A0M6Q0 (A0M6Q0_GRAFK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Thymidine kinase HAMAP MF_00124 RuleBase RU000544
EC=2.7.1.21 HAMAP MF_00124 RuleBase RU000544

Gene names

Name:	tdk HAMAP MF_00124 EMBL CAL68295.1
Ordered Locus Names:	GFO_3354

Organism

Gramella forsetii (strain KT0803) [Complete proteome] [HAMAP]

Taxonomic identifier

411154 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Flavobacteriia › Flavobacteriales › Flavobacteriaceae › Gramella

Protein attributes

Sequence length	215 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + thymidine = ADP + thymidine 5'-phosphate. HAMAP MF_00124 RuleBase RU000544 SAAS SAAS020634
Subunit structure	Homotetramer By similarity. HAMAP MF_00124
Subcellular location	Cytoplasm By similarity HAMAP MF_00124.
Sequence similarities	Belongs to the thymidine kinase family. HAMAP MF_00124 RuleBase RU004165

Ontologies

Keywords
Biological process	DNA synthesis HAMAP MF_00124 RuleBase RU000544 SAAS SAAS020634
Cellular component	Cytoplasm HAMAP MF_00124
Ligand	ATP-binding HAMAP MF_00124 RuleBase RU000544 SAAS SAAS020634 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00124 RuleBase RU000544 SAAS SAAS020634 EMBL CAL68295.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP thymidine kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	21 – 28	8	ATP By similarity HAMAP MF_00124
	Nucleotide binding	93 – 96	4	ATP By similarity HAMAP MF_00124
Sites
	Active site	94	1	Proton acceptor By similarity HAMAP MF_00124

Sequences

	Sequence		Length	Mass (Da)
	A0M6Q0 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: E21C285911132086	FASTA	215	24,366
	10 20 30 40 50 60 MFLENTVNHE EQFGWIEVIC GSMFSGKTEE LIRRLKRAKF AKQNVEIFKP AIDTRYDEEM 70 80 90 100 110 120 VVSHDSNEIR STPVPSASNI RLLADGCDVV GIDEAQFFDD EIVTVCNDLA NRGVRVIVAG 130 140 150 160 170 180 LDMDFKGNPF GPMPNLMATA EYVTKVHAVC TRTGNLAQFS YRKAINDDLV FLGENEEYEP 190 200 210 LSRAAYYKAM LRERVRKLDV NDAEELNQKA KEENA

References

[1]

"Whole genome analysis of the marine Bacteroidetes'Gramella forsetii' reveals adaptations to degradation of polymeric organic matter." Bauer M., Kube M., Teeling H., Richter M., Lombardot T., Allers E., Wuerdemann C.A., Quast C., Kuhl H., Knaust F., Woebken D., Bischof K., Mussmann M., Choudhuri J.V., Meyer F., Reinhardt R., Amann R.I., Gloeckner F.O. Environ. Microbiol. 8:2201-2213(2006) [PubMed: 17107561] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU207366 Genomic DNA. Translation: CAL68295.1.
RefSeq	YP_863362.1. NC_008571.1.
3D structure databases
ProteinModelPortal	A0M6Q0.
ModBase	Search...
Protein-protein interaction databases
STRING	A0M6Q0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4652263.
GenomeReviews	Gene locus GFO_3354 in contig CU207366_GR.
KEGG	gfo:GFO_3354.
NMPDR	fig|411154.5.peg.3165.
PATRIC	22075440. VBIGraFor5527_3233.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1435.
HOGENOM	HBG522108.
OMA	EPRCRHH.
ProtClustDB	PRK04296.
Family and domain databases
HAMAP	MF_00124. Thymidine_kinase. [Tree]
InterPro	IPR001267. Thymidine_kinase. IPR020634. Thymidine_kinase_subgr. [Graphical view]
KO	K00857.
PANTHER	PTHR11441. TK_cell. 1 hit.
Pfam	PF00265. TK. 1 hit. [Graphical view]
PIRSF	PIRSF035805. TK_cell. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A0M6Q0_GRAFK

Accession

Primary (citable) accession number: A0M6Q0

Entry history

Integrated into UniProtKB/TrEMBL:	December 12, 2006
Last sequence update:	December 12, 2006
Last modified:	December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)