SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A0M5T1

- SYL_GRAFK

UniProt

A0M5T1 - SYL_GRAFK

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Leucine--tRNA ligase

Gene
leuS, GFO_3032
Organism
Gramella forsetii (strain KT0803)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei740 – 7401ATP By similarity

GO - Molecular functioni

  1. aminoacyl-tRNA editing activity Source: InterPro
  2. ATP binding Source: UniProtKB-HAMAP
  3. leucine-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. leucyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciGFOR411154:GI79-3032-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucine--tRNA ligase (EC:6.1.1.4)
Alternative name(s):
Leucyl-tRNA synthetase
Short name:
LeuRS
Gene namesi
Name:leuS
Ordered Locus Names:GFO_3032
OrganismiGramella forsetii (strain KT0803)
Taxonomic identifieri411154 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeGramella
ProteomesiUP000000755: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 962962Leucine--tRNA ligaseUniRule annotationPRO_1000009347Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi411154.GFO_3032.

Structurei

3D structure databases

ProteinModelPortaliA0M5T1.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi40 – 5112"HIGH" regionUniRule annotationAdd
BLAST
Motifi737 – 7415"KMSKS" regionUniRule annotation

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0495.
HOGENOMiHOG000200748.
KOiK01869.
OMAiDKPKYYA.
OrthoDBiEOG63Z74X.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.40.50.620. 5 hits.
3.90.740.10. 1 hit.
HAMAPiMF_00049_B. Leu_tRNA_synth_B.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view]
PANTHERiPTHR11946:SF7. PTHR11946:SF7. 1 hit.
PfamiPF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 2 hits.
PF13603. tRNA-synt_1_2. 1 hit.
[Graphical view]
PRINTSiPR00985. TRNASYNTHLEU.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0M5T1-1 [UniParc]FASTAAdd to Basket

« Hide

MSYHFNKIEE KWQKYWADNQ TFKASNDSEK PKYYVLDMFP YPSGAGLHVG    50
HPLGYIASDI YARFKRHKGF NVLHPQGYDS FGLPAEQYAI QTGQHPAVTT 100
ENNIARYREQ LDKIGFSFDW SREVRTSEPD YYKWTQWIFI QLFESWYDQE 150
AEKSRAITEL EEIFTSEGNS RINAASDDDV EKFSADDWNA CSEDEKEQIL 200
LKYRLTYLAE AEVNWCPQLG TVLANDEIVN GVSERGGYPV VRKKMTQWSM 250
RISAFSERLL QDLNKIDWTE SLKESQRNWI GKSVGAHVDF KIENSKFKIG 300
VFTTRPDTIF GVSFMTLAPE HELVEKITTE DRKEEVQAYI EASAKRSERE 350
RMADVKTISG AFTGAYAEHP FTKKPVPIWI GDYVLAGYGT GAVMAVPCGD 400
QRDHDFARHF DLLIPNIFEN VDVSQEAYAG KEGTVIANSD FLSGLEYKEA 450
LNKVILELEK TGQGYGKTNY RLRDAVFSRQ RYWGEPFPVY YVNGLPKMID 500
EKYLPLKLPE VEKYLPTETG EPPLGNATDW AWDSKNNKVV SNKVLKQSRK 550
LSGQHDEPNS NVTPSAVEGS DDNGIYPLEL NTMPGWAGSS WYLFRYMGAG 600
NPDRFVSEEA QKYWENVDLY IGGSEHATGH LLYSRFWTKF LYDRGWLTVE 650
EPFKKLINQG MILGTSAFVY RLEGENVFVS KNQINGNNVQ PIHADVSLVN 700
SSDELDIEGF KKWRPEFADA KFLTEDGKYI VGREVEKMSK SKYNVVNPDE 750
ICQDYGADTL RMYEMFLGPL EQAKPWNTAG ITGVHNFLKK LWKLYYDGEE 800
FFVSDEKASA DSLKTFHKTI KKVTEDIEEF SFNTSVSTFM ICVNELTAQK 850
CNSREILEPL AVLIAPYAPH IAEELWEKLG NSESVTTAKY PEFEEKYLVE 900
SMKNYPVSFN GKMRFTMELS LDMSKEEIEK TVMADERTQK QLDGRTPKKV 950
IVVPGKIVNI VG 962
Length:962
Mass (Da):110,237
Last modified:December 12, 2006 - v1
Checksum:iF535EE086A219AC2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU207366 Genomic DNA. Translation: CAL67976.1.
RefSeqiWP_011710877.1. NC_008571.1.
YP_863043.1. NC_008571.1.

Genome annotation databases

EnsemblBacteriaiCAL67976; CAL67976; GFO_3032.
GeneIDi4652867.
KEGGigfo:GFO_3032.
PATRICi22074808. VBIGraFor5527_2920.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU207366 Genomic DNA. Translation: CAL67976.1 .
RefSeqi WP_011710877.1. NC_008571.1.
YP_863043.1. NC_008571.1.

3D structure databases

ProteinModelPortali A0M5T1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 411154.GFO_3032.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAL67976 ; CAL67976 ; GFO_3032 .
GeneIDi 4652867.
KEGGi gfo:GFO_3032.
PATRICi 22074808. VBIGraFor5527_2920.

Phylogenomic databases

eggNOGi COG0495.
HOGENOMi HOG000200748.
KOi K01869.
OMAi DKPKYYA.
OrthoDBi EOG63Z74X.

Enzyme and pathway databases

BioCyci GFOR411154:GI79-3032-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.40.50.620. 5 hits.
3.90.740.10. 1 hit.
HAMAPi MF_00049_B. Leu_tRNA_synth_B.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view ]
PANTHERi PTHR11946:SF7. PTHR11946:SF7. 1 hit.
Pfami PF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 2 hits.
PF13603. tRNA-synt_1_2. 1 hit.
[Graphical view ]
PRINTSi PR00985. TRNASYNTHLEU.
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Whole genome analysis of the marine Bacteroidetes'Gramella forsetii' reveals adaptations to degradation of polymeric organic matter."
    Bauer M., Kube M., Teeling H., Richter M., Lombardot T., Allers E., Wuerdemann C.A., Quast C., Kuhl H., Knaust F., Woebken D., Bischof K., Mussmann M., Choudhuri J.V., Meyer F., Reinhardt R., Amann R.I., Gloeckner F.O.
    Environ. Microbiol. 8:2201-2213(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KT0803.

Entry informationi

Entry nameiSYL_GRAFK
AccessioniPrimary (citable) accession number: A0M5T1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 12, 2006
Last modified: September 3, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi