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A0M6B8 (A0M6B8_GRAFK) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323
EC=4.99.1.1 HAMAP MF_00323
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323 EMBL CAL68163.1
Ordered Locus Names:GFO_3220
OrganismGramella forsetii (strain KT0803) [Complete proteome] [HAMAP]
Taxonomic identifier411154 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Flavobacteriia › Flavobacteriales › Flavobacteriaceae › Gramella

Protein attributes

Sequence length344 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding1891Iron By similarity HAMAP MF_00323
Metal binding2921Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
A0M6B8 [UniParc].

Last modified December 12, 2006. Version 1.
Checksum: D073133B75D62CA3

FASTA34439,599
        10         20         30         40         50         60 
MSKGVLLVNL GSPDSTDPKD VKKYLGEFLM DERVIDVPYW ARTLLVKGIV LNTRPKKSAE 

        70         80         90        100        110        120 
AYQKIWWEEG SPLIVLSERL QAKIDDHTSV PISLAMRYGT PNIKQGMQEL HDQGVDEVLL 

       130        140        150        160        170        180 
FPLYPQFAMA TTETILVLAE ELRKEHFPDM SFTTVPSFYN HPDYIRTLAN SISESLQDKE 

       190        200        210        220        230        240 
YEHLLFSYHG VPERHIRKSD ITNSHCKIDG SCCQSPSTAH QFCYRHQCFE TTRLVAEYLG 

       250        260        270        280        290        300 
LKENTYSVSF QSRLGFDPWL KPYTDRTIER FGKQGMKKLA IVTPAFVSDC LETLEEIAME 

       310        320        330        340 
GEEIFHEVGG EKFTVVPCLN DREEWVKVLS RWIDEWAHQK PVEA

« Hide

References

[1]"Whole genome analysis of the marine Bacteroidetes'Gramella forsetii' reveals adaptations to degradation of polymeric organic matter."
Bauer M., Kube M., Teeling H., Richter M., Lombardot T., Allers E., Wuerdemann C.A., Quast C., Kuhl H., Knaust F., Woebken D., Bischof K., Mussmann M., Choudhuri J.V., Meyer F., Reinhardt R., Amann R.I., Gloeckner F.O.
Environ. Microbiol. 8:2201-2213(2006) [PubMed: 17107561] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CU207366 Genomic DNA. Translation: CAL68163.1.
RefSeqYP_863230.1. NC_008571.1.

3D structure databases

ProteinModelPortalA0M6B8.
ModBaseSearch...

Protein-protein interaction databases

STRINGA0M6B8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4651309.
GenomeReviewsGene locus GFO_3220 in contig CU207366_GR.
KEGGgfo:GFO_3220.
NMPDRfig|411154.5.peg.3034.
PATRIC22075176. VBIGraFor5527_3103.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0276.
HOGENOMHBG697135.
OMAIRPAKSA.
PhylomeDBA0M6B8.
ProtClustDBCLSK851820.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA0M6B8_GRAFK
AccessionPrimary (citable) accession number: A0M6B8
Entry history
Integrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: December 14, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info