView protein in PROSITE
PS01033. GLOBIN. 1 hit.

Sequencei

Sequence statusi: Complete.

A0M8W9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERPEPELIR QSWRAVSRSP LEHGTVLFAR LFALEPDLLP LFQYNCRQFS
60 70 80 90 100
SPEDCLSSPE FLDHIRKVML VIDAAVTNVE DLSSLEEYLA SLGRKHRAVG
110 120 130 140 150
VKLSSFSTVG ESLLYMLEKC LGPAFTPATR AAWSQLYGAV VQAMSRGWDG

E
Length:151
Mass (Da):16,933
Last modified:December 12, 2006 - v1
Checksum:i45A292A7D77B9CE3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ008010 Genomic DNA. Translation: AAY16983.1.
AK315395 mRNA. Translation: BAG37788.1.
CH471061 Genomic DNA. Translation: EAW81274.1.
LT548107 Genomic DNA. Translation: SAI82145.1.
RefSeqiNP_067080.1. NM_021257.3.
UniGeneiHs.274363.

Genome annotation databases

GeneIDi58157.
KEGGihsa:58157.

Similar proteinsi

Entry informationi

Entry nameiA0M8W9_HUMAN
AccessioniPrimary (citable) accession number: A0M8W9
Entry historyiIntegrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: September 27, 2017
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.