A0M5Q1 (A0M5Q1_GRAFK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Deoxyribose-phosphate aldolase 2 HAMAP MF_00114
Short name=DERA 2 HAMAP MF_00114
EC=4.1.2.4 HAMAP MF_00114

Alternative name(s):
2-deoxy-D-ribose 5-phosphate aldolase 2 HAMAP MF_00114
Phosphodeoxyriboaldolase 2 HAMAP MF_00114

Gene names

Name:	deoC EMBL CAL67946.1
Synonyms:	deoC2 HAMAP MF_00114
Ordered Locus Names:	GFO_3000

Organism

Gramella forsetii (strain KT0803) [Complete proteome] [HAMAP]

Taxonomic identifier

411154 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Flavobacteriia › Flavobacteriales › Flavobacteriaceae › Gramella

Protein attributes

Sequence length	212 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate By similarity. HAMAP MF_00114 SAAS SAAS022979
Catalytic activity	2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00114 SAAS SAAS022979
Pathway	Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP MF_00114 SAAS SAAS022979
Subcellular location	Cytoplasm By similarity HAMAP MF_00114 SAAS SAAS022979.
Sequence similarities	Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. HAMAP MF_00114

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00114 SAAS SAAS022979
Ligand	Schiff base HAMAP MF_00114 SAAS SAAS022979
Molecular function	Lyase SAAS SAAS022979 HAMAP MF_00114 EMBL CAL67946.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate catabolic process Inferred from electronic annotation. Source: HAMAP deoxyribonucleotide catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	deoxyribose-phosphate aldolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	151	1	Schiff-base intermediate with acetaldehyde By similarity HAMAP MF_00114
	Active site	180	1	By similarity HAMAP MF_00114

Sequences

	Sequence		Length	Mass (Da)
	A0M5Q1 [UniParc]. Last modified December 12, 2006. Version 1. Checksum: 9077495B1F5A6458	FASTA	212	23,060
	10 20 30 40 50 60 MNINKYIDHT LLAATAQSEE IQKLCFEAKK FGFYAVCVNS SRVKVAKNEL VETDVKIAAT 70 80 90 100 110 120 IGFPLGACFT EAKIAEAVKS VQDGADEIDM VINIGFLKDG KSAEVQREIL YIKKAIENCV 130 140 150 160 170 180 LKVIIETCYL SEKEIMKACE LAMQAGADFI KTSTGFGSRG ASYDDIKIMK KVVGEEIKIK 190 200 210 ASGGIKDAET AMKYINLGVH RIGTSSGIKI IS

References

[1]

"Whole genome analysis of the marine Bacteroidetes'Gramella forsetii' reveals adaptations to degradation of polymeric organic matter." Bauer M., Kube M., Teeling H., Richter M., Lombardot T., Allers E., Wuerdemann C.A., Quast C., Kuhl H., Knaust F., Woebken D., Bischof K., Mussmann M., Choudhuri J.V., Meyer F., Reinhardt R., Amann R.I., Gloeckner F.O. Environ. Microbiol. 8:2201-2213(2006) [PubMed: 17107561] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU207366 Genomic DNA. Translation: CAL67946.1.
RefSeq	YP_863013.1. NC_008571.1.
3D structure databases
ProteinModelPortal	A0M5Q1.
ModBase	Search...
Protein-protein interaction databases
STRING	A0M5Q1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4651116.
GenomeReviews	Gene locus GFO_3000 in contig CU207366_GR.
KEGG	gfo:GFO_3000.
NMPDR	fig|411154.5.peg.2828.
PATRIC	22074742. VBIGraFor5527_2889.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0274.
HOGENOM	HBG636421.
OMA	IDHTNLK.
PhylomeDB	A0M5Q1.
ProtClustDB	CLSK781935.
Family and domain databases
HAMAP	MF_00114. DeoC_type1. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/AroFGH_arch. IPR022979. Deoxyribose_phosphate_aldo_1. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01619.
PANTHER	PTHR10889. DeoC. 1 hit.
Pfam	PF01791. DeoC. 1 hit. [Graphical view]
PIRSF	PIRSF001357. DeoC. 1 hit.
TIGRFAMs	TIGR00126. DeoC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A0M5Q1_GRAFK

Accession

Primary (citable) accession number: A0M5Q1

Entry history

Integrated into UniProtKB/TrEMBL:	December 12, 2006
Last sequence update:	December 12, 2006
Last modified:	December 14, 2011
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)