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A0M6P9 (A0M6P9_GRAFK) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Alanine racemase HAMAP-Rule MF_01201

EC=5.1.1.1 HAMAP-Rule MF_01201
Gene names
Name:alr EMBL CAL68294.1
Ordered Locus Names:GFO_3353 EMBL CAL68294.1
OrganismGramella forsetii (strain KT0803) [Complete proteome] [HAMAP]
Taxonomic identifier411154 [NCBI]
Taxonomic lineageBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeGramella

Protein attributes

Sequence length369 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site381Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2641Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1361Substrate By similarity HAMAP-Rule MF_01201
Binding site3131Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue381N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
A0M6P9 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: 487B9400E2E95535

FASTA36941,435
        10         20         30         40         50         60 
MPEAKETVLE INLGNLAHNY RFLRSKTDKE AKFLSVVKAH AYGSDSVEIA KKLEELGTDY 

        70         80         90        100        110        120 
FAVAYVEEGI RLRENGISKP ILVLHPQPSH FEEIIEHCLE PNLYSQKTLE SFVSLAERLN 

       130        140        150        160        170        180 
QKNYPVHIKL NTGLNRLGFD QSEIPRVFET IKNTNSIKIA SVFSHLAASE DWQEREFTLS 

       190        200        210        220        230        240 
QIDLFRKMTW QLIENLDYEP LLHICNTSGV INYPKAAFSM VRTGIGLYGY SNDKTIDPHL 

       250        260        270        280        290        300 
KPVGKLKTII SQIRKLDPGA SVGYNRAFKT EKESKIATLP IGHADGINRI YGKQKAGVFV 

       310        320        330        340        350        360 
NGKYAPIVGN VCMDIIMIDV TGIDCEEGDE VIIFGGPQHP VDFARAGGTI SYELITGIQR 


RVTRKIIPE 

« Hide

References

[1]"Whole genome analysis of the marine Bacteroidetes'Gramella forsetii' reveals adaptations to degradation of polymeric organic matter."
Bauer M., Kube M., Teeling H., Richter M., Lombardot T., Allers E., Wuerdemann C.A., Quast C., Kuhl H., Knaust F., Woebken D., Bischof K., Mussmann M., Choudhuri J.V., Meyer F., Reinhardt R., Amann R.I., Gloeckner F.O.
Environ. Microbiol. 8:2201-2213(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: KT0803.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU207366 Genomic DNA. Translation: CAL68294.1.
RefSeqYP_863361.1. NC_008571.1.

3D structure databases

ProteinModelPortalA0M6P9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING411154.GFO_3353.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAL68294; CAL68294; GFO_3353.
GeneID4652677.
KEGGgfo:GFO_3353.
PATRIC22075438. VBIGraFor5527_3232.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHOG000031444.
KOK01775.
OMAFLGEDYH.
OrthoDBEOG6PP9NJ.
ProtClustDBCLSK2399160.

Enzyme and pathway databases

BioCycGFOR411154:GI79-3353-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA0M6P9_GRAFK
AccessionPrimary (citable) accession number: A0M6P9
Entry history
Integrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: February 19, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)